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The map label for this gene is tsf

Identifier: 78189604

GI number: 78189604

Start: 2144916

End: 2145782

Strand: Reverse

Name: tsf

Synonym: Cag_1647

Alternate gene names: 78189604

Gene position: 2145782-2144916 (Counterclockwise)

Preceding gene: 162319770

Following gene: 78189603

Centisome position: 83.43

GC content: 45.1

Gene sequence:

>867_bases
ATGAGTCAGATTTCAGCCGCAGATGTAAAAAATCTTCGTGATATAACGGGTGCAGGAATGATGGACTGCAAAAAAGCGCT
TGATGAAACAGGCGGCGATATGCAGCAAGCCATTGACTTTTTACGCAAAAAAGGTGCCGCACTTGCCGCTAAGCGTGCAG
ACCGTGAGGCACATGAAGGTATGATTCAGGTAAAGCTTGCTAATGATTGCAAGCGTGGTGTGTTGCTTGAACTCAATTGC
GAAACCGACTTTGTGGCGCGTGGTAACGACTTTACTTCGTTTACCGCAGCGCTTAGTGAGTTGGCACTTTCGCAATGTGT
AGCTTCAGCCGAGGCTATGTTGCCACTTGCACTTGGTGCCGCTTATGATGGCGAAACGGTTGATAGCGCTATGAAAACCA
TGACGGGTAAGCTTGGCGAAAAAATCAACCTCAAGCGCCTTGCATTTTTTGATATGCCTGATGGTGTGGTTGAAGGCTAC
ATTCACCCAGGTGCAAAGCTTGGAGCAATTGTTTCTCTTAAAACCGACAAGCCTGAACTTGTTGGTGAGCTTGCAAAAGA
CCTCGCAATGCAAATTGCTGCTGCTGCTCCAATTGTGGTTGATCGCTCAGGCGTTCCAGCCGATTATATTGCTAAAGAGG
CAGAAATTTATCGCCAGCAAGCCCTTGAGCAGGGTAAGAAAGAGGAGTTTGTTGATAAAATTGTTACGGGCAGACTTGAA
AAGTATTATCAAGATGTTGTGCTGACCGAGCAAGTTTTTATTAAAGATGACAAGCTTAAAGTTTCTGCAATGCTTGATCA
ATTCCGTAAAAAGAATCAAGCAACGCTTGATGTTGTAGGATTTGTTCGCTATCAGTTAGGCGAATAG

Upstream 100 bases:

>100_bases
GGTTTTGCACCTCTTGAATATTGTTAAGGCTTGTTGGCAAGTGTAGCAGTGTTCAGAGGTGCTTTGTTTTTAATTCCTTT
TAAATGAAGAGACGTTCATT

Downstream 100 bases:

>100_bases
TTTTTTTTAAAGCCTCGATTATTCGGGGCTTTTTTTTTTGCTCTTGAGATGGGTTGGCAAGAGAGCCGTTGTAAGCGGAA
ATATGTTACTAACGGAACCA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQISAADVKNLRDITGAGMMDCKKALDETGGDMQQAIDFLRKKGAALAAKRADREAHEGMIQVKLANDCKRGVLLELNC
ETDFVARGNDFTSFTAALSELALSQCVASAEAMLPLALGAAYDGETVDSAMKTMTGKLGEKINLKRLAFFDMPDGVVEGY
IHPGAKLGAIVSLKTDKPELVGELAKDLAMQIAAAAPIVVDRSGVPADYIAKEAEIYRQQALEQGKKEEFVDKIVTGRLE
KYYQDVVLTEQVFIKDDKLKVSAMLDQFRKKNQATLDVVGFVRYQLGE

Sequences:

>Translated_288_residues
MSQISAADVKNLRDITGAGMMDCKKALDETGGDMQQAIDFLRKKGAALAAKRADREAHEGMIQVKLANDCKRGVLLELNC
ETDFVARGNDFTSFTAALSELALSQCVASAEAMLPLALGAAYDGETVDSAMKTMTGKLGEKINLKRLAFFDMPDGVVEGY
IHPGAKLGAIVSLKTDKPELVGELAKDLAMQIAAAAPIVVDRSGVPADYIAKEAEIYRQQALEQGKKEEFVDKIVTGRLE
KYYQDVVLTEQVFIKDDKLKVSAMLDQFRKKNQATLDVVGFVRYQLGE
>Mature_287_residues
SQISAADVKNLRDITGAGMMDCKKALDETGGDMQQAIDFLRKKGAALAAKRADREAHEGMIQVKLANDCKRGVLLELNCE
TDFVARGNDFTSFTAALSELALSQCVASAEAMLPLALGAAYDGETVDSAMKTMTGKLGEKINLKRLAFFDMPDGVVEGYI
HPGAKLGAIVSLKTDKPELVGELAKDLAMQIAAAAPIVVDRSGVPADYIAKEAEIYRQQALEQGKKEEFVDKIVTGRLEK
YYQDVVLTEQVFIKDDKLKVSAMLDQFRKKNQATLDVVGFVRYQLGE

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=219, Percent_Identity=31.5068493150685, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786366, Length=288, Percent_Identity=37.1527777777778, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17561440, Length=304, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19921466, Length=219, Percent_Identity=29.6803652968037, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_CHLCH (Q3AQ26)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379942.1
- STRING:   Q3AQ26
- GeneID:   3747665
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1647
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   CCHL340177:CAG_1647-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31348; Mature: 31217

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISAADVKNLRDITGAGMMDCKKALDETGGDMQQAIDFLRKKGAALAAKRADREAHEG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
MIQVKLANDCKRGVLLELNCETDFVARGNDFTSFTAALSELALSQCVASAEAMLPLALGA
EEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYDGETVDSAMKTMTGKLGEKINLKRLAFFDMPDGVVEGYIHPGAKLGAIVSLKTDKPEL
CCCCHHHHHHHHHHHHHHCCCCCHHEEEEECCCCHHHHCCCCCCCHHCEEEEECCCCHHH
VGELAKDLAMQIAAAAPIVVDRSGVPADYIAKEAEIYRQQALEQGKKEEFVDKIVTGRLE
HHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYQDVVLTEQVFIKDDKLKVSAMLDQFRKKNQATLDVVGFVRYQLGE
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQISAADVKNLRDITGAGMMDCKKALDETGGDMQQAIDFLRKKGAALAAKRADREAHEG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
MIQVKLANDCKRGVLLELNCETDFVARGNDFTSFTAALSELALSQCVASAEAMLPLALGA
EEEEEECCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AYDGETVDSAMKTMTGKLGEKINLKRLAFFDMPDGVVEGYIHPGAKLGAIVSLKTDKPEL
CCCCHHHHHHHHHHHHHHCCCCCHHEEEEECCCCHHHHCCCCCCCHHCEEEEECCCCHHH
VGELAKDLAMQIAAAAPIVVDRSGVPADYIAKEAEIYRQQALEQGKKEEFVDKIVTGRLE
HHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYQDVVLTEQVFIKDDKLKVSAMLDQFRKKNQATLDVVGFVRYQLGE
HHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA