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The map label for this gene is cobB [H]

Identifier: 78189911

GI number: 78189911

Start: 2487099

End: 2488517

Strand: Reverse

Name: cobB [H]

Synonym: Cag_1958

Alternate gene names: 78189911

Gene position: 2488517-2487099 (Counterclockwise)

Preceding gene: 78189912

Following gene: 78189910

Centisome position: 96.75

GC content: 48.06

Gene sequence:

>1419_bases
ATGGAGATGGTGCAATTGCCTCGCTTAGTGGTGTCGGCTGCGCAAAAAAGCGCAGGTAAAACAACACTAACGCTTGGCTT
GCTTGCTTATTTTGCGGCGAAGGGTATTGCTATTCGGAGCTTTAAAAAAGGTCCCGATTACATTGACCCTGCATGGCATT
CGCTTGCAACGGGGCATCCTTGTTATAACCTTGACCCATGGCTTATGGGAAGTGAGGGATGCCTTGCGGCATTACTTCAG
CGTGGTTATTGCGAGGCTGCACGAGGCTCATTAGTACTGATTGAAGGCAATCATGGTTTGCACGATGGGCTTTCGTTGGA
TGGAAGCGATAGTACGGCTGGGCTTGCGGCGTTAACCAACTCCCCTGTTTTGCTTGTTGTTGATAGCCGTCATGTAAGTC
GAGGGATTGCTGCTACCGTGTTGGGTTTGCAACAAATGGCACCGCACGCTACGATTCGTGGTGTGGTTTTAAATCGGGTG
CGCACGGCTCGGCAGGCAGCAAAGCAGCGTGCGGCTATTGAGCATTATTGCGGCATTCCCGTGCTTGGTGAACTTCCTGC
TGACAGTCGCATGATTATTGCGGAGCGTCATCTTGGGTTAACCACGGTAGCCGAAACAACGGGTGCGCGTGCATTCATTG
ATACGGTCGCTGATATTGTTGGGCAATCGTGCAATATGGAGGCAATTCATGCTCTTTTTTTAGAAGCGCCACCGTTACTC
GTTGATAACGTTGTGTCGTTACCTGAAGGTTGTACAACATTATCGAAACCACGCATTGTACGTATTGGGGTATTTCGTGA
TGCTGCATTTTGTTTTTACTACCCCGATAATTTGGAAGCTTTGGAGCGAGCTGGTGGTGAATTGGTGTTCATCAATTCAC
TTGAAGCAACCTCTCTTCCTGAGATTGATGGCTTATATCTTGGTGGTGGTTTTCCAGAATCCTTTTTTGAGCAACTTAGT
AGTAACAACCAATTACTTGCTGAGGTGCGTCAAGCAATTGATGGTGGGTTGCCCACCTATGCGGAGTGTGGAGGACTTAT
TTACCTCTGCCAAGCTGCAATATATCAGGGCAAAAAGTACCAGCTTGCAGGCGTTCTACCAGTAACTATTGGCTTTAATA
AAAAACCTGCTGGACATGGCTATGTAGAGTTGGAAAGCAAGGTTGATAGCGCGTGGTATTGCAAAGGTGAACGGCTTAAA
GCGCATGAATTTCATTACGGTTATCCGCTTGAGCAAGATGGTGGTTCACTCTTTCAGTTCCATGTGCTTCGCGGGCATGG
TGTAACGGGCAACAGCGATGGATTTTTGTATAAAAATCTCTTTGCATCGTTTGCTCATCTTCATGCAAGCGCAACAACGG
AGTGGGCACCGCGTTTTGTGGCGTTAGCAAGGGCGAATCAGCAGCCTCAACGATGTTGA

Upstream 100 bases:

>100_bases
GCAAACAGTAATGGTTGTTGGTGTCGGAGAGTTATCCGTGGTGATTGCTCTCCGACTTTTGTTTTTTGCTCAATTGGGAA
TAACCGTGATCGGCTAAAGA

Downstream 100 bases:

>100_bases
AATGACCCCCAAAAAAAGCAAACATATTTGTTGTTTACCATTTGCAATAGTGCCTCACAAATTGTTAATTATATAACTGT
ATAATTGTTAATATTTCGCT

Product: cobyrinic acid a,c-diamide synthase CbiA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEMVQLPRLVVSAAQKSAGKTTLTLGLLAYFAAKGIAIRSFKKGPDYIDPAWHSLATGHPCYNLDPWLMGSEGCLAALLQ
RGYCEAARGSLVLIEGNHGLHDGLSLDGSDSTAGLAALTNSPVLLVVDSRHVSRGIAATVLGLQQMAPHATIRGVVLNRV
RTARQAAKQRAAIEHYCGIPVLGELPADSRMIIAERHLGLTTVAETTGARAFIDTVADIVGQSCNMEAIHALFLEAPPLL
VDNVVSLPEGCTTLSKPRIVRIGVFRDAAFCFYYPDNLEALERAGGELVFINSLEATSLPEIDGLYLGGGFPESFFEQLS
SNNQLLAEVRQAIDGGLPTYAECGGLIYLCQAAIYQGKKYQLAGVLPVTIGFNKKPAGHGYVELESKVDSAWYCKGERLK
AHEFHYGYPLEQDGGSLFQFHVLRGHGVTGNSDGFLYKNLFASFAHLHASATTEWAPRFVALARANQQPQRC

Sequences:

>Translated_472_residues
MEMVQLPRLVVSAAQKSAGKTTLTLGLLAYFAAKGIAIRSFKKGPDYIDPAWHSLATGHPCYNLDPWLMGSEGCLAALLQ
RGYCEAARGSLVLIEGNHGLHDGLSLDGSDSTAGLAALTNSPVLLVVDSRHVSRGIAATVLGLQQMAPHATIRGVVLNRV
RTARQAAKQRAAIEHYCGIPVLGELPADSRMIIAERHLGLTTVAETTGARAFIDTVADIVGQSCNMEAIHALFLEAPPLL
VDNVVSLPEGCTTLSKPRIVRIGVFRDAAFCFYYPDNLEALERAGGELVFINSLEATSLPEIDGLYLGGGFPESFFEQLS
SNNQLLAEVRQAIDGGLPTYAECGGLIYLCQAAIYQGKKYQLAGVLPVTIGFNKKPAGHGYVELESKVDSAWYCKGERLK
AHEFHYGYPLEQDGGSLFQFHVLRGHGVTGNSDGFLYKNLFASFAHLHASATTEWAPRFVALARANQQPQRC
>Mature_472_residues
MEMVQLPRLVVSAAQKSAGKTTLTLGLLAYFAAKGIAIRSFKKGPDYIDPAWHSLATGHPCYNLDPWLMGSEGCLAALLQ
RGYCEAARGSLVLIEGNHGLHDGLSLDGSDSTAGLAALTNSPVLLVVDSRHVSRGIAATVLGLQQMAPHATIRGVVLNRV
RTARQAAKQRAAIEHYCGIPVLGELPADSRMIIAERHLGLTTVAETTGARAFIDTVADIVGQSCNMEAIHALFLEAPPLL
VDNVVSLPEGCTTLSKPRIVRIGVFRDAAFCFYYPDNLEALERAGGELVFINSLEATSLPEIDGLYLGGGFPESFFEQLS
SNNQLLAEVRQAIDGGLPTYAECGGLIYLCQAAIYQGKKYQLAGVLPVTIGFNKKPAGHGYVELESKVDSAWYCKGERLK
AHEFHYGYPLEQDGGSLFQFHVLRGHGVTGNSDGFLYKNLFASFAHLHASATTEWAPRFVALARANQQPQRC

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 50869; Mature: 50869

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMVQLPRLVVSAAQKSAGKTTLTLGLLAYFAAKGIAIRSFKKGPDYIDPAWHSLATGHP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHCCCCC
CYNLDPWLMGSEGCLAALLQRGYCEAARGSLVLIEGNHGLHDGLSLDGSDSTAGLAALTN
CCCCCCCEECCHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECC
SPVLLVVDSRHVSRGIAATVLGLQQMAPHATIRGVVLNRVRTARQAAKQRAAIEHYCGIP
CCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLGELPADSRMIIAERHLGLTTVAETTGARAFIDTVADIVGQSCNMEAIHALFLEAPPLL
EECCCCCCCEEEEEECCCCEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
VDNVVSLPEGCTTLSKPRIVRIGVFRDAAFCFYYPDNLEALERAGGELVFINSLEATSLP
HHHHHHCCCCCCCCCCCCEEEEEEEECCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCC
EIDGLYLGGGFPESFFEQLSSNNQLLAEVRQAIDGGLPTYAECGGLIYLCQAAIYQGKKY
CCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCEE
QLAGVLPVTIGFNKKPAGHGYVELESKVDSAWYCKGERLKAHEFHYGYPLEQDGGSLFQF
EEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
HVLRGHGVTGNSDGFLYKNLFASFAHLHASATTEWAPRFVALARANQQPQRC
EEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEMVQLPRLVVSAAQKSAGKTTLTLGLLAYFAAKGIAIRSFKKGPDYIDPAWHSLATGHP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHCCCCC
CYNLDPWLMGSEGCLAALLQRGYCEAARGSLVLIEGNHGLHDGLSLDGSDSTAGLAALTN
CCCCCCCEECCHHHHHHHHHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECC
SPVLLVVDSRHVSRGIAATVLGLQQMAPHATIRGVVLNRVRTARQAAKQRAAIEHYCGIP
CCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLGELPADSRMIIAERHLGLTTVAETTGARAFIDTVADIVGQSCNMEAIHALFLEAPPLL
EECCCCCCCEEEEEECCCCEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHH
VDNVVSLPEGCTTLSKPRIVRIGVFRDAAFCFYYPDNLEALERAGGELVFINSLEATSLP
HHHHHHCCCCCCCCCCCCEEEEEEEECCEEEEECCCCHHHHHHCCCCEEEEECCCCCCCC
EIDGLYLGGGFPESFFEQLSSNNQLLAEVRQAIDGGLPTYAECGGLIYLCQAAIYQGKKY
CCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCEE
QLAGVLPVTIGFNKKPAGHGYVELESKVDSAWYCKGERLKAHEFHYGYPLEQDGGSLFQF
EEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCEEEE
HVLRGHGVTGNSDGFLYKNLFASFAHLHASATTEWAPRFVALARANQQPQRC
EEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA