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The map label for this gene is ytfL [C]

Identifier: 78189885

GI number: 78189885

Start: 2463544

End: 2464914

Strand: Reverse

Name: ytfL [C]

Synonym: Cag_1932

Alternate gene names: 78189885

Gene position: 2464914-2463544 (Counterclockwise)

Preceding gene: 78189886

Following gene: 78189884

Centisome position: 95.83

GC content: 47.05

Gene sequence:

>1371_bases
ATGGAAATATTTCTACTTTTTGTTCTCATACTTGTCAATGGCGCGTTTGCCATGTCGGAAATTGCGTTAGTAACAGCTAA
ACGTTCTCGACTTTCGCGCCTTGCGGACGATGGGGATAAATCTGCCACTACGGCAATGAAGTTGGGGGAAGATTCCACCA
GCTTTCTTTCCACCATTCAAATTGGCATCACCTCCATTGGTATTCTCAACGGTATTGTTGGAGAAGGGGCGTTAGCCGTT
CCCTTTTCACTATTCATTCATTCGGCAACAGGCATTGAGTTAGAAACCGCTCAGCTTATTGCTACCGTTGTTGTGGTGCT
TGGCATTACCTACGTTACCATTGTGGTGGGTGAATTGGTACCAAAACGGCTTGGGCAGCTTAATCCCGAACAAATTGCCT
GTTTGGTTGCTCGCCCCATGCAAATACTTGCCACAATTACTCGTCCTTTTGGGCGCTTGCTCTCCTTTTCAACCAACACG
TTGCTTCGTTTAATGGGGGTTAAACCGCAAATTACCCCAAGCGTTACTGAAGAGGAAATTCATGCTATGCTTGAAGAGGG
TTCCGAAGCAGGGGTGATTGAACAGCAAGAGCGCGATATGGTGCGCAATGTGTTTCGCCTTGACGACCGCCAGCTTGGTT
CGCTCATGGTACCTCGTGCCGATATTGTTTTTCTTGATGTAACTCAACCGCTTGAGGAGAATATTTGCCGTGTAACGGAG
TCGGAGCATTCGCGTTTTCCTGTATGCAACGGTAATCTTCAATCGCTACTTGGCGTGGTGAATGCAAAGCAGTTGTTGCT
TAAAACCTTGCGCGGCGGTTTAACCGAATTTGCAACACTCTTGCAGCCATGTGTGTATGTGCCCGAAACGCTTACGGGCA
TGGAATTGCTTGACCACTTTAGAACTTCTGGTACGCAAATGGTTTTTGTGGTTGATGAGTATGGTGAAATTCAAGGCTTA
GTTACCTTACAAGATTTGCTTGAAGCTGTAACGGGTGAATTTGTGCCGCGCAACCTTGAAGATTCATGGGCAGTTGAGCG
TGCCGATGGTTCGTGGTTGCTTGATGGCTTAATTCCCGTGCCTGAATTAAAAGATACGCTCAAGCTTAAAGAGGTGCCCG
ATGAGGATAAGGGGCTTTACCACACCTTAAGTGGAATGATTATGTGGTTGCTTGGTAGAATGCCGCATACGGGCGATGTG
CTTGTTTGGGAAGAGTGGAATTTGGAAATTGTTGACCTTGACGGGCAGCGCATTGATAAAGTGCTTGCTTCACCACTCAA
CAATGCACCAAAAGCATCTCAAAAAGAGGAAAAGCCGCCCGTCAAATCAGACGATAATGCGGCTTTGTGTTCCATACGCC
CAACGCCGTAA

Upstream 100 bases:

>100_bases
GCGAAGCCGAATGCCCAAAAGAGATTAAAGTTGTTCATATTGCCCGAATGAATCGTGAATTTCTTGTAGCCTCTCTTTTT
GGGGATTAAGAACTTTTTCA

Downstream 100 bases:

>100_bases
AGAGATGATACCTTAACATATCCACCAAAACTATGAGCCACAATCAAGAACAAGATTGCCTTTTCTGCCGCATTGTGCGG
GGTGAAATTCCTGCAACCAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MEIFLLFVLILVNGAFAMSEIALVTAKRSRLSRLADDGDKSATTAMKLGEDSTSFLSTIQIGITSIGILNGIVGEGALAV
PFSLFIHSATGIELETAQLIATVVVVLGITYVTIVVGELVPKRLGQLNPEQIACLVARPMQILATITRPFGRLLSFSTNT
LLRLMGVKPQITPSVTEEEIHAMLEEGSEAGVIEQQERDMVRNVFRLDDRQLGSLMVPRADIVFLDVTQPLEENICRVTE
SEHSRFPVCNGNLQSLLGVVNAKQLLLKTLRGGLTEFATLLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQGL
VTLQDLLEAVTGEFVPRNLEDSWAVERADGSWLLDGLIPVPELKDTLKLKEVPDEDKGLYHTLSGMIMWLLGRMPHTGDV
LVWEEWNLEIVDLDGQRIDKVLASPLNNAPKASQKEEKPPVKSDDNAALCSIRPTP

Sequences:

>Translated_456_residues
MEIFLLFVLILVNGAFAMSEIALVTAKRSRLSRLADDGDKSATTAMKLGEDSTSFLSTIQIGITSIGILNGIVGEGALAV
PFSLFIHSATGIELETAQLIATVVVVLGITYVTIVVGELVPKRLGQLNPEQIACLVARPMQILATITRPFGRLLSFSTNT
LLRLMGVKPQITPSVTEEEIHAMLEEGSEAGVIEQQERDMVRNVFRLDDRQLGSLMVPRADIVFLDVTQPLEENICRVTE
SEHSRFPVCNGNLQSLLGVVNAKQLLLKTLRGGLTEFATLLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQGL
VTLQDLLEAVTGEFVPRNLEDSWAVERADGSWLLDGLIPVPELKDTLKLKEVPDEDKGLYHTLSGMIMWLLGRMPHTGDV
LVWEEWNLEIVDLDGQRIDKVLASPLNNAPKASQKEEKPPVKSDDNAALCSIRPTP
>Mature_456_residues
MEIFLLFVLILVNGAFAMSEIALVTAKRSRLSRLADDGDKSATTAMKLGEDSTSFLSTIQIGITSIGILNGIVGEGALAV
PFSLFIHSATGIELETAQLIATVVVVLGITYVTIVVGELVPKRLGQLNPEQIACLVARPMQILATITRPFGRLLSFSTNT
LLRLMGVKPQITPSVTEEEIHAMLEEGSEAGVIEQQERDMVRNVFRLDDRQLGSLMVPRADIVFLDVTQPLEENICRVTE
SEHSRFPVCNGNLQSLLGVVNAKQLLLKTLRGGLTEFATLLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQGL
VTLQDLLEAVTGEFVPRNLEDSWAVERADGSWLLDGLIPVPELKDTLKLKEVPDEDKGLYHTLSGMIMWLLGRMPHTGDV
LVWEEWNLEIVDLDGQRIDKVLASPLNNAPKASQKEEKPPVKSDDNAALCSIRPTP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=368, Percent_Identity=26.3586956521739, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1790664, Length=446, Percent_Identity=30.7174887892377, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI145693175, Length=428, Percent_Identity=27.803738317757, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87082033, Length=359, Percent_Identity=30.3621169916435, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788119, Length=266, Percent_Identity=32.7067669172932, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786879, Length=260, Percent_Identity=26.5384615384615, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50078; Mature: 50078

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFLLFVLILVNGAFAMSEIALVTAKRSRLSRLADDGDKSATTAMKLGEDSTSFLSTIQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHH
IGITSIGILNGIVGEGALAVPFSLFIHSATGIELETAQLIATVVVVLGITYVTIVVGELV
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRLGQLNPEQIACLVARPMQILATITRPFGRLLSFSTNTLLRLMGVKPQITPSVTEEEI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHH
HAMLEEGSEAGVIEQQERDMVRNVFRLDDRQLGSLMVPRADIVFLDVTQPLEENICRVTE
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCCCHHHHHHHHCC
SEHSRFPVCNGNLQSLLGVVNAKQLLLKTLRGGLTEFATLLQPCVYVPETLTGMELLDHF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
RTSGTQMVFVVDEYGEIQGLVTLQDLLEAVTGEFVPRNLEDSWAVERADGSWLLDGLIPV
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEECCCCCC
PELKDTLKLKEVPDEDKGLYHTLSGMIMWLLGRMPHTGDVLVWEEWNLEIVDLDGQRIDK
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCHHHHHH
VLASPLNNAPKASQKEEKPPVKSDDNAALCSIRPTP
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MEIFLLFVLILVNGAFAMSEIALVTAKRSRLSRLADDGDKSATTAMKLGEDSTSFLSTIQ
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHH
IGITSIGILNGIVGEGALAVPFSLFIHSATGIELETAQLIATVVVVLGITYVTIVVGELV
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PKRLGQLNPEQIACLVARPMQILATITRPFGRLLSFSTNTLLRLMGVKPQITPSVTEEEI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHH
HAMLEEGSEAGVIEQQERDMVRNVFRLDDRQLGSLMVPRADIVFLDVTQPLEENICRVTE
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCCCHHHHHHHHCC
SEHSRFPVCNGNLQSLLGVVNAKQLLLKTLRGGLTEFATLLQPCVYVPETLTGMELLDHF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
RTSGTQMVFVVDEYGEIQGLVTLQDLLEAVTGEFVPRNLEDSWAVERADGSWLLDGLIPV
HCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCEEECCCCCC
PELKDTLKLKEVPDEDKGLYHTLSGMIMWLLGRMPHTGDVLVWEEWNLEIVDLDGQRIDK
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCHHHHHH
VLASPLNNAPKASQKEEKPPVKSDDNAALCSIRPTP
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]