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The map label for this gene is htpG

Identifier: 78189038

GI number: 78189038

Start: 1452372

End: 1454261

Strand: Reverse

Name: htpG

Synonym: Cag_1071

Alternate gene names: 78189038

Gene position: 1454261-1452372 (Counterclockwise)

Preceding gene: 78189039

Following gene: 78189037

Centisome position: 56.54

GC content: 45.71

Gene sequence:

>1890_bases
ATGAGCAGTACCGAAAACAACGGCACCGCTGTGCCACTTCAAGAGTTTGAATACAAGGCTGAAATGAAGCAGCTTCTTGA
CTTAATTATTCACTCTCTTTATACCCATCCTGAAATTTATCTCAGGGAGCTTATTTCCAACGCCTCCGATGCTCTCAGCA
AAGCACGTTTTAATGCCCTTACCGATCAGGATATGCTCGATAAGGATGCCGAGCTTGCTATTCGCCTTACCTTAAATGCG
GAAGAAAAAAGCGTGGTGATTGAGGATAGCGGCATTGGTATGACCGAAGAGGAGCTGATTGCCAATCTTGGTACGGTGGC
AAAGTCGGGTACGCTTGGCTTTATGCAATCACTTAAAGAGCAACAGCAGCAGCTTGATGGCAATTTAATTGGGCAGTTTG
GTGTTGGCTTTTACTCGGTCTTTATGGTAACCGAAGAGGTTACGGTTGAAACCCGCAGCTTCCATTCCAATGCACAAGGT
TACCGCTGGCGTTCAAGTGGGCAAGGCACTTACACCATAGAGCAAATTGATAAAGCAACTCGTGGCACCCGTATCTCTTT
CAAATTAAAAGAGGAGCATCAAGAGTTTGCTGAAGAGTATCGTGTTGAGCAGATTATTAAGAAGTACTCCAACTTTGTGG
ATTTCCCCATCTACCTTGGCGAACGGCAGCTTAACAGCATGACTGCATTGTGGCAACGTCCAAAAAGTGAGCTGAAGGAT
GAGGAGGTCAACGAGTTCTACAAATTTGTAGCAAGTGACTTTAACGATCCGCTTGATTATCTCTCTATTTCGGTTGAAGG
TATGGTAAGCTTTAAAGCCTTGCTTTTCCTTCCAAAAGAGGCTCCCCCCGAATTGATGTATCGCCAAAGCGAGTTAGAAA
ATCGTGGACCGCAGCTTTACGTCAAAAAAGTACTCATTCAAAATGAGTGCCGCGACTTGCTGCCCGAATATCTCCGCTTT
ATTGCTGGTGTTGTGGATACTGAGGATTTGTCGCTCAACGTGTCGCGCGAAATGGTGCAATCAAGCCCTGTGATGGCAAA
AATCCGCCAAATTCTGACCGGTAAAATTCTTGGTTGGTTTGAAATGTTGGCTAAAGAGCAACCCGAGAAGTTCAAAACCT
TCTACAAAGCCTTTGGTCCCATCATTAAAATTGGGTTAAACACCGACTTCACCAATCGAGAGAAGCTCATTGAATTGCTC
CGCTTTGAGAGCACCAAAACCGAAGAGGGCGAATTTGTAACATTGCGCGAATACGTAGAGCGCATGGGTTCAGAACAAAA
AGAGATTTACTACCACTCAGGTAACAATCGCGCACAACTCTTAGCCCATCCCAACATTGAGTATTTCCGCGAACATGGCA
TTGAGGTACTGCTTTTAAGCGATCCGGTGGATATGTTTGTTATTCCCTCAATTCACGAGTTCGATAAAAAGCCGCTGAAA
TCTATTGAAAAGGCAGATTGCGACTTTTCACAGCAAAGCAGCAATAAAGCCGAACCGGTAGCGCCGAATTTGCTTAATCC
CGTGTTGCAAGCCTTTAAAGAGGCGCTCAGCAATGAAGTTGAAGATGTGGTGGAATCGCGCCGACTTGTTTCATCACCCG
TAACGTTGGTGAGCGGCAAAGATGCCATTGATAGCCAGCTTGAGCGCATGATGAAGATGATGAATACCCCAATGCCACCC
GCAAAGCGCATTTTAGAGGTGAACAGTTCGCATCCCATTGTTCGCAACATTGCAGGCATGATTATGGCAGATGCCAACAA
TCCGCTTATAAAAACCGTGGCGCGTCAACTCTACGAAGGAGCGCTCTTTCTTGAAGGCAGCCTTGAAGATGCGACCTCTT
ACGTAACACGCATGAATGAGTTAATTGAAGCGGCAACACTCACTCGTTAA

Upstream 100 bases:

>100_bases
GTTGTTTGCCAACGAGATTGTATAGAGACAACGCATGCGTTGTCTCTACGTGAAAAATTAGATTCTTTTCTTTCGTTAAC
GTTATTTCTGATAAACACTT

Downstream 100 bases:

>100_bases
CCGATATCAGTTGCCAAAAAAAGCCATCCCAAAGAGAAAAAATATGGGATGGCTTTTTTATTATGGGGAAATACTCCCGA
GAAATTTGGAAACAGAGGCT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MSSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNALTDQDMLDKDAELAIRLTLNA
EEKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKEQQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQG
YRWRSSGQGTYTIEQIDKATRGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKD
EEVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLYVKKVLIQNECRDLLPEYLRF
IAGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWFEMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELL
RFESTKTEEGEFVTLREYVERMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLK
SIEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGKDAIDSQLERMMKMMNTPMPP
AKRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEGALFLEGSLEDATSYVTRMNELIEAATLTR

Sequences:

>Translated_629_residues
MSSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNALTDQDMLDKDAELAIRLTLNA
EEKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKEQQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQG
YRWRSSGQGTYTIEQIDKATRGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKD
EEVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLYVKKVLIQNECRDLLPEYLRF
IAGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWFEMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELL
RFESTKTEEGEFVTLREYVERMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLK
SIEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGKDAIDSQLERMMKMMNTPMPP
AKRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEGALFLEGSLEDATSYVTRMNELIEAATLTR
>Mature_628_residues
SSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNALTDQDMLDKDAELAIRLTLNAE
EKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKEQQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQGY
RWRSSGQGTYTIEQIDKATRGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKDE
EVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLYVKKVLIQNECRDLLPEYLRFI
AGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWFEMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELLR
FESTKTEEGEFVTLREYVERMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLKS
IEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGKDAIDSQLERMMKMMNTPMPPA
KRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEGALFLEGSLEDATSYVTRMNELIEAATLTR

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI4507677, Length=676, Percent_Identity=33.5798816568047, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI155722983, Length=638, Percent_Identity=34.4827586206897, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=36.9565217391304, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI20149594, Length=414, Percent_Identity=36.9565217391304, Blast_Score=257, Evalue=3e-68,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=36.7149758454106, Blast_Score=254, Evalue=2e-67,
Organism=Escherichia coli, GI1786679, Length=626, Percent_Identity=39.776357827476, Blast_Score=466, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17559162, Length=666, Percent_Identity=36.1861861861862, Blast_Score=418, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17542208, Length=671, Percent_Identity=32.6378539493294, Blast_Score=348, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI115535205, Length=637, Percent_Identity=33.9089481946625, Blast_Score=342, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI115535167, Length=445, Percent_Identity=36.8539325842697, Blast_Score=283, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=36.4303178484108, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6323840, Length=409, Percent_Identity=36.1858190709046, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586016, Length=648, Percent_Identity=35.3395061728395, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI21357739, Length=668, Percent_Identity=34.7305389221557, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI17647529, Length=414, Percent_Identity=34.5410628019324, Blast_Score=244, Evalue=1e-64,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_CHLCH (Q3ARP2)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379376.1
- ProteinModelPortal:   Q3ARP2
- STRING:   Q3ARP2
- GeneID:   3746725
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1071
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   CCHL340177:CAG_1071-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71712; Mature: 71581

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
TDQDMLDKDAELAIRLTLNAEEKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKE
CCHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
QQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQGYRWRSSGQGTYTIEQIDKAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEHHHHHHHH
RGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKD
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHCCHHHCCH
EEVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
VKKVLIQNECRDLLPEYLRFIAGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHCCHHHHHHHHHHHHHHHHHH
EMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELLRFESTKTEEGEFVTLREYVE
HHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHH
RMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLK
HHCCCCCEEEEECCCCCEEEEECCCHHHHHHCCCEEEEEECCCCEEECCCHHHHCHHHHH
SIEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGK
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
DAIDSQLERMMKMMNTPMPPAKRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEG
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHEEECCCCHHHHHHHHHHHCC
ALFLEGSLEDATSYVTRMNELIEAATLTR
CEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSTENNGTAVPLQEFEYKAEMKQLLDLIIHSLYTHPEIYLRELISNASDALSKARFNAL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
TDQDMLDKDAELAIRLTLNAEEKSVVIEDSGIGMTEEELIANLGTVAKSGTLGFMQSLKE
CCHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
QQQQLDGNLIGQFGVGFYSVFMVTEEVTVETRSFHSNAQGYRWRSSGQGTYTIEQIDKAT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEHHHHHHHH
RGTRISFKLKEEHQEFAEEYRVEQIIKKYSNFVDFPIYLGERQLNSMTALWQRPKSELKD
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHCCHHHCCH
EEVNEFYKFVASDFNDPLDYLSISVEGMVSFKALLFLPKEAPPELMYRQSELENRGPQLY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHH
VKKVLIQNECRDLLPEYLRFIAGVVDTEDLSLNVSREMVQSSPVMAKIRQILTGKILGWF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHCCHHHHHHHHHHHHHHHHHH
EMLAKEQPEKFKTFYKAFGPIIKIGLNTDFTNREKLIELLRFESTKTEEGEFVTLREYVE
HHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHH
RMGSEQKEIYYHSGNNRAQLLAHPNIEYFREHGIEVLLLSDPVDMFVIPSIHEFDKKPLK
HHCCCCCEEEEECCCCCEEEEECCCHHHHHHCCCEEEEEECCCCEEECCCHHHHCHHHHH
SIEKADCDFSQQSSNKAEPVAPNLLNPVLQAFKEALSNEVEDVVESRRLVSSPVTLVSGK
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
DAIDSQLERMMKMMNTPMPPAKRILEVNSSHPIVRNIAGMIMADANNPLIKTVARQLYEG
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHEEECCCCHHHHHHHHHHHCC
ALFLEGSLEDATSYVTRMNELIEAATLTR
CEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA