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The map label for this gene is silC [H]

Identifier: 78189165

GI number: 78189165

Start: 1592849

End: 1594327

Strand: Reverse

Name: silC [H]

Synonym: Cag_1198

Alternate gene names: 78189165

Gene position: 1594327-1592849 (Counterclockwise)

Preceding gene: 78189166

Following gene: 78189162

Centisome position: 61.99

GC content: 51.39

Gene sequence:

>1479_bases
ATGAAGAGACATCCCAACGAAACAGGGGAAAATGACATTGTGCCCCAAATAACATGGTTTCCAACTATTATGCCTCATAC
AAAAAAGAAAACACGCTTGTTGCTTGCTGCAACGCAGTTAGCAATAGCAACAACCATTGTGGGATGTAGTGCTCCAAAAG
AGAGTATGCCGCCCGATGTTGCTATGCCTGATGCCTATCGAGGTGCGGCTACTGTGGCAGCGCCCTCTGATAGCACCATA
GCGCAAATGCCGTACCAAAACTTTTTTGCTGACACCGCACTCACGGCGCTCATTGAACAAACGCTTGCTCACAATGCGGA
TCTTCAATCAGCCCTCAAAAACATTGAGCTTGCCGAGCAAACCCTTGATGCCGCTAAAGTGGTGTGGCTCCCTTCGCTAA
ACCTCAGTGCCCAAACCATCCGCAATGAGTCCTCCGAACATGGAGTGCGCCGCACGCCCAAAGAGTTCACGGCAGCCGTT
TCCGCTTCGTGGGAAGTTGATGTGTGGGGAAAAATTAAAAATCGCAAACAGTCGGTGCTTGCCAACTACCTGAAAAGCCA
AGAGGCGGTAAAAGCGCTTAAAACGCGCCTTGTGGCAGATGTGGCAAGTGGCTATTACAACCTTCTTATGTTGGACGAGC
AACTTGCCGTTGCCCGCAAAAATCTTGCGCTTGCCGACAAAACGCTTGCGATGATGCAGCTTCAATATCAAGCAGGGCAA
TTCACCCACCTTGCTATTCGCCAGCAAGAAGCCGCACGCCAGCAACTTGCAGCCACCATTCCCCAAATTGAGCAAGCTGT
TGCCGTGCAAGAAAATGCCCTCAGCGTGCTCAGTGGATCCATGCCAAACGCTATTACACGTAATCCATCACTTTTGCAAG
TAAAGCCCACAAACACTTTTGCTGTAGGCATTCCCGCTGCAATGCTGCACAACCGCCCCGACGTGCAAGCGGCAGAATTT
GCCCTAAAAGCTGCAACTGCCGACATGAAAGAGTCGGGCGCCGCCTTTTACCCCAGCTTTACCATTACTGCGCAAAAAGG
GGTTAGCGCCCTGCAATCAAGCGACTGGTTCAATGTGCCAAGCTCACTCTTTAGCGTGGTGCAAGGCACTATGCTTCAGC
CAATTTTTCAGCGTGGGCAATTAGAGGTTACCTACAAGCAATCGCAAGTAAAGCGCGACCAAGCAGCTCTTGCCTTTCGC
CAATCGGTGGTGAAAGCGGTTGCCGAAGTCTCCGATGCACTTGTGCGCATTGAAAAGCTGCAAACGCAAGAACAGCTTGC
CGAAGAGCGCGTAGCCACGTTGCAACAAGCGGTGCGTAACGCCGATATGCTTTTTCGGAGTGGCTTAGCTACTTACGTGG
AGGTAATGAGCGTGCAAAGCAATGCGCATAATGCCGAGCTAACGCTTGCCGACCTACGCCGTCAACGCCTTACGGCAACC
GCTGAATTATATCGTGCTCTTGGTGGTGGGTGGAGGTAA

Upstream 100 bases:

>100_bases
TGGACAACGCTCTGAAGGATTGTTAAAAGAAGAAGCTGTCGGCATTGAGGTCAGCAAGAACGGCGATAACTTGCGTGACA
AACCAACGCCTCTCTGGAAA

Downstream 100 bases:

>100_bases
AGTGTTGATTATGAATTTTGAATTATAGATTTTTGATTGGATTGAGCAACAAAATATGATGCAATATCAGCCAGCACATC
ATCGGAAATAGTAAACTAAC

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MKRHPNETGENDIVPQITWFPTIMPHTKKKTRLLLAATQLAIATTIVGCSAPKESMPPDVAMPDAYRGAATVAAPSDSTI
AQMPYQNFFADTALTALIEQTLAHNADLQSALKNIELAEQTLDAAKVVWLPSLNLSAQTIRNESSEHGVRRTPKEFTAAV
SASWEVDVWGKIKNRKQSVLANYLKSQEAVKALKTRLVADVASGYYNLLMLDEQLAVARKNLALADKTLAMMQLQYQAGQ
FTHLAIRQQEAARQQLAATIPQIEQAVAVQENALSVLSGSMPNAITRNPSLLQVKPTNTFAVGIPAAMLHNRPDVQAAEF
ALKAATADMKESGAAFYPSFTITAQKGVSALQSSDWFNVPSSLFSVVQGTMLQPIFQRGQLEVTYKQSQVKRDQAALAFR
QSVVKAVAEVSDALVRIEKLQTQEQLAEERVATLQQAVRNADMLFRSGLATYVEVMSVQSNAHNAELTLADLRRQRLTAT
AELYRALGGGWR

Sequences:

>Translated_492_residues
MKRHPNETGENDIVPQITWFPTIMPHTKKKTRLLLAATQLAIATTIVGCSAPKESMPPDVAMPDAYRGAATVAAPSDSTI
AQMPYQNFFADTALTALIEQTLAHNADLQSALKNIELAEQTLDAAKVVWLPSLNLSAQTIRNESSEHGVRRTPKEFTAAV
SASWEVDVWGKIKNRKQSVLANYLKSQEAVKALKTRLVADVASGYYNLLMLDEQLAVARKNLALADKTLAMMQLQYQAGQ
FTHLAIRQQEAARQQLAATIPQIEQAVAVQENALSVLSGSMPNAITRNPSLLQVKPTNTFAVGIPAAMLHNRPDVQAAEF
ALKAATADMKESGAAFYPSFTITAQKGVSALQSSDWFNVPSSLFSVVQGTMLQPIFQRGQLEVTYKQSQVKRDQAALAFR
QSVVKAVAEVSDALVRIEKLQTQEQLAEERVATLQQAVRNADMLFRSGLATYVEVMSVQSNAHNAELTLADLRRQRLTAT
AELYRALGGGWR
>Mature_492_residues
MKRHPNETGENDIVPQITWFPTIMPHTKKKTRLLLAATQLAIATTIVGCSAPKESMPPDVAMPDAYRGAATVAAPSDSTI
AQMPYQNFFADTALTALIEQTLAHNADLQSALKNIELAEQTLDAAKVVWLPSLNLSAQTIRNESSEHGVRRTPKEFTAAV
SASWEVDVWGKIKNRKQSVLANYLKSQEAVKALKTRLVADVASGYYNLLMLDEQLAVARKNLALADKTLAMMQLQYQAGQ
FTHLAIRQQEAARQQLAATIPQIEQAVAVQENALSVLSGSMPNAITRNPSLLQVKPTNTFAVGIPAAMLHNRPDVQAAEF
ALKAATADMKESGAAFYPSFTITAQKGVSALQSSDWFNVPSSLFSVVQGTMLQPIFQRGQLEVTYKQSQVKRDQAALAFR
QSVVKAVAEVSDALVRIEKLQTQEQLAEERVATLQQAVRNADMLFRSGLATYVEVMSVQSNAHNAELTLADLRRQRLTAT
AELYRALGGGWR

Specific function: Component of the sil cation-efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=455, Percent_Identity=27.4725274725275, Blast_Score=168, Evalue=9e-43,
Organism=Escherichia coli, GI2367348, Length=493, Percent_Identity=24.1379310344828, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53814; Mature: 53814

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHPNETGENDIVPQITWFPTIMPHTKKKTRLLLAATQLAIATTIVGCSAPKESMPPDV
CCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMPDAYRGAATVAAPSDSTIAQMPYQNFFADTALTALIEQTLAHNADLQSALKNIELAEQ
CCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TLDAAKVVWLPSLNLSAQTIRNESSEHGVRRTPKEFTAAVSASWEVDVWGKIKNRKQSVL
HHHHHHEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHH
ANYLKSQEAVKALKTRLVADVASGYYNLLMLDEQLAVARKNLALADKTLAMMQLQYQAGQ
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTHLAIRQQEAARQQLAATIPQIEQAVAVQENALSVLSGSMPNAITRNPSLLQVKPTNTF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEE
AVGIPAAMLHNRPDVQAAEFALKAATADMKESGAAFYPSFTITAQKGVSALQSSDWFNVP
EECCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEHHHHHHHHHCCCCCCCH
SSLFSVVQGTMLQPIFQRGQLEVTYKQSQVKRDQAALAFRQSVVKAVAEVSDALVRIEKL
HHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQEQLAEERVATLQQAVRNADMLFRSGLATYVEVMSVQSNAHNAELTLADLRRQRLTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
AELYRALGGGWR
HHHHHHHCCCCC
>Mature Secondary Structure
MKRHPNETGENDIVPQITWFPTIMPHTKKKTRLLLAATQLAIATTIVGCSAPKESMPPDV
CCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMPDAYRGAATVAAPSDSTIAQMPYQNFFADTALTALIEQTLAHNADLQSALKNIELAEQ
CCCCCCCCCEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TLDAAKVVWLPSLNLSAQTIRNESSEHGVRRTPKEFTAAVSASWEVDVWGKIKNRKQSVL
HHHHHHEEEECCCCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHH
ANYLKSQEAVKALKTRLVADVASGYYNLLMLDEQLAVARKNLALADKTLAMMQLQYQAGQ
HHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTHLAIRQQEAARQQLAATIPQIEQAVAVQENALSVLSGSMPNAITRNPSLLQVKPTNTF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEE
AVGIPAAMLHNRPDVQAAEFALKAATADMKESGAAFYPSFTITAQKGVSALQSSDWFNVP
EECCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCEEEEHHHHHHHHHCCCCCCCH
SSLFSVVQGTMLQPIFQRGQLEVTYKQSQVKRDQAALAFRQSVVKAVAEVSDALVRIEKL
HHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQEQLAEERVATLQQAVRNADMLFRSGLATYVEVMSVQSNAHNAELTLADLRRQRLTAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
AELYRALGGGWR
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]