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The map label for this gene is yycG [H]

Identifier: 78221237

GI number: 78221237

Start: 13386

End: 15677

Strand: Direct

Name: yycG [H]

Synonym: Gmet_0009

Alternate gene names: 78221237

Gene position: 13386-15677 (Clockwise)

Preceding gene: 78221236

Following gene: 78221238

Centisome position: 0.33

GC content: 62.52

Gene sequence:

>2292_bases
ATGAACCTGCGCCTCACGATCAGGAACAAGCTTTTTCTGGCTACCCTCCTCATTCTCTTCATCTCCTACGCCATCCTTAT
CCAGACAACCGTCACCAGCATCAACACCTCCCTTGAAGACAACCTGGCCAAGGAACTTGCCGAGAACCTCCGCTACGCCA
AAGACCAGTACTTCTCCCGGGCAGAGCACCTGAAGTACGCCCTCCTCCTCCCCGCCTCCGCGCAGACGGTGCAGGAGCGG
GTCGAGAGGAGGGACAGGGTCTGGCTCCAGGAGACGGCGCGGCGCTGGAAGACCAGCCTCCCCTTCGCTGAGCCGTTCCT
CTTTGTGGACCCGCAGCTGAAGGTCATCGCCGGCGATGGCGAGTCGGTGCCGGAGAATGTCCGCGAACTGGCTCCCATCG
TGGAACGGGCGCTGCGGGAAAAACGGCCCGTTTCCGCAACCGAGCTGGTGAGCGACCGTTTCCTCTGCAGCGCCGGGGTC
CGCGACTTCTGCTCCCGTCCTCCCTACGGAGACGGGAGCGTCATGATGATAACCGTCGTCGTCCCGGTACTGGCCGAGGG
GGGGGAGGCCCTGGGCGCCATCGTGGCCGGGGAAGTCATCGACCGGGACGTGAAGCAGGCGGCCGGGACTCAGGAGATTT
TCGGCAAGCAGGTGGTTGTGGCCGTCATCCGTGGCAATAGGCTTGCCCCGGCCGGCGTCAATCCTGCCTTCCCCTACCCT
GCAGCCATCGCTCCCGATATCCTCGACAAGCTGGAGCGGGGGCAGTCGTTCGGAGGCGACGTCACCATCGGGGGAAAGGC
CTACAAGACCGCTATCTCACCCCTCACCAACAGCCGCGGAGACTACGTGGGTTCCCTCTACGTGGCCCTCTCCCGGGACG
ATTTAAAGGGGATCCTCGGCGACAGCCTCAAGAATATCCTCGTATCCGCCGCCATCGGCATCGTCCTCACGTTTCTGACG
GCCTTCCACGTGGCCCGCAGGTTGACCATGCCCCTGAACGCCCTTGCCGGCGGGGTGCGAAAGATCGAGAGCGGGGACTT
GCGGCAACGGGTGGAGGTAACCACCGCCGACGAAGTGGGAGAGTTGGGAGAAGCCTTCAACCGCATGGCCCGAAGCCTGG
AGGAGCGGGACCGGACCATCCGGGCCACGGCCCACGAACAGGCGGAGCTGAACCGCAAGCTCCAGGAGATGAATGAACAC
CTCGAAGAGAACGTGAGCGAACGGACAACAGCCCTGCAGATGGAGATGGGGCGTCTTGAGGCGATTCTCACCGGCATGGC
TGAAGGAATTGCCGTCACCGACCGGGAGGGGAAAGTCATCCTCTTTAACCCCGCGGCCCAGCGGATCTTCGAGATGGTTC
CCCCCCGGGTAATGGGGCATACCCTGGAGGAACTCTGTGCCGGCGGAGAGTTCTGTGCCCTCGCCGATTACGTCCGCACC
ATGAAAGAAACCGATGACTTGACCCCCCGCCGGGACGTGGAGATGTCCATGAAGGGGAAGAAACTCACGATCAGCCTTTC
ACCTTTCTGCGACCAGGGGGGAGCCTTGGCCGGCGTCGTCATGTCGGTGCGCGATGTGACCGGGGAAGAGGATGTGGATC
GGGTGAAGACCGAGTTCATCTCCACGGTGTCCCATGAGCTCAAGACCCCCCTCACCTCCATCAAGGGTTCGCTCCAGTTC
ATCCACGACCGGGGGGAAGGGTTCGGCGGGATGGAGGGGGAGCTTCTCTCCGTCTGTCTCCGTAACACCGACCGGCTGAT
CCGGCTCGTGAACGATATCCTCGACATTGCCCGGATCGAATCGGGGCGGCTGGAGTTCGTGCCGGAGCCCCAGGATGTGC
GGACCCTGGTCACCCACTCCATCGAGGAGCTGGCAGGGTACGCTCTGGAGCATGACGTCAGCGTCGAGAACCGCTGTGGC
CAGGACCTCCCCCCCATCTATGGGGACCGGGACCGTCTCGTGCAGGTTCTCACCAACCTCCTCTCCAACGCGATCAAGTT
TTCACCCCGGGGGGAACGGGTGGTGGTGACGGCGGAGCGGACTTCAAACTACGTGGCCATATCCGTGGGTGACCGGGGAC
GGGAGATCCTGTGGTCGGATCGGGGGAAACTCTTCAAGAAATTTCAGCTGCTCGACAATTCGGACCGCCGTCAGCACGGC
GGGACGGGCCTTGGGCTTGCCATTTGCAAGGAAATCGTCGAACATCACCACGGCAGGATCTTCTACAACGAAGGGACCGG
GGGGGGGAACGTTTTCACCTTCACGGTTCCCGTCTATGAGGAACAATCATGA

Upstream 100 bases:

>100_bases
ACAAGCCGGCACGGCAGGCGGTCCTTGAACTCATGACCCGCGACCCGAAGGCCGAGCGGGGGTAGGAACCCGAGTCCCCA
CACCCGTCGGAGGGTATGCC

Downstream 100 bases:

>100_bases
ATAACCTCAAAATCCTCATCGTCGATGACGAAGCGGACATCGCCCTCATTCTCAAGCTGCAACTGGAGGACGCCGGCTAC
CGCACCACCCGGGCCCGGGA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MNLRLTIRNKLFLATLLILFISYAILIQTTVTSINTSLEDNLAKELAENLRYAKDQYFSRAEHLKYALLLPASAQTVQER
VERRDRVWLQETARRWKTSLPFAEPFLFVDPQLKVIAGDGESVPENVRELAPIVERALREKRPVSATELVSDRFLCSAGV
RDFCSRPPYGDGSVMMITVVVPVLAEGGEALGAIVAGEVIDRDVKQAAGTQEIFGKQVVVAVIRGNRLAPAGVNPAFPYP
AAIAPDILDKLERGQSFGGDVTIGGKAYKTAISPLTNSRGDYVGSLYVALSRDDLKGILGDSLKNILVSAAIGIVLTFLT
AFHVARRLTMPLNALAGGVRKIESGDLRQRVEVTTADEVGELGEAFNRMARSLEERDRTIRATAHEQAELNRKLQEMNEH
LEENVSERTTALQMEMGRLEAILTGMAEGIAVTDREGKVILFNPAAQRIFEMVPPRVMGHTLEELCAGGEFCALADYVRT
MKETDDLTPRRDVEMSMKGKKLTISLSPFCDQGGALAGVVMSVRDVTGEEDVDRVKTEFISTVSHELKTPLTSIKGSLQF
IHDRGEGFGGMEGELLSVCLRNTDRLIRLVNDILDIARIESGRLEFVPEPQDVRTLVTHSIEELAGYALEHDVSVENRCG
QDLPPIYGDRDRLVQVLTNLLSNAIKFSPRGERVVVTAERTSNYVAISVGDRGREILWSDRGKLFKKFQLLDNSDRRQHG
GTGLGLAICKEIVEHHHGRIFYNEGTGGGNVFTFTVPVYEEQS

Sequences:

>Translated_763_residues
MNLRLTIRNKLFLATLLILFISYAILIQTTVTSINTSLEDNLAKELAENLRYAKDQYFSRAEHLKYALLLPASAQTVQER
VERRDRVWLQETARRWKTSLPFAEPFLFVDPQLKVIAGDGESVPENVRELAPIVERALREKRPVSATELVSDRFLCSAGV
RDFCSRPPYGDGSVMMITVVVPVLAEGGEALGAIVAGEVIDRDVKQAAGTQEIFGKQVVVAVIRGNRLAPAGVNPAFPYP
AAIAPDILDKLERGQSFGGDVTIGGKAYKTAISPLTNSRGDYVGSLYVALSRDDLKGILGDSLKNILVSAAIGIVLTFLT
AFHVARRLTMPLNALAGGVRKIESGDLRQRVEVTTADEVGELGEAFNRMARSLEERDRTIRATAHEQAELNRKLQEMNEH
LEENVSERTTALQMEMGRLEAILTGMAEGIAVTDREGKVILFNPAAQRIFEMVPPRVMGHTLEELCAGGEFCALADYVRT
MKETDDLTPRRDVEMSMKGKKLTISLSPFCDQGGALAGVVMSVRDVTGEEDVDRVKTEFISTVSHELKTPLTSIKGSLQF
IHDRGEGFGGMEGELLSVCLRNTDRLIRLVNDILDIARIESGRLEFVPEPQDVRTLVTHSIEELAGYALEHDVSVENRCG
QDLPPIYGDRDRLVQVLTNLLSNAIKFSPRGERVVVTAERTSNYVAISVGDRGREILWSDRGKLFKKFQLLDNSDRRQHG
GTGLGLAICKEIVEHHHGRIFYNEGTGGGNVFTFTVPVYEEQS
>Mature_763_residues
MNLRLTIRNKLFLATLLILFISYAILIQTTVTSINTSLEDNLAKELAENLRYAKDQYFSRAEHLKYALLLPASAQTVQER
VERRDRVWLQETARRWKTSLPFAEPFLFVDPQLKVIAGDGESVPENVRELAPIVERALREKRPVSATELVSDRFLCSAGV
RDFCSRPPYGDGSVMMITVVVPVLAEGGEALGAIVAGEVIDRDVKQAAGTQEIFGKQVVVAVIRGNRLAPAGVNPAFPYP
AAIAPDILDKLERGQSFGGDVTIGGKAYKTAISPLTNSRGDYVGSLYVALSRDDLKGILGDSLKNILVSAAIGIVLTFLT
AFHVARRLTMPLNALAGGVRKIESGDLRQRVEVTTADEVGELGEAFNRMARSLEERDRTIRATAHEQAELNRKLQEMNEH
LEENVSERTTALQMEMGRLEAILTGMAEGIAVTDREGKVILFNPAAQRIFEMVPPRVMGHTLEELCAGGEFCALADYVRT
MKETDDLTPRRDVEMSMKGKKLTISLSPFCDQGGALAGVVMSVRDVTGEEDVDRVKTEFISTVSHELKTPLTSIKGSLQF
IHDRGEGFGGMEGELLSVCLRNTDRLIRLVNDILDIARIESGRLEFVPEPQDVRTLVTHSIEELAGYALEHDVSVENRCG
QDLPPIYGDRDRLVQVLTNLLSNAIKFSPRGERVVVTAERTSNYVAISVGDRGREILWSDRGKLFKKFQLLDNSDRRQHG
GTGLGLAICKEIVEHHHGRIFYNEGTGGGNVFTFTVPVYEEQS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=336, Percent_Identity=27.0833333333333, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=29.368029739777, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788549, Length=390, Percent_Identity=26.6666666666667, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=32.9059829059829, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=31.3807531380753, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=33.7962962962963, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=31.3304721030043, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI48994928, Length=293, Percent_Identity=28.6689419795222, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=28.6290322580645, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=29.5652173913043, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=27.5109170305677, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=26.3829787234043, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=26.5486725663717, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790551, Length=254, Percent_Identity=26.7716535433071, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=25.764192139738, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790300, Length=361, Percent_Identity=22.7146814404432, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84262; Mature: 84262

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRLTIRNKLFLATLLILFISYAILIQTTVTSINTSLEDNLAKELAENLRYAKDQYFSR
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AEHLKYALLLPASAQTVQERVERRDRVWLQETARRWKTSLPFAEPFLFVDPQLKVIAGDG
HHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCC
ESVPENVRELAPIVERALREKRPVSATELVSDRFLCSAGVRDFCSRPPYGDGSVMMITVV
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHH
VPVLAEGGEALGAIVAGEVIDRDVKQAAGTQEIFGKQVVVAVIRGNRLAPAGVNPAFPYP
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHEEEEEECCEECCCCCCCCCCCC
AAIAPDILDKLERGQSFGGDVTIGGKAYKTAISPLTNSRGDYVGSLYVALSRDDLKGILG
CCCCHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHH
DSLKNILVSAAIGIVLTFLTAFHVARRLTMPLNALAGGVRKIESGDLRQRVEVTTADEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEEECCHHHHH
ELGEAFNRMARSLEERDRTIRATAHEQAELNRKLQEMNEHLEENVSERTTALQMEMGRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILTGMAEGIAVTDREGKVILFNPAAQRIFEMVPPRVMGHTLEELCAGGEFCALADYVRT
HHHHHHHCCCEEECCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MKETDDLTPRRDVEMSMKGKKLTISLSPFCDQGGALAGVVMSVRDVTGEEDVDRVKTEFI
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
STVSHELKTPLTSIKGSLQFIHDRGEGFGGMEGELLSVCLRNTDRLIRLVNDILDIARIE
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGRLEFVPEPQDVRTLVTHSIEELAGYALEHDVSVENRCGQDLPPIYGDRDRLVQVLTNL
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHH
LSNAIKFSPRGERVVVTAERTSNYVAISVGDRGREILWSDRGKLFKKFQLLDNSDRRQHG
HHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCEEHHCHHHHHHHHHHHHCCCCCHHCC
GTGLGLAICKEIVEHHHGRIFYNEGTGGGNVFTFTVPVYEEQS
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MNLRLTIRNKLFLATLLILFISYAILIQTTVTSINTSLEDNLAKELAENLRYAKDQYFSR
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AEHLKYALLLPASAQTVQERVERRDRVWLQETARRWKTSLPFAEPFLFVDPQLKVIAGDG
HHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCC
ESVPENVRELAPIVERALREKRPVSATELVSDRFLCSAGVRDFCSRPPYGDGSVMMITVV
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCHHHHH
VPVLAEGGEALGAIVAGEVIDRDVKQAAGTQEIFGKQVVVAVIRGNRLAPAGVNPAFPYP
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHEEEEEECCEECCCCCCCCCCCC
AAIAPDILDKLERGQSFGGDVTIGGKAYKTAISPLTNSRGDYVGSLYVALSRDDLKGILG
CCCCHHHHHHHHCCCCCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHH
DSLKNILVSAAIGIVLTFLTAFHVARRLTMPLNALAGGVRKIESGDLRQRVEVTTADEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHEEECCHHHHH
ELGEAFNRMARSLEERDRTIRATAHEQAELNRKLQEMNEHLEENVSERTTALQMEMGRLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILTGMAEGIAVTDREGKVILFNPAAQRIFEMVPPRVMGHTLEELCAGGEFCALADYVRT
HHHHHHHCCCEEECCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
MKETDDLTPRRDVEMSMKGKKLTISLSPFCDQGGALAGVVMSVRDVTGEEDVDRVKTEFI
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
STVSHELKTPLTSIKGSLQFIHDRGEGFGGMEGELLSVCLRNTDRLIRLVNDILDIARIE
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGRLEFVPEPQDVRTLVTHSIEELAGYALEHDVSVENRCGQDLPPIYGDRDRLVQVLTNL
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHH
LSNAIKFSPRGERVVVTAERTSNYVAISVGDRGREILWSDRGKLFKKFQLLDNSDRRQHG
HHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCEEHHCHHHHHHHHHHHHCCCCCHHCC
GTGLGLAICKEIVEHHHGRIFYNEGTGGGNVFTFTVPVYEEQS
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]