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The map label for this gene is fruA [H]

Identifier: 78189429

GI number: 78189429

Start: 1934171

End: 1934641

Strand: Reverse

Name: fruA [H]

Synonym: Cag_1468

Alternate gene names: 78189429

Gene position: 1934641-1934171 (Counterclockwise)

Preceding gene: 78189430

Following gene: 78189428

Centisome position: 75.22

GC content: 46.92

Gene sequence:

>471_bases
ATGAAAATAGAAAGCCTTCTTTCCGAATCCTATGTTGCCCTGAACCTTGAGTTGGTTCAAAAAAGTCAGGTGATTGCAAC
CATGCTCTCTATTGTAGAGCGCCATCCTGCCGTTAGCGACAATGTTAAACTACGCGCTGATGTGCTCAAGCGTGAGCAAG
AAATGTCCACCGGTATAGGTAAAAGCCTTGCGTTGCCCCATGCTAAAAGTGCGGCGGTTAGCCAACCGGTTATTGCTTTT
GCCACGTTAAAAAAAGCGTTGGATTTTGATTCCATTGATGGCGAACCAGTGCAAATTGTCTTTTTACTTGCCACTCCCGA
AGCCATGTTAGCCGAGCATTTAAAGCTGCTTGGGCGCATTACTCGTCTTGCAGGGCGCGAAGAGGTACGCCACAAGCTTT
TGCAGCTTCGTACCCCAGCCGAGGTTATTGCGCTTTTTAAGGAGGAGGAGAAAGATTTTCCTGAGATTTAA

Upstream 100 bases:

>100_bases
GGTGGGCTGTTTACTTGTTCATAAGCCACTTGTTCACGGAGCAAAATGCCAACAATCATGCCTTTTTGGTAGGCTAACAA
CCGCAGTAGGGTTGTGTATT

Downstream 100 bases:

>100_bases
ATCAACTGTATGTCAAGTTTTCAGTGCGTAAAAGGTACTCGCGATATTTTGCCCGACGAGAGCCTTCTTTGGTCGTTTGT
GTCATCCCATTTTCATCATG

Product: putative PTS IIA-like nitrogen-regulatory protein PtsN

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKIESLLSESYVALNLELVQKSQVIATMLSIVERHPAVSDNVKLRADVLKREQEMSTGIGKSLALPHAKSAAVSQPVIAF
ATLKKALDFDSIDGEPVQIVFLLATPEAMLAEHLKLLGRITRLAGREEVRHKLLQLRTPAEVIALFKEEEKDFPEI

Sequences:

>Translated_156_residues
MKIESLLSESYVALNLELVQKSQVIATMLSIVERHPAVSDNVKLRADVLKREQEMSTGIGKSLALPHAKSAAVSQPVIAF
ATLKKALDFDSIDGEPVQIVFLLATPEAMLAEHLKLLGRITRLAGREEVRHKLLQLRTPAEVIALFKEEEKDFPEI
>Mature_156_residues
MKIESLLSESYVALNLELVQKSQVIATMLSIVERHPAVSDNVKLRADVLKREQEMSTGIGKSLALPHAKSAAVSQPVIAF
ATLKKALDFDSIDGEPVQIVFLLATPEAMLAEHLKLLGRITRLAGREEVRHKLLQLRTPAEVIALFKEEEKDFPEI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367327, Length=142, Percent_Identity=30.9859154929577, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1786951, Length=151, Percent_Identity=27.8145695364238, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17293; Mature: 17293

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIESLLSESYVALNLELVQKSQVIATMLSIVERHPAVSDNVKLRADVLKREQEMSTGIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
KSLALPHAKSAAVSQPVIAFATLKKALDFDSIDGEPVQIVFLLATPEAMLAEHLKLLGRI
CHHCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHH
TRLAGREEVRHKLLQLRTPAEVIALFKEEEKDFPEI
HHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIESLLSESYVALNLELVQKSQVIATMLSIVERHPAVSDNVKLRADVLKREQEMSTGIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
KSLALPHAKSAAVSQPVIAFATLKKALDFDSIDGEPVQIVFLLATPEAMLAEHLKLLGRI
CHHCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHH
TRLAGREEVRHKLLQLRTPAEVIALFKEEEKDFPEI
HHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]