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The map label for this gene is ahpC [C]

Identifier: 78188676

GI number: 78188676

Start: 972916

End: 973506

Strand: Reverse

Name: ahpC [C]

Synonym: Cag_0700

Alternate gene names: 78188676

Gene position: 973506-972916 (Counterclockwise)

Preceding gene: 78188677

Following gene: 78188674

Centisome position: 37.85

GC content: 44.67

Gene sequence:

>591_bases
ATGAGTGTACTTGTAGGACGTAAAGCGCCTGAATTTGATGTTGCTGCCGTTGTTAATGGCTCACAGTTTGTTGACTCGTG
CAAACTCTCTGATTTTAAAGGAAAGTATGTGGTGCTCTTTTTCTATCCGCTTGACTTTACCTTTGTTTGCCCAACCGAGC
TTCACGCATTTCAAGAAAAAATTGAAGAGTTCAAAAAGCGCAATGTTGAAGTGCTTGGCTGCTCAATAGACTCAAAGTTT
TCACACTTTGCATGGTTGCGCACTCCCCGCTCGCAAGGCGGCATTGAAGGCGTAACTTATACGTTGCTTTCCGACATCAA
CAAAACGGTGGCGGCTGATTACGATGTGTTACTTGAAGATGAAGGCGTTGCGCTGAGAGGCTTATTCTTAATTGACCGCG
ATGGCGTTGTGCAGCATCAAGTAATAAACAATTTGTCGCTTGGGCGCAATGTGGACGAAGTGTTGCGATTAATTGATGCG
CTTCAGTTTACCGAAGAGTTTGGCGAAGTGTGCCCTGCAAACTGGAATAAAGGCGATAAAGCAATGAAGCCTACGCAAGG
CGGATTGGAAGAGTTTTATAAGGAAGGATAA

Upstream 100 bases:

>100_bases
TCTCAAAGCATTCCTTACTTTTGGCTTGCAAGAGAAATTCAAACCGCTTATATTGGGACAATTTTAATCCACAATTAATA
ACCCAAACCAAATAATTAAC

Downstream 100 bases:

>100_bases
GAAAGTGCTTTAGCGCACTGAGTTGCAAAAAAACTATATATAGCCGTACTGATGAAATGTATGCAATCAGTACGGCTATT
TTTGTTCACCCGATTCACTC

Product: thiolredoxin peroxidase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSVLVGRKAPEFDVAAVVNGSQFVDSCKLSDFKGKYVVLFFYPLDFTFVCPTELHAFQEKIEEFKKRNVEVLGCSIDSKF
SHFAWLRTPRSQGGIEGVTYTLLSDINKTVAADYDVLLEDEGVALRGLFLIDRDGVVQHQVINNLSLGRNVDEVLRLIDA
LQFTEEFGEVCPANWNKGDKAMKPTQGGLEEFYKEG

Sequences:

>Translated_196_residues
MSVLVGRKAPEFDVAAVVNGSQFVDSCKLSDFKGKYVVLFFYPLDFTFVCPTELHAFQEKIEEFKKRNVEVLGCSIDSKF
SHFAWLRTPRSQGGIEGVTYTLLSDINKTVAADYDVLLEDEGVALRGLFLIDRDGVVQHQVINNLSLGRNVDEVLRLIDA
LQFTEEFGEVCPANWNKGDKAMKPTQGGLEEFYKEG
>Mature_195_residues
SVLVGRKAPEFDVAAVVNGSQFVDSCKLSDFKGKYVVLFFYPLDFTFVCPTELHAFQEKIEEFKKRNVEVLGCSIDSKFS
HFAWLRTPRSQGGIEGVTYTLLSDINKTVAADYDVLLEDEGVALRGLFLIDRDGVVQHQVINNLSLGRNVDEVLRLIDAL
QFTEEFGEVCPANWNKGDKAMKPTQGGLEEFYKEG

Specific function: Reduces peroxides. May play an important role in eliminating peroxides generated during metabolism [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=52.8795811518325, Blast_Score=215, Evalue=2e-56,
Organism=Homo sapiens, GI32189392, Length=191, Percent_Identity=51.3089005235602, Blast_Score=215, Evalue=2e-56,
Organism=Homo sapiens, GI4505591, Length=192, Percent_Identity=52.6041666666667, Blast_Score=215, Evalue=2e-56,
Organism=Homo sapiens, GI32455266, Length=192, Percent_Identity=52.6041666666667, Blast_Score=215, Evalue=2e-56,
Organism=Homo sapiens, GI32455264, Length=192, Percent_Identity=52.6041666666667, Blast_Score=215, Evalue=2e-56,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=53.1914893617021, Blast_Score=214, Evalue=5e-56,
Organism=Homo sapiens, GI5453549, Length=189, Percent_Identity=47.6190476190476, Blast_Score=205, Evalue=2e-53,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=60.4938271604938, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI4758638, Length=190, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1786822, Length=183, Percent_Identity=35.5191256830601, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193204376, Length=192, Percent_Identity=52.6041666666667, Blast_Score=210, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI32565831, Length=192, Percent_Identity=52.6041666666667, Blast_Score=210, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17554494, Length=186, Percent_Identity=46.7741935483871, Blast_Score=187, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI25153706, Length=171, Percent_Identity=27.4853801169591, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=47.9381443298969, Blast_Score=192, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320661, Length=196, Percent_Identity=44.8979591836735, Blast_Score=181, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6319407, Length=196, Percent_Identity=34.1836734693878, Blast_Score=104, Evalue=8e-24,
Organism=Drosophila melanogaster, GI17738015, Length=185, Percent_Identity=55.1351351351351, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17157991, Length=188, Percent_Identity=52.6595744680851, Blast_Score=205, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24641739, Length=188, Percent_Identity=52.6595744680851, Blast_Score=205, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21357347, Length=192, Percent_Identity=48.9583333333333, Blast_Score=202, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=50.828729281768, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=50.828729281768, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24581278, Length=157, Percent_Identity=33.7579617834395, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17975518, Length=188, Percent_Identity=36.1702127659575, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24652434, Length=188, Percent_Identity=36.1702127659575, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24652436, Length=188, Percent_Identity=36.1702127659575, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21997; Mature: 21866

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVGRKAPEFDVAAVVNGSQFVDSCKLSDFKGKYVVLFFYPLDFTFVCPTELHAFQEK
CCEECCCCCCCCCEEEEECCHHHHHHCCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHH
IEEFKKRNVEVLGCSIDSKFSHFAWLRTPRSQGGIEGVTYTLLSDINKTVAADYDVLLED
HHHHHHCCEEEEEECCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
EGVALRGLFLIDRDGVVQHQVINNLSLGRNVDEVLRLIDALQFTEEFGEVCPANWNKGDK
CCCEEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AMKPTQGGLEEFYKEG
CCCCCCCCHHHHHHCC
>Mature Secondary Structure 
SVLVGRKAPEFDVAAVVNGSQFVDSCKLSDFKGKYVVLFFYPLDFTFVCPTELHAFQEK
CEECCCCCCCCCEEEEECCHHHHHHCCCCCCCCCEEEEEEECCCEEEECCHHHHHHHHH
IEEFKKRNVEVLGCSIDSKFSHFAWLRTPRSQGGIEGVTYTLLSDINKTVAADYDVLLED
HHHHHHCCEEEEEECCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
EGVALRGLFLIDRDGVVQHQVINNLSLGRNVDEVLRLIDALQFTEEFGEVCPANWNKGDK
CCCEEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AMKPTQGGLEEFYKEG
CCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]