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The map label for this gene is 78189039

Identifier: 78189039

GI number: 78189039

Start: 1454547

End: 1455428

Strand: Reverse

Name: 78189039

Synonym: Cag_1072

Alternate gene names: NA

Gene position: 1455428-1454547 (Counterclockwise)

Preceding gene: 78189040

Following gene: 78189038

Centisome position: 56.59

GC content: 48.98

Gene sequence:

>882_bases
ATGATTGTTATGGCTGAAATTCGTATTGGGTCTCGAATGGTAGGTAACGGGCATCCCGTCTTTGTAATTGGGGAAATTGG
TATTAACCACAATGGCTCTCTTGAAAATGCCTTTAAATTGATTGAGGGTGCAGCACGAGCAGGATGCGATGCCGTAAAGT
TCCAAAAGCGCACGCCCGACCTTTGTGTGCCAAAAGATCAGCGCGATATTGAGCGCGACACCCCATGGGGGCGCATGAAG
TATATTGATTACCGTTATAAGGTTGAATTTGGTAAGGAGGAGTATGCTGCCATTGATGGTTGCTGTAAAGAGCATGGCAT
TGAGTGGTTTGCTTCGTGCTGGGATGAAGAGGCTGTGGATTTTATGGAACAATTCACTCCACCTTGCTATAAAGCCGCGT
CAGCATCCTTAACCGATTTACCGTTGTTAAAAAAGACCGCTACAACGGGTCGCTCGCTTATTATTTCTACGGGCATGTCC
ACCATGGAAGAGGTTGAGCGCACCGTTGCTGAATTGGGTATGGAGAAGCTCTTAATTGCGCACACCAATTCCACCTACCC
TTCGCCCATTGATGAACTCAATTTGCGTATGATCACCACGTTAAAAGCGCTCTATCCAGAGGTGCCCATTGGATACTCTG
GGCATGAAGTTGGGCTTGCTACAACGTGGGCAGCCGTAGCCTTGGGCGCAACGTTTGTAGAGCGCCACATTACGCTTGAC
CGTGCCATGTGGGGTTCCGACCAAGCGGCATCGGTAGAGCTTTCAGGGTTAGCAAAGTTGGTTGAAAATATTCGCGACAT
TGAAAAAGCGTTGGGCGATGGCGTTAAACGCTTGTATGAAGGCGAAGCGGCTGCCCGCAAGAAATTGCGCCGAACCTCTT
AG

Upstream 100 bases:

>100_bases
TAGCGCCTCTTTTTGAGAGCCTCTTTTAAAAAATTCTCCCTTTTTTTAACCTTAAACAAGGTGCGGCTTAAAGCGGCAAG
GCTTGTTTTATCTTCTTTTA

Downstream 100 bases:

>100_bases
TAATTTTTGATGGCGTAGGGGCAGATTCTATATCTGCCCTTCGTAAGGGCGAAAATGGATTTCGCCTCTACGGGGTGGTT
AATTTGGAGGCAGACTCATA

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MIVMAEIRIGSRMVGNGHPVFVIGEIGINHNGSLENAFKLIEGAARAGCDAVKFQKRTPDLCVPKDQRDIERDTPWGRMK
YIDYRYKVEFGKEEYAAIDGCCKEHGIEWFASCWDEEAVDFMEQFTPPCYKAASASLTDLPLLKKTATTGRSLIISTGMS
TMEEVERTVAELGMEKLLIAHTNSTYPSPIDELNLRMITTLKALYPEVPIGYSGHEVGLATTWAAVALGATFVERHITLD
RAMWGSDQAASVELSGLAKLVENIRDIEKALGDGVKRLYEGEAAARKKLRRTS

Sequences:

>Translated_293_residues
MIVMAEIRIGSRMVGNGHPVFVIGEIGINHNGSLENAFKLIEGAARAGCDAVKFQKRTPDLCVPKDQRDIERDTPWGRMK
YIDYRYKVEFGKEEYAAIDGCCKEHGIEWFASCWDEEAVDFMEQFTPPCYKAASASLTDLPLLKKTATTGRSLIISTGMS
TMEEVERTVAELGMEKLLIAHTNSTYPSPIDELNLRMITTLKALYPEVPIGYSGHEVGLATTWAAVALGATFVERHITLD
RAMWGSDQAASVELSGLAKLVENIRDIEKALGDGVKRLYEGEAAARKKLRRTS
>Mature_293_residues
MIVMAEIRIGSRMVGNGHPVFVIGEIGINHNGSLENAFKLIEGAARAGCDAVKFQKRTPDLCVPKDQRDIERDTPWGRMK
YIDYRYKVEFGKEEYAAIDGCCKEHGIEWFASCWDEEAVDFMEQFTPPCYKAASASLTDLPLLKKTATTGRSLIISTGMS
TMEEVERTVAELGMEKLLIAHTNSTYPSPIDELNLRMITTLKALYPEVPIGYSGHEVGLATTWAAVALGATFVERHITLD
RAMWGSDQAASVELSGLAKLVENIRDIEKALGDGVKRLYEGEAAARKKLRRTS

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=288, Percent_Identity=39.9305555555556, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI21357081, Length=256, Percent_Identity=39.84375, Blast_Score=183, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 32453; Mature: 32453

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVMAEIRIGSRMVGNGHPVFVIGEIGINHNGSLENAFKLIEGAARAGCDAVKFQKRTPD
CEEEEEEEECCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCC
LCVPKDQRDIERDTPWGRMKYIDYRYKVEFGKEEYAAIDGCCKEHGIEWFASCWDEEAVD
CCCCCCCHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCHHHHHHHCCHHHHH
FMEQFTPPCYKAASASLTDLPLLKKTATTGRSLIISTGMSTMEEVERTVAELGMEKLLIA
HHHHCCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCHHHEEEE
HTNSTYPSPIDELNLRMITTLKALYPEVPIGYSGHEVGLATTWAAVALGATFVERHITLD
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAMWGSDQAASVELSGLAKLVENIRDIEKALGDGVKRLYEGEAAARKKLRRTS
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MIVMAEIRIGSRMVGNGHPVFVIGEIGINHNGSLENAFKLIEGAARAGCDAVKFQKRTPD
CEEEEEEEECCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCC
LCVPKDQRDIERDTPWGRMKYIDYRYKVEFGKEEYAAIDGCCKEHGIEWFASCWDEEAVD
CCCCCCCHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHCHHHHHHHCCHHHHH
FMEQFTPPCYKAASASLTDLPLLKKTATTGRSLIISTGMSTMEEVERTVAELGMEKLLIA
HHHHCCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCHHHEEEE
HTNSTYPSPIDELNLRMITTLKALYPEVPIGYSGHEVGLATTWAAVALGATFVERHITLD
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAMWGSDQAASVELSGLAKLVENIRDIEKALGDGVKRLYEGEAAARKKLRRTS
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]