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The map label for this gene is cobT

Identifier: 78189025

GI number: 78189025

Start: 1438984

End: 1440048

Strand: Reverse

Name: cobT

Synonym: Cag_1058

Alternate gene names: 78189025

Gene position: 1440048-1438984 (Counterclockwise)

Preceding gene: 78189026

Following gene: 78189024

Centisome position: 55.99

GC content: 49.39

Gene sequence:

>1065_bases
ATGAAAGAAAAATTAGAAACGTTATTGGCGGCAATTCAACCAGCCGATCAAACGTTGCGTCAGGCAATACAAGCGCATCT
TGACGATTTAACCAAACCGCAAGGTAGCCTTGGTCGCCTTGAGGAAATTGCACAGCAATATATTTTGGCTACAGGGCAAA
TTCATCCTTCCCTTCCCAAAAAGAAGATTTGTTGCTTTGCGGGCGATCATGGGGTGGCAGCCGAAGGTGTGTCGGCATTT
CCCGCTGAAGTAACGCCGCAAATGGTTTATAACATGCTGCATGGTGGTGCAGCAATTAATGTGCTGAGCCGTCATGTGGG
TGCCGAGCTATCGGTAGTTGATGTTGGGGTGAATCACGATTTTGCTGATGCACCAAATTTAGTGCAGTGCAAGGTAAAGC
GGGGCAGTGCCAATATGGCAGTTGGTGCAGCGATGAGCGAAACGGAGACGTTGCAGGCGATTTTAGCTGGTGCTGAATTG
GCGTTTCAAGCGGCAGATGCTGGCTATGGGTTGCTTGGCACGGGCGAAATGGGCATTGCAAACACAACTCCTGCAACTGC
TTTGTATGCCGTGTTATTGAATTTACCGGTTGAAGCTATTACAGGACGTGGCACGGGCATTGATGATGCTCGCTTGCACC
ATAAAATTGCGGTGATTGAACGAGCAATAGCCGTTAATGCAGAGCGTTGTGCAACGCCATTTGGTACGCTTGCGGCGCTT
GGTGGCTTTGAAATTGCAGCAATCACGGGCTTTATTCTTGGGGCAGCCGCTCGGCGCATTCCTGTGGTGGTTGATGGATT
TATTTCGTCATCGGGGGCATTGGTAGCTATGAAGATGGTGCCATCCGTGGTGGATTACTTATTCTTTAGCCACCTTTCAG
CCGAGCAAGGGCATGGTGCGGTAATGGAGGCGCTTGGCGTGCGCCCAATGCTTTCGCTTGATTTGCGTTTGGGTGAAGGA
ACTGGTGCAGCGCTTGCTATGCAGTTAGTGGATGCCGCGCTTAAAATTTATAATGAAATGGCAACCTTTAGTGGTGCTCA
AGTGAGTGAAAAAATTGAAGGATAG

Upstream 100 bases:

>100_bases
AGTGTTGAAGGATGGGTTGAAGGGGCAGGAGTTGGGTGAACATGCAATGTTTTAAGAAGCAGCGTTTCACATCATTTTAA
AAATATAGCAACCATATCGT

Downstream 100 bases:

>100_bases
GTTATGCTTGGTGGCTTAGTAACGGCGCTTCGTACTTTAACAATTTTGCCGATACCGGGGAAGGATGCTGTTACCTTTAG
TCATTCATTGTACTGGTTTC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKEKLETLLAAIQPADQTLRQAIQAHLDDLTKPQGSLGRLEEIAQQYILATGQIHPSLPKKKICCFAGDHGVAAEGVSAF
PAEVTPQMVYNMLHGGAAINVLSRHVGAELSVVDVGVNHDFADAPNLVQCKVKRGSANMAVGAAMSETETLQAILAGAEL
AFQAADAGYGLLGTGEMGIANTTPATALYAVLLNLPVEAITGRGTGIDDARLHHKIAVIERAIAVNAERCATPFGTLAAL
GGFEIAAITGFILGAAARRIPVVVDGFISSSGALVAMKMVPSVVDYLFFSHLSAEQGHGAVMEALGVRPMLSLDLRLGEG
TGAALAMQLVDAALKIYNEMATFSGAQVSEKIEG

Sequences:

>Translated_354_residues
MKEKLETLLAAIQPADQTLRQAIQAHLDDLTKPQGSLGRLEEIAQQYILATGQIHPSLPKKKICCFAGDHGVAAEGVSAF
PAEVTPQMVYNMLHGGAAINVLSRHVGAELSVVDVGVNHDFADAPNLVQCKVKRGSANMAVGAAMSETETLQAILAGAEL
AFQAADAGYGLLGTGEMGIANTTPATALYAVLLNLPVEAITGRGTGIDDARLHHKIAVIERAIAVNAERCATPFGTLAAL
GGFEIAAITGFILGAAARRIPVVVDGFISSSGALVAMKMVPSVVDYLFFSHLSAEQGHGAVMEALGVRPMLSLDLRLGEG
TGAALAMQLVDAALKIYNEMATFSGAQVSEKIEG
>Mature_354_residues
MKEKLETLLAAIQPADQTLRQAIQAHLDDLTKPQGSLGRLEEIAQQYILATGQIHPSLPKKKICCFAGDHGVAAEGVSAF
PAEVTPQMVYNMLHGGAAINVLSRHVGAELSVVDVGVNHDFADAPNLVQCKVKRGSANMAVGAAMSETETLQAILAGAEL
AFQAADAGYGLLGTGEMGIANTTPATALYAVLLNLPVEAITGRGTGIDDARLHHKIAVIERAIAVNAERCATPFGTLAAL
GGFEIAAITGFILGAAARRIPVVVDGFISSSGALVAMKMVPSVVDYLFFSHLSAEQGHGAVMEALGVRPMLSLDLRLGEG
TGAALAMQLVDAALKIYNEMATFSGAQVSEKIEG

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=346, Percent_Identity=39.5953757225434, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_CHLCH (Q3ARQ5)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_379363.1
- ProteinModelPortal:   Q3ARQ5
- SMR:   Q3ARQ5
- STRING:   Q3ARQ5
- GeneID:   3747041
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_1058
- eggNOG:   COG2038
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- BioCyc:   CCHL340177:CAG_1058-MONOMER
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 36763; Mature: 36763

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: ACT_SITE 319-319

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKLETLLAAIQPADQTLRQAIQAHLDDLTKPQGSLGRLEEIAQQYILATGQIHPSLPK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KKICCFAGDHGVAAEGVSAFPAEVTPQMVYNMLHGGAAINVLSRHVGAELSVVDVGVNHD
CCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
FADAPNLVQCKVKRGSANMAVGAAMSETETLQAILAGAELAFQAADAGYGLLGTGEMGIA
CCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCCC
NTTPATALYAVLLNLPVEAITGRGTGIDDARLHHKIAVIERAIAVNAERCATPFGTLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
GGFEIAAITGFILGAAARRIPVVVDGFISSSGALVAMKMVPSVVDYLFFSHLSAEQGHGA
CCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHH
VMEALGVRPMLSLDLRLGEGTGAALAMQLVDAALKIYNEMATFSGAQVSEKIEG
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MKEKLETLLAAIQPADQTLRQAIQAHLDDLTKPQGSLGRLEEIAQQYILATGQIHPSLPK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KKICCFAGDHGVAAEGVSAFPAEVTPQMVYNMLHGGAAINVLSRHVGAELSVVDVGVNHD
CCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCC
FADAPNLVQCKVKRGSANMAVGAAMSETETLQAILAGAELAFQAADAGYGLLGTGEMGIA
CCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCCCC
NTTPATALYAVLLNLPVEAITGRGTGIDDARLHHKIAVIERAIAVNAERCATPFGTLAAL
CCCHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
GGFEIAAITGFILGAAARRIPVVVDGFISSSGALVAMKMVPSVVDYLFFSHLSAEQGHGA
CCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHH
VMEALGVRPMLSLDLRLGEGTGAALAMQLVDAALKIYNEMATFSGAQVSEKIEG
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA