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The map label for this gene is hflX [H]

Identifier: 78189141

GI number: 78189141

Start: 1567867

End: 1569162

Strand: Reverse

Name: hflX [H]

Synonym: Cag_1174

Alternate gene names: 78189141

Gene position: 1569162-1567867 (Counterclockwise)

Preceding gene: 78189149

Following gene: 78189140

Centisome position: 61.01

GC content: 46.3

Gene sequence:

>1296_bases
TTGAATACTGTTACTCCTGAAAACCAACGCGAAAAAGCCTTTTTAGTTGGTATTTACTCCCCGCCTGAAGTGCCTCGCTC
CTTAGTTGAAGAGTATCTTGCTGAGTTGGCATTTTTAGCCGATACGGCAGGTGCCGATGTGCTTGATACCTTTATTCAAG
AGCGTAAAGTGCGCGATCCATCGTATTGCATTGGGCGTGGCAAGGTTGATGAAATGGAGGCGTACATTAAGTCTGAAAAG
ATTGATGTGGTGATTTTTGATGATGACCTTTCACCCGGGCAGGCACGCAATCTTGAGCGGGCGTGGGGATGCAAGGTGAT
TGATCGCACGGGATTGATTTTGCACATTTTTGCTATTCGCGCCCAATCCACACAAGCAAAAATGCAGGTGGAACTTGCTC
AGCTTGAGTACATTTTACCTCGTCTTTCAGGGGCGTGGACGCACCTTTCAAAGCAAAAAGGTGGCATTGGCAATAAAGGT
CCTGGTGAAACCCAAATTGAAACTGATCGCCGTTTAGTTCGTAACCGTATTGCTCTTTTAAAAAAGAAGTTACGTGAGGT
TGAGCGGCAGCATTATACCCGTACTCGTAGTCGCCAAAATGTCTCTCGTGTTTCGCTGGTGGGCTACACGAATGCAGGCA
AATCAACGCTGATGAATGCGCTCTGCCCGCAAGCCGAAGCTTTTGCAGAGAATCGCCTTTTTGCTACGCTTGATACCAAA
ACCCGTCGGCTTGAGTTAAAAATCAACAAGTTGGTGCTGCTTTCCGATACCGTAGGCTTTATCCGCAAACTCCCTCACAC
ATTGGTAGAGAGCTTTAAATCCACGCTTGACGAAGTGTTGCAAGCCGATTTTTTGCTGCATGTTATTGATATTAGCCATC
CAAGCTTTGAAGAGCAAATTGCCGTTGTGCGCGACACCTTACGTGAAATTGGTGTTCAGCACGATCAAATTATTGAAGTT
TTTAATAAAATTGATGCCCTTGAAGAGCCAACGCTTTTGCGCGAAATGGGCGACAAATATCCCAACGCTGTTTTTATTTC
AGCCGTGCGAGGTATTAATCTCTCCCTTTTAAAGGAGATTATTGGCGAGCAACTTGCACGCGACTACACCGAGCGCCATG
TGCGTTTGCATGTTTCCAACTACCGCTTAATTAGCTACCTCTACGACCACACCGAAGTGGTGGAAAAAAAGCATGAGGAT
GAAATGGTGGAATTAACCATTCATGTGCGGAACCATCAATTGCCTCAGATTGATGCTATGATTCAAGCGGCAGCAGAGGC
GCCCCATGAGCCTTGA

Upstream 100 bases:

>100_bases
GCGCCATTGCAAGCCGTCAAGATAAAATAATGGCTTCAATATCGCAATGCAGCAAAATTACGCAGCTTTATTTTTCTCAC
CTTCTCATCTTACTTGTTGA

Downstream 100 bases:

>100_bases
GCTATGCAATAGCACTCGCCAAGCTATTCCCAACAAACGCTTACTACAAGCCATTCGCATGGTTGTGCAAGGCGAAGGTT
ACGAAATTGCTACAATTACG

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNTVTPENQREKAFLVGIYSPPEVPRSLVEEYLAELAFLADTAGADVLDTFIQERKVRDPSYCIGRGKVDEMEAYIKSEK
IDVVIFDDDLSPGQARNLERAWGCKVIDRTGLILHIFAIRAQSTQAKMQVELAQLEYILPRLSGAWTHLSKQKGGIGNKG
PGETQIETDRRLVRNRIALLKKKLREVERQHYTRTRSRQNVSRVSLVGYTNAGKSTLMNALCPQAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDISHPSFEEQIAVVRDTLREIGVQHDQIIEV
FNKIDALEEPTLLREMGDKYPNAVFISAVRGINLSLLKEIIGEQLARDYTERHVRLHVSNYRLISYLYDHTEVVEKKHED
EMVELTIHVRNHQLPQIDAMIQAAAEAPHEP

Sequences:

>Translated_431_residues
MNTVTPENQREKAFLVGIYSPPEVPRSLVEEYLAELAFLADTAGADVLDTFIQERKVRDPSYCIGRGKVDEMEAYIKSEK
IDVVIFDDDLSPGQARNLERAWGCKVIDRTGLILHIFAIRAQSTQAKMQVELAQLEYILPRLSGAWTHLSKQKGGIGNKG
PGETQIETDRRLVRNRIALLKKKLREVERQHYTRTRSRQNVSRVSLVGYTNAGKSTLMNALCPQAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDISHPSFEEQIAVVRDTLREIGVQHDQIIEV
FNKIDALEEPTLLREMGDKYPNAVFISAVRGINLSLLKEIIGEQLARDYTERHVRLHVSNYRLISYLYDHTEVVEKKHED
EMVELTIHVRNHQLPQIDAMIQAAAEAPHEP
>Mature_431_residues
MNTVTPENQREKAFLVGIYSPPEVPRSLVEEYLAELAFLADTAGADVLDTFIQERKVRDPSYCIGRGKVDEMEAYIKSEK
IDVVIFDDDLSPGQARNLERAWGCKVIDRTGLILHIFAIRAQSTQAKMQVELAQLEYILPRLSGAWTHLSKQKGGIGNKG
PGETQIETDRRLVRNRIALLKKKLREVERQHYTRTRSRQNVSRVSLVGYTNAGKSTLMNALCPQAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDISHPSFEEQIAVVRDTLREIGVQHDQIIEV
FNKIDALEEPTLLREMGDKYPNAVFISAVRGINLSLLKEIIGEQLARDYTERHVRLHVSNYRLISYLYDHTEVVEKKHED
EMVELTIHVRNHQLPQIDAMIQAAAEAPHEP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=252, Percent_Identity=35.7142857142857, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310133116, Length=252, Percent_Identity=35.7142857142857, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI310124269, Length=244, Percent_Identity=36.0655737704918, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124267, Length=244, Percent_Identity=36.0655737704918, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124171, Length=244, Percent_Identity=36.0655737704918, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI310124169, Length=244, Percent_Identity=36.0655737704918, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1790615, Length=412, Percent_Identity=44.1747572815534, Blast_Score=299, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17561038, Length=315, Percent_Identity=30.7936507936508, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24650079, Length=365, Percent_Identity=31.2328767123288, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49148; Mature: 49148

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVTPENQREKAFLVGIYSPPEVPRSLVEEYLAELAFLADTAGADVLDTFIQERKVRDP
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
SYCIGRGKVDEMEAYIKSEKIDVVIFDDDLSPGQARNLERAWGCKVIDRTGLILHIFAIR
CCEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHCCEEECCCCCEEEHHHHH
AQSTQAKMQVELAQLEYILPRLSGAWTHLSKQKGGIGNKGPGETQIETDRRLVRNRIALL
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKKLREVERQHYTRTRSRQNVSRVSLVGYTNAGKSTLMNALCPQAEAFAENRLFATLDTK
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDISHPSFEEQI
CEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
AVVRDTLREIGVQHDQIIEVFNKIDALEEPTLLREMGDKYPNAVFISAVRGINLSLLKEI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEHHHHCCCHHHHHHH
IGEQLARDYTERHVRLHVSNYRLISYLYDHTEVVEKKHEDEMVELTIHVRNHQLPQIDAM
HHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHH
IQAAAEAPHEP
HHHHHCCCCCC
>Mature Secondary Structure
MNTVTPENQREKAFLVGIYSPPEVPRSLVEEYLAELAFLADTAGADVLDTFIQERKVRDP
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
SYCIGRGKVDEMEAYIKSEKIDVVIFDDDLSPGQARNLERAWGCKVIDRTGLILHIFAIR
CCEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHCCEEECCCCCEEEHHHHH
AQSTQAKMQVELAQLEYILPRLSGAWTHLSKQKGGIGNKGPGETQIETDRRLVRNRIALL
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKKLREVERQHYTRTRSRQNVSRVSLVGYTNAGKSTLMNALCPQAEAFAENRLFATLDTK
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHTLVESFKSTLDEVLQADFLLHVIDISHPSFEEQI
CEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHH
AVVRDTLREIGVQHDQIIEVFNKIDALEEPTLLREMGDKYPNAVFISAVRGINLSLLKEI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEHHHHCCCHHHHHHH
IGEQLARDYTERHVRLHVSNYRLISYLYDHTEVVEKKHEDEMVELTIHVRNHQLPQIDAM
HHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHH
IQAAAEAPHEP
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]