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The map label for this gene is hdrA2 [H]

Identifier: 78189544

GI number: 78189544

Start: 2068000

End: 2069238

Strand: Reverse

Name: hdrA2 [H]

Synonym: Cag_1584

Alternate gene names: 78189544

Gene position: 2069238-2068000 (Counterclockwise)

Preceding gene: 78189545

Following gene: 78189543

Centisome position: 80.45

GC content: 43.91

Gene sequence:

>1239_bases
ATGTCAGTTGAAACCATTGTAATCGTCGGCGGTGGCATCAGTGGAATTACCACAGCAGTTGAGGCTGCTGAAGTTGGCTA
TAACGTCATTCTTGTTGAGAAAAACGCTTACCTCGGTGGACGAGTAGCGCAGCTTAACAAGTATTTCCCCAAATTGTGCC
CCCCCTATTGCGGTCTTGAAATGAATTTCAGACGCATTAAGCTTAATCCGAAAATTACCGTTTATACCCTGACCGAGGTA
GAAAATGTAAGCGGCAAAGAGGGTGACTATAGCATTAAGCTTAAAGTCAATCCGCGCTATGTGAACGAAAAGTGTACAGC
GTGCAATGCCTGCGCAGAAGTATGCCCTGCGGAACGCTCTAACGACTTTAATTTTGGGATGAATAAAAGCAAGGCTATTT
ACTTGCCGCATGAGCTTGCTTATCCCACTAAATATGTAATTGATCGGAAAGCATGTGCCCAATCCTGCGACAAATGTGTT
AAGGCTTGTGTATATAATGCTATAGATTTAACCATGAAGCCTGAAACCGTTGAGGTAAAAGCTGGCAGCATTGTGTATGC
AACGGGCTGGAATCCTTACGATGCAACTAAAATGCAGAATTTGGGCTTTGGGCGTGTAAAAAATGTTATCACCAATATGA
TGATGGAGCGTTTAGCAGCGCCTAACGGTCCAACAGGTGGTAAAATTGTTCGTCCATCGGATGGGCGCGAAGTAAAAAAG
GTTGTTTTTGTGCAATGTGCAGGCTCTCGTGATCAAAACCACTTGAACTACTGTTCGGCTATTTGCTGTATGGCATCACT
CAAGCAAGCAACCTACATTCGCGATCGCTATCCTGATGCTGATATTATGATAGCCTATATTGATTTACGCACACCCGGTA
AGTATGAGGCGTTTTTAAATAAAGTTGAAAACGATAAACGCATTCGCTTAGTAAAAGGCAAAGTTGCGCAAATTGAAGAA
GATCGTGCTACAGGCAACGTTATTCTCACCTCAGAAGATGTTGAAGGTGGCGGCAAAAGTACTTATGAAGCCGATATGGT
AGTGCTTGCAACGGGTATGGCTCCATCGGTAAGCGATCATCCCATGCTTGCTTTTGAGCAAAATGGATTTATTCAGGGTG
GCAAAGCGGCTGGTATTTATTCTACCGGTGTAGCAAAACGTCCTTCTGATGTTACAACCTCTCTTCAGGACGCAACCGGC
GTCGCATTGAAAAGCATTCAAAGTTTGGTAAGGAGTTAA

Upstream 100 bases:

>100_bases
GATTGCTACTTAGTAGTGCAGCATCTATGTTGAATAATAGGAAGTCGCCATTCGGCTTTTTTAAGAACGATTTTTGATAG
TTTATCCGCAGAGGAACATC

Downstream 100 bases:

>100_bases
AACATGGCAGATGAAAAGAAAATTGGAGTGTATCTCTGTACCGGCTGCGGCATTGGTGAGGCGCTGAATATTGATGAGCT
TGAAGCTGTAGCTAAAAAAG

Product: heterodisulfide reductase, subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSVETIVIVGGGISGITTAVEAAEVGYNVILVEKNAYLGGRVAQLNKYFPKLCPPYCGLEMNFRRIKLNPKITVYTLTEV
ENVSGKEGDYSIKLKVNPRYVNEKCTACNACAEVCPAERSNDFNFGMNKSKAIYLPHELAYPTKYVIDRKACAQSCDKCV
KACVYNAIDLTMKPETVEVKAGSIVYATGWNPYDATKMQNLGFGRVKNVITNMMMERLAAPNGPTGGKIVRPSDGREVKK
VVFVQCAGSRDQNHLNYCSAICCMASLKQATYIRDRYPDADIMIAYIDLRTPGKYEAFLNKVENDKRIRLVKGKVAQIEE
DRATGNVILTSEDVEGGGKSTYEADMVVLATGMAPSVSDHPMLAFEQNGFIQGGKAAGIYSTGVAKRPSDVTTSLQDATG
VALKSIQSLVRS

Sequences:

>Translated_412_residues
MSVETIVIVGGGISGITTAVEAAEVGYNVILVEKNAYLGGRVAQLNKYFPKLCPPYCGLEMNFRRIKLNPKITVYTLTEV
ENVSGKEGDYSIKLKVNPRYVNEKCTACNACAEVCPAERSNDFNFGMNKSKAIYLPHELAYPTKYVIDRKACAQSCDKCV
KACVYNAIDLTMKPETVEVKAGSIVYATGWNPYDATKMQNLGFGRVKNVITNMMMERLAAPNGPTGGKIVRPSDGREVKK
VVFVQCAGSRDQNHLNYCSAICCMASLKQATYIRDRYPDADIMIAYIDLRTPGKYEAFLNKVENDKRIRLVKGKVAQIEE
DRATGNVILTSEDVEGGGKSTYEADMVVLATGMAPSVSDHPMLAFEQNGFIQGGKAAGIYSTGVAKRPSDVTTSLQDATG
VALKSIQSLVRS
>Mature_411_residues
SVETIVIVGGGISGITTAVEAAEVGYNVILVEKNAYLGGRVAQLNKYFPKLCPPYCGLEMNFRRIKLNPKITVYTLTEVE
NVSGKEGDYSIKLKVNPRYVNEKCTACNACAEVCPAERSNDFNFGMNKSKAIYLPHELAYPTKYVIDRKACAQSCDKCVK
ACVYNAIDLTMKPETVEVKAGSIVYATGWNPYDATKMQNLGFGRVKNVITNMMMERLAAPNGPTGGKIVRPSDGREVKKV
VFVQCAGSRDQNHLNYCSAICCMASLKQATYIRDRYPDADIMIAYIDLRTPGKYEAFLNKVENDKRIRLVKGKVAQIEED
RATGNVILTSEDVEGGGKSTYEADMVVLATGMAPSVSDHPMLAFEQNGFIQGGKAAGIYSTGVAKRPSDVTTSLQDATGV
ALKSIQSLVRS

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 44941; Mature: 44810

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVETIVIVGGGISGITTAVEAAEVGYNVILVEKNAYLGGRVAQLNKYFPKLCPPYCGLE
CCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
MNFRRIKLNPKITVYTLTEVENVSGKEGDYSIKLKVNPRYVNEKCTACNACAEVCPAERS
CCEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
NDFNFGMNKSKAIYLPHELAYPTKYVIDRKACAQSCDKCVKACVYNAIDLTMKPETVEVK
CCCCCCCCCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEE
AGSIVYATGWNPYDATKMQNLGFGRVKNVITNMMMERLAAPNGPTGGKIVRPSDGREVKK
CCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEE
VVFVQCAGSRDQNHLNYCSAICCMASLKQATYIRDRYPDADIMIAYIDLRTPGKYEAFLN
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHH
KVENDKRIRLVKGKVAQIEEDRATGNVILTSEDVEGGGKSTYEADMVVLATGMAPSVSDH
HCCCCCEEEEEECCHHHEECCCCCCCEEEEECCCCCCCCCCEECCEEEEEECCCCCCCCC
PMLAFEQNGFIQGGKAAGIYSTGVAKRPSDVTTSLQDATGVALKSIQSLVRS
CEEEEECCCCEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVETIVIVGGGISGITTAVEAAEVGYNVILVEKNAYLGGRVAQLNKYFPKLCPPYCGLE
CCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
MNFRRIKLNPKITVYTLTEVENVSGKEGDYSIKLKVNPRYVNEKCTACNACAEVCPAERS
CCEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
NDFNFGMNKSKAIYLPHELAYPTKYVIDRKACAQSCDKCVKACVYNAIDLTMKPETVEVK
CCCCCCCCCCCEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEE
AGSIVYATGWNPYDATKMQNLGFGRVKNVITNMMMERLAAPNGPTGGKIVRPSDGREVKK
CCEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEEE
VVFVQCAGSRDQNHLNYCSAICCMASLKQATYIRDRYPDADIMIAYIDLRTPGKYEAFLN
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHH
KVENDKRIRLVKGKVAQIEEDRATGNVILTSEDVEGGGKSTYEADMVVLATGMAPSVSDH
HCCCCCEEEEEECCHHHEECCCCCCCEEEEECCCCCCCCCCEECCEEEEEECCCCCCCCC
PMLAFEQNGFIQGGKAAGIYSTGVAKRPSDVTTSLQDATGVALKSIQSLVRS
CEEEEECCCCEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]