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The map label for this gene is hrcA

Identifier: 78189387

GI number: 78189387

Start: 1893393

End: 1894439

Strand: Reverse

Name: hrcA

Synonym: Cag_1424

Alternate gene names: 78189387

Gene position: 1894439-1893393 (Counterclockwise)

Preceding gene: 78189388

Following gene: 78189386

Centisome position: 73.65

GC content: 44.32

Gene sequence:

>1047_bases
ATGGATTATCGTGAACTAACAGCAAGAGAACGCCAAATACTGGGGATTATTATTCAATCCTACGTAGTAAGCGCTGCACC
TGTTGGCTCTAAATATATTGCCCGCCATTACAATCTTGGGCTTTCCGACGCTACCATTCGCAATGTTATGGCAGAGCTTG
AGGAGCTTGGTTTTATTAGCCAACCGCACACTTCCGCCGGACGAGTGCCAACCGATAAGGGTTACCGTTATTATGTTGAT
TTGATTATGACGGTTAAAACGCTTGATGAACAGGAAAAGCAACGATTTGAGCAACATATTACACCGCTTGAGCGCAAAGG
TACTTCGGCTGATGTATTGCTTTCAGCCGTAAAGGTGCTCGGCACTATTTCGCGCCAACTAAGCGTTGTGCTTTCGCCAA
CATTATCGAATGCACTTTTTGAAAAGCTTGATATGGTGCTACTGAGTTCAACCCGCATGATGGTTATTATCTCAATTCAA
TCGCTTTTTGTAAAGACGATTGTAATGGAGTTACACATGCAGGTGTCGCGCCAAATGTTGGATGAAGTGGTTGATGTACT
GAATGAGCGATTATCGGGGCTAACGCTTTCTGAAATTCGTCGCTCTATTAATCAGCGCCTTGCCGATTGTTCGTGCGATA
ATGAGTTGAAAAACCTTATTGTACGTTCGGCGGGAACTCTTTTTGATGAAATGCCCGTTTTTGAAAGGCTTTACATTTCG
GGCACTGAATATTTGGTAGAACAACCCGAGTTTCAACAGCCTGAAAAGGTGCGCGATCTCATTACTATGCTCGAAGATAA
ATTTAGTGTTGCAACCTTAGTGGAGCAACATCATGCCAACAACCCCGATGTAACTATCACCATTGGCAAAGAGCATGGTA
AGCGGCAGGCGGAGGATTTAACCGTTCTTTCTGCCCCATATTATGTGGGCGATATGGTAGGAACGGTTGGCATTCTTGGA
CCAAAGCGCATGGATTATGAACATGCCGTGCGCATTTTGCACTACATGGCAGGAAGTTTATCCTCCACCTTATCAATTCA
GAACTAA

Upstream 100 bases:

>100_bases
TATTACGGCGCGCAAGAGCGAAAAAAGCTAACTGCTGGAATACCATTGATTTTTTTAAATTCAGCGCTTATTGGTTTTTA
ACTTAATAAAAAGAGATGTA

Downstream 100 bases:

>100_bases
GATTTTTTTACTCACTAACATTGTGGGCAATCGTTTTCATACATGAAAAAACGCTTATTACGAAATCTTTTCACCAAACA
ACATACTATGGACAATATAC

Product: negative regulator of class I heat shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFISQPHTSAGRVPTDKGYRYYVD
LIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVLGTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQ
SLFVKTIVMELHMQVSRQMLDEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYIS
GTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDLTVLSAPYYVGDMVGTVGILG
PKRMDYEHAVRILHYMAGSLSSTLSIQN

Sequences:

>Translated_348_residues
MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFISQPHTSAGRVPTDKGYRYYVD
LIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVLGTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQ
SLFVKTIVMELHMQVSRQMLDEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYIS
GTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDLTVLSAPYYVGDMVGTVGILG
PKRMDYEHAVRILHYMAGSLSSTLSIQN
>Mature_348_residues
MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFISQPHTSAGRVPTDKGYRYYVD
LIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVLGTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQ
SLFVKTIVMELHMQVSRQMLDEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYIS
GTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDLTVLSAPYYVGDMVGTVGILG
PKRMDYEHAVRILHYMAGSLSSTLSIQN

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_CHLCH (Q3AQP3)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379725.1
- ProteinModelPortal:   Q3AQP3
- SMR:   Q3AQP3
- STRING:   Q3AQP3
- GeneID:   3746317
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1424
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   CLSK637786
- BioCyc:   CCHL340177:CAG_1424-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 39225; Mature: 39225

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFIS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
QPHTSAGRVPTDKGYRYYVDLIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
GTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQSLFVKTIVMELHMQVSRQML
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYIS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHC
GTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDL
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCC
TVLSAPYYVGDMVGTVGILGPKRMDYEHAVRILHYMAGSLSSTLSIQN
EEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDYRELTARERQILGIIIQSYVVSAAPVGSKYIARHYNLGLSDATIRNVMAELEELGFIS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCC
QPHTSAGRVPTDKGYRYYVDLIMTVKTLDEQEKQRFEQHITPLERKGTSADVLLSAVKVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHH
GTISRQLSVVLSPTLSNALFEKLDMVLLSSTRMMVIISIQSLFVKTIVMELHMQVSRQML
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DEVVDVLNERLSGLTLSEIRRSINQRLADCSCDNELKNLIVRSAGTLFDEMPVFERLYIS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHC
GTEYLVEQPEFQQPEKVRDLITMLEDKFSVATLVEQHHANNPDVTITIGKEHGKRQAEDL
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHCC
TVLSAPYYVGDMVGTVGILGPKRMDYEHAVRILHYMAGSLSSTLSIQN
EEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA