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The map label for this gene is dnaC [H]

Identifier: 78189568

GI number: 78189568

Start: 2100167

End: 2101702

Strand: Reverse

Name: dnaC [H]

Synonym: Cag_1608

Alternate gene names: 78189568

Gene position: 2101702-2100167 (Counterclockwise)

Preceding gene: 78189569

Following gene: 78189567

Centisome position: 81.71

GC content: 47.59

Gene sequence:

>1536_bases
ATGATATCGAAAAAAGCCGCACCCATTATAGATTTTAGTAAGGATATTGACTTTAGCCAAGAGAGTCGCATTCCCCCTTA
CTCCACCGAAGTGGAGCAAGAGGTGCTTGCATGTGTGTTGCTTGAAGATGAGCCTATTGAGCAGGTGATTCAAATTTTTG
GTGAAAGTAGCGAAGAGGTTTTTTACGAGCGTCGCCACCAAACCATTTTTCGCGCCATGATGCAGCTTTACCACAAGCGG
CAGGCAATTGATATTATTACCGTTAGTGAAGAGCTGCTCCGCATGGGCGAATTAGAGGTAGTTGGTGGACGCCACTACCT
TGCGGAGCTTTCAGGCAAAGTAATTAGTGCGGCAAACATTGAGTATTACGCCCGACTTGCTAAAGAGAAGTTTCTTTACC
GCCGTCTTATTTCCATTGCTACAAAAATTTCGGGTGTAGCTTACAACTCCTCAATGGATATTTTTGATTTGGTGGAACAT
GCCTCGCAGCAGTTTTTTACCATTTCACAAGCGGGCGTTAAAAAGAAGGCATCGCCCATTAAAGAGTTGGTGAAAACGGG
TATTCGTATGTTGGAGAATTTGCGTGCCTCGCAATCCTCCGTAACGGGCGTAGCTTCGGGCTTTTCGGAGCTTGACCAAT
TTACGGCAGGCTTTCAACCATCGGATATGATTATTATTGCCGCCCGTCCATCGGCTGGTAAAACCGCTTTTTCCTTAGCG
TTAGCTCGCAATGCAGCCGTTGATTTTAATACGCCCGTACTCTTCTTTAGCCTTGAAATGGCGGAAGTGCAGCTTGCTAT
TCGTTTAATGTGCGCCGAAGCCTATGTAGAGTCGCAGCTTGTGCGTACCGGACGCATTACGCCCGAAATGATGGGGCGCA
TTATTAATAGCATGGATAAGCTAAACGAGGCAAAGCTCTTTATTGACGACACGCCCGGCATCTCCATTATGGAGCTTGCC
GCTAAAACGCGCCGCATGAAGCAAGAGCAAAATATTGGCATGGTGGTAGTGGATTACTTGCAGCTTGTAACCCCCGTGCG
CGATGGTCGCACCAATCGTGAGCAAGAGATTGCGCAAATTTCCCGATCGCTTAAAGCCTTAGCCAAAGAGCTGAATATTC
CCATTATTGCCCTTGCACAGCTTAACCGCTCGGTTGAACAGCGTTCGGGCGATCGCCGTCCGCAACTGAGCGATTTGCGC
GAATCTGGCTCTATTGAGCAAGATGCCGACGTGGTAATGTTCCTTTCGCGCCCCGAAATGTATGGCAAAAACACCTTTGA
GGATGGCACCTCAACCAAGGATATTGTTGAAATTGTGATTGGTAAGCAGCGTAACGGACCTATTGGCGACATTCGTTTGC
TCTTTTTAAAAAATTACGGTCGTTTTCAGTCCACGGCAAATGTCTATATTACCGCAAATGCCGAAGCTGAAAGCGCACCT
CAAGCAGAGCCTGAACGCTATTTGCAACCATCGCAAGAGTTCCCACCACCAGCAAGTGGCGGCGCTTTTATTGCGCAAGA
TGATGCACCGTTTTAA

Upstream 100 bases:

>100_bases
TCTTCGCTTCGCTCCGCAATGACAATAAAATGACTTTTGCAGAGTTTCCTTAACAAAAGCCTCATTAACACTCCCTTATT
CGTAAAGAGTACCCAAACGC

Downstream 100 bases:

>100_bases
GGTGATTGAGCTTGTATTCTCTGATTGAAGGAGAGAGAGTTGGAGAGAGCCTTGCACAGCTTTCGTGATAAACAATAGTA
TTTGAAAATTTAGTACCGCA

Product: DnaB helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MISKKAAPIIDFSKDIDFSQESRIPPYSTEVEQEVLACVLLEDEPIEQVIQIFGESSEEVFYERRHQTIFRAMMQLYHKR
QAIDIITVSEELLRMGELEVVGGRHYLAELSGKVISAANIEYYARLAKEKFLYRRLISIATKISGVAYNSSMDIFDLVEH
ASQQFFTISQAGVKKKASPIKELVKTGIRMLENLRASQSSVTGVASGFSELDQFTAGFQPSDMIIIAARPSAGKTAFSLA
LARNAAVDFNTPVLFFSLEMAEVQLAIRLMCAEAYVESQLVRTGRITPEMMGRIINSMDKLNEAKLFIDDTPGISIMELA
AKTRRMKQEQNIGMVVVDYLQLVTPVRDGRTNREQEIAQISRSLKALAKELNIPIIALAQLNRSVEQRSGDRRPQLSDLR
ESGSIEQDADVVMFLSRPEMYGKNTFEDGTSTKDIVEIVIGKQRNGPIGDIRLLFLKNYGRFQSTANVYITANAEAESAP
QAEPERYLQPSQEFPPPASGGAFIAQDDAPF

Sequences:

>Translated_511_residues
MISKKAAPIIDFSKDIDFSQESRIPPYSTEVEQEVLACVLLEDEPIEQVIQIFGESSEEVFYERRHQTIFRAMMQLYHKR
QAIDIITVSEELLRMGELEVVGGRHYLAELSGKVISAANIEYYARLAKEKFLYRRLISIATKISGVAYNSSMDIFDLVEH
ASQQFFTISQAGVKKKASPIKELVKTGIRMLENLRASQSSVTGVASGFSELDQFTAGFQPSDMIIIAARPSAGKTAFSLA
LARNAAVDFNTPVLFFSLEMAEVQLAIRLMCAEAYVESQLVRTGRITPEMMGRIINSMDKLNEAKLFIDDTPGISIMELA
AKTRRMKQEQNIGMVVVDYLQLVTPVRDGRTNREQEIAQISRSLKALAKELNIPIIALAQLNRSVEQRSGDRRPQLSDLR
ESGSIEQDADVVMFLSRPEMYGKNTFEDGTSTKDIVEIVIGKQRNGPIGDIRLLFLKNYGRFQSTANVYITANAEAESAP
QAEPERYLQPSQEFPPPASGGAFIAQDDAPF
>Mature_511_residues
MISKKAAPIIDFSKDIDFSQESRIPPYSTEVEQEVLACVLLEDEPIEQVIQIFGESSEEVFYERRHQTIFRAMMQLYHKR
QAIDIITVSEELLRMGELEVVGGRHYLAELSGKVISAANIEYYARLAKEKFLYRRLISIATKISGVAYNSSMDIFDLVEH
ASQQFFTISQAGVKKKASPIKELVKTGIRMLENLRASQSSVTGVASGFSELDQFTAGFQPSDMIIIAARPSAGKTAFSLA
LARNAAVDFNTPVLFFSLEMAEVQLAIRLMCAEAYVESQLVRTGRITPEMMGRIINSMDKLNEAKLFIDDTPGISIMELA
AKTRRMKQEQNIGMVVVDYLQLVTPVRDGRTNREQEIAQISRSLKALAKELNIPIIALAQLNRSVEQRSGDRRPQLSDLR
ESGSIEQDADVVMFLSRPEMYGKNTFEDGTSTKDIVEIVIGKQRNGPIGDIRLLFLKNYGRFQSTANVYITANAEAESAP
QAEPERYLQPSQEFPPPASGGAFIAQDDAPF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=455, Percent_Identity=43.7362637362637, Blast_Score=348, Evalue=7e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 57065; Mature: 57065

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKKAAPIIDFSKDIDFSQESRIPPYSTEVEQEVLACVLLEDEPIEQVIQIFGESSEEV
CCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHCCCHHHH
FYERRHQTIFRAMMQLYHKRQAIDIITVSEELLRMGELEVVGGRHYLAELSGKVISAANI
HHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHCCCEEEECCHHHHHHHCCCEEECCCH
EYYARLAKEKFLYRRLISIATKISGVAYNSSMDIFDLVEHASQQFFTISQAGVKKKASPI
HHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHEEEHHHHCCHHHHHHH
KELVKTGIRMLENLRASQSSVTGVASGFSELDQFTAGFQPSDMIIIAARPSAGKTAFSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LARNAAVDFNTPVLFFSLEMAEVQLAIRLMCAEAYVESQLVRTGRITPEMMGRIINSMDK
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LNEAKLFIDDTPGISIMELAAKTRRMKQEQNIGMVVVDYLQLVTPVRDGRTNREQEIAQI
HCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SRSLKALAKELNIPIIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSRPEM
HHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCC
YGKNTFEDGTSTKDIVEIVIGKQRNGPIGDIRLLFLKNYGRFQSTANVYITANAEAESAP
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCC
QAEPERYLQPSQEFPPPASGGAFIAQDDAPF
CCCCHHHCCCCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MISKKAAPIIDFSKDIDFSQESRIPPYSTEVEQEVLACVLLEDEPIEQVIQIFGESSEEV
CCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHEECCCCHHHHHHHHCCCHHHH
FYERRHQTIFRAMMQLYHKRQAIDIITVSEELLRMGELEVVGGRHYLAELSGKVISAANI
HHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHCCCEEEECCHHHHHHHCCCEEECCCH
EYYARLAKEKFLYRRLISIATKISGVAYNSSMDIFDLVEHASQQFFTISQAGVKKKASPI
HHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHEEEHHHHCCHHHHHHH
KELVKTGIRMLENLRASQSSVTGVASGFSELDQFTAGFQPSDMIIIAARPSAGKTAFSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LARNAAVDFNTPVLFFSLEMAEVQLAIRLMCAEAYVESQLVRTGRITPEMMGRIINSMDK
HHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LNEAKLFIDDTPGISIMELAAKTRRMKQEQNIGMVVVDYLQLVTPVRDGRTNREQEIAQI
HCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SRSLKALAKELNIPIIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADVVMFLSRPEM
HHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCC
YGKNTFEDGTSTKDIVEIVIGKQRNGPIGDIRLLFLKNYGRFQSTANVYITANAEAESAP
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCC
QAEPERYLQPSQEFPPPASGGAFIAQDDAPF
CCCCHHHCCCCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]