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The map label for this gene is gmhB [H]

Identifier: 78189763

GI number: 78189763

Start: 2328750

End: 2329352

Strand: Reverse

Name: gmhB [H]

Synonym: Cag_1807

Alternate gene names: 78189763

Gene position: 2329352-2328750 (Counterclockwise)

Preceding gene: 78189764

Following gene: 78189762

Centisome position: 90.56

GC content: 45.44

Gene sequence:

>603_bases
ATGAGCGAACAACAGCGCATTAAGGTGCTTTTTTTAGATCGTGATGGCACTATTAATCACGATACGGGTTCCTACATTAA
TTCTATTGAGCAATTTAAGCTGATTGAGCGTGCTGATGAGGCTATTGCACTTGCCAAGCAAGCGGGCTTTCGCATTGTGA
TTGTAAGCAATCAAGCTGGTATTGCGCGTGGCATTGCTACGTTTGAGCAAGTTGATACTGTTAACAGCCATTTGCAATCG
TTACTTGCACGTAAAAACGCCACCTACGACCGTTGCTATTACTGCCCTTACCATCCCAACTATCCTCATCCAGAGTATGA
CCTTTTAGCTGGTTTCCGTAAACCTGAAACAGGCATGGTTGAGCAGGCTGTTGCTGAATTTGCGGCTGAAGGGTTACAGG
TTGATCGCTCTGCCTCTTTTTTTGTTGGTGATAAGGTACTTGATGTTGAGTGTGGAGAACGTGCTGGACTTACCTCTGTG
TTAGTGCGCACGGGGCACAACGAAGAGGCACTCTGCTACGAGCGCAATATTCATCCTGCTTTTGTTGCTGACGATCTTTA
TCAAGCCATTACGGAATTTATTTTGCCCCATTCGCAAGAATAG

Upstream 100 bases:

>100_bases
GGTTGAGCGTGCCATGAGTAGTGATTTTAGTTGGCACAACACGGCAGAGGCGTATGGGCAGTTGTACCGCAATCTTCTTG
GCAAATAGGGGGGAAATGGT

Downstream 100 bases:

>100_bases
GGGGCATTGTAATAACTTTCTTCTCCGCATGTGAGCCTCTCTCTTTACCTGCACATTCCTTTCTGCCGAGAGCGCTGCCC
TTACTGCGATTTTTATTTAA

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSEQQRIKVLFLDRDGTINHDTGSYINSIEQFKLIERADEAIALAKQAGFRIVIVSNQAGIARGIATFEQVDTVNSHLQS
LLARKNATYDRCYYCPYHPNYPHPEYDLLAGFRKPETGMVEQAVAEFAAEGLQVDRSASFFVGDKVLDVECGERAGLTSV
LVRTGHNEEALCYERNIHPAFVADDLYQAITEFILPHSQE

Sequences:

>Translated_200_residues
MSEQQRIKVLFLDRDGTINHDTGSYINSIEQFKLIERADEAIALAKQAGFRIVIVSNQAGIARGIATFEQVDTVNSHLQS
LLARKNATYDRCYYCPYHPNYPHPEYDLLAGFRKPETGMVEQAVAEFAAEGLQVDRSASFFVGDKVLDVECGERAGLTSV
LVRTGHNEEALCYERNIHPAFVADDLYQAITEFILPHSQE
>Mature_199_residues
SEQQRIKVLFLDRDGTINHDTGSYINSIEQFKLIERADEAIALAKQAGFRIVIVSNQAGIARGIATFEQVDTVNSHLQSL
LARKNATYDRCYYCPYHPNYPHPEYDLLAGFRKPETGMVEQAVAEFAAEGLQVDRSASFFVGDKVLDVECGERAGLTSVL
VRTGHNEEALCYERNIHPAFVADDLYQAITEFILPHSQE

Specific function: Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=162, Percent_Identity=39.5061728395062, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082027, Length=157, Percent_Identity=27.3885350318471, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 22442; Mature: 22311

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQQRIKVLFLDRDGTINHDTGSYINSIEQFKLIERADEAIALAKQAGFRIVIVSNQAG
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
IARGIATFEQVDTVNSHLQSLLARKNATYDRCYYCPYHPNYPHPEYDLLAGFRKPETGMV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCHH
EQAVAEFAAEGLQVDRSASFFVGDKVLDVECGERAGLTSVLVRTGHNEEALCYERNIHPA
HHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCHH
FVADDLYQAITEFILPHSQE
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEQQRIKVLFLDRDGTINHDTGSYINSIEQFKLIERADEAIALAKQAGFRIVIVSNQAG
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
IARGIATFEQVDTVNSHLQSLLARKNATYDRCYYCPYHPNYPHPEYDLLAGFRKPETGMV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCHH
EQAVAEFAAEGLQVDRSASFFVGDKVLDVECGERAGLTSVLVRTGHNEEALCYERNIHPA
HHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCHH
FVADDLYQAITEFILPHSQE
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]