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The map label for this gene is aroC

Identifier: 78189479

GI number: 78189479

Start: 1994220

End: 1995419

Strand: Reverse

Name: aroC

Synonym: Cag_1519

Alternate gene names: 78189479

Gene position: 1995419-1994220 (Counterclockwise)

Preceding gene: 78189480

Following gene: 78189477

Centisome position: 77.58

GC content: 52.75

Gene sequence:

>1200_bases
ATGATACAATACGTTACGGCTGGTGAATCGCACGGACCAGCGCTTTCAGCCATTGTTGATGGAATGCCCGCAGGCGTTCC
CTTAACCGATGAAGCCATTAACCATCAATTAGCACGGCGCCAACAAGGTTACGGACGCGGTGGGCGCATGAAAATTGAAA
CCGACAAAGCCGAAGTACTTTCGGGCATTCGCTTCGGCAAAACCATTGGTTCGCCCATTGCTATGGTAATTCGCAATCGC
GATTGGCAAAATTGGACAACCACCATGGCGCAATTCGAGCAACCCCAAGAAGCCATTCCCGCCATTACCGTACCCCGCCC
CGGACACGCCGACCTTGCAGGCTGCATTAAATATGGCTTTGAAGATATTCGTCCCGTTATTGAACGCTCCTCCGCTCGCG
AAACTGCTGCCCGCGTTGCGGCTGGCGCTTGCGCTAAACTTTTCCTGAAAGCCCTTGGCATTGAAATTGGCTCCATTGTA
ACGGCTATTGGTTCGGCGAAAGAGGAGATGCCTCAGCAAGAACTTGCCGCCATGTTAGCTCACGGTGCCGAAGCGGTTGC
CACACAAGCCGACCAATCACCCGTGCGAATGCTCAGCAAAAGCGCCGAAACCGCCGCAATTGCCGCAATTGACGAAGCCA
AAGCCAATGGCGATACGGTAGGGGGAATTGTTGATGTGTTTATAACGGGCGTACCACTTGGCTTTGGAAGCTACGTACAG
CACAACCGTCGGCTTGATGCCGATTTAGCCGCTGCCTTGCTCTCCATTCAAGCCATTAAAGGCGTTGAAATTGGCACCGC
ATTTGACAATGCTTGCAAGTATGGTTCGCAAGTGCATGACGAATTTATTTTTTCAGAAAGCGGGGAACTCACGCGCCCAA
CCAACCGCGCAGGAGGTATTGAAGGGAGCATGTCGAGCGGACAAGTCATCCACCTACGCGCCGCCATGAAACCGATTTCA
TCCCTGATTTCACCATTGCAATCGTTTGATATTGCCTCAATGGAGCCCATTCCCTCTCGTTTTGAACGTAGCGATACCTG
CGCCGTACCTGCAGCAGGCGTTGTTGCTGAAGCCGTGGTTGCACCCGTTATTGCAAACGCCCTGCTTGCCAAGCTTGGTG
GCGACCACTTCAGCGAAATTCACGAACGTCTTGAAGCGTATCGAGCCTACCTTGCAAACCGCTTGCAGCGAAAGAGTTAA

Upstream 100 bases:

>100_bases
GATTTAATCGTGGTTATGCTCTTTTACGAAATTTTCTTATTTCTGGATTTCCGCTTGAGCGGGAATGACGAAAGAGAGTT
ACTCATGAATAATTCAGGTT

Downstream 100 bases:

>100_bases
CGGAAAAATATAAAAGGAAAGCGGACATTCGTGTCCGCTAACAAATAACTGCTGTTTTCCTGAATTAAGCCTATCTGTCG
GATTCCGTTAGGTTGTATGG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVLSGIRFGKTIGSPIAMVIRNR
DWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGFEDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIV
TAIGSAKEEMPQQELAAMLAHGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQ
HNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGIEGSMSSGQVIHLRAAMKPIS
SLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVVAPVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS

Sequences:

>Translated_399_residues
MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVLSGIRFGKTIGSPIAMVIRNR
DWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGFEDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIV
TAIGSAKEEMPQQELAAMLAHGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQ
HNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGIEGSMSSGQVIHLRAAMKPIS
SLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVVAPVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS
>Mature_399_residues
MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVLSGIRFGKTIGSPIAMVIRNR
DWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGFEDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIV
TAIGSAKEEMPQQELAAMLAHGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQ
HNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGIEGSMSSGQVIHLRAAMKPIS
SLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVVAPVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=374, Percent_Identity=39.3048128342246, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321290, Length=379, Percent_Identity=33.7730870712401, Blast_Score=187, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CHLCH (Q3AQF1)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379817.1
- HSSP:   P63611
- ProteinModelPortal:   Q3AQF1
- SMR:   Q3AQF1
- STRING:   Q3AQF1
- GeneID:   3747153
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1519
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   CCHL340177:CAG_1519-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42285; Mature: 42285

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVL
CCEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SGIRFGKTIGSPIAMVIRNRDWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGF
HHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCHHHHCCEEECCCCCCHHHHHHHHHCH
EDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIVTAIGSAKEEMPQQELAAMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHH
HGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQ
HCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
HNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGI
HCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EGSMSSGQVIHLRAAMKPISSLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVV
CCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHH
APVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQYVTAGESHGPALSAIVDGMPAGVPLTDEAINHQLARRQQGYGRGGRMKIETDKAEVL
CCEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SGIRFGKTIGSPIAMVIRNRDWQNWTTTMAQFEQPQEAIPAITVPRPGHADLAGCIKYGF
HHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCHHHHCCEEECCCCCCHHHHHHHHHCH
EDIRPVIERSSARETAARVAAGACAKLFLKALGIEIGSIVTAIGSAKEEMPQQELAAMLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHH
HGAEAVATQADQSPVRMLSKSAETAAIAAIDEAKANGDTVGGIVDVFITGVPLGFGSYVQ
HCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHH
HNRRLDADLAAALLSIQAIKGVEIGTAFDNACKYGSQVHDEFIFSESGELTRPTNRAGGI
HCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EGSMSSGQVIHLRAAMKPISSLISPLQSFDIASMEPIPSRFERSDTCAVPAAGVVAEAVV
CCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHH
APVIANALLAKLGGDHFSEIHERLEAYRAYLANRLQRKS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA