Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 78188158

GI number: 78188158

Start: 195698

End: 196354

Strand: Reverse

Name: rpe [H]

Synonym: Cag_0175

Alternate gene names: 78188158

Gene position: 196354-195698 (Counterclockwise)

Preceding gene: 78188159

Following gene: 78188153

Centisome position: 7.63

GC content: 45.66

Gene sequence:

>657_bases
ATGCCAACAATTCTTGCCCCATCGGTATTATCAGCCGATTTTACCCGCCTTGCGGATTCCCTTACAATTGCTAATGAATC
GGGTGCTGAATGGATGCACTGCGATATTATGGATGGCAATTTTGTGCCAAACATCAGCTTTGGTCCATTTATTGTAAAAG
CGGTTGCATCATGCACCAGCATGATTATTGATACACATTTAATGATTACCGATCCCGATCGCTTTATTGAGGAGTTTGTA
AAAGCGGGTTCTCACCAAATTACCGTGCATCAAGAGGCGTGCCCTCACCTCCACCGTACTATTCAGCTTATTAAAAGCTT
TGGTGTAAAAGCGGGTGTTTCCATTAACCCTGGCACTCCCGTTTCAGCGCTTGAAGCCGTGTTAACGGATTTGGATTTAG
TGCTTTTGATGTCGGTAAATCCGGGATTTGGAGGGCAAAAATTTATTCCCTCAGCCGTAGGCAAAGTGCAGCAATTGCAT
GAAATGCGCATGAAGCTGAATCCTGAAATGGTGATTGCTGTTGATGGGGGAATTACGGAGGAAAATGCGCAGTCGGTAGT
GTCGGCAGGTGCAGATGCTCTGATTGCTGGAACGGCATTTTTTAAGGCTCCCGATCCAGCAAAAACAGCGGCTACAATTC
GTGCTATGTCCAGATAA

Upstream 100 bases:

>100_bases
TCTTAATGGAAGCGACTACACCTTTACGTTTGGTATTGGTGAAGCTTTTTAATTATTTCGCCACAACGGTTTTACCATTC
ACCCTTACAAAAAAAAGACT

Downstream 100 bases:

>100_bases
GCGAGCGAAGTTCGGTGCTGATATGAAGCCCTTCGCCTATCAGCACCGCATCAAATCCAGCCGCGTTGACAGCATCAATA
TCAGCCGCTCTTTTTAAGCC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPTILAPSVLSADFTRLADSLTIANESGAEWMHCDIMDGNFVPNISFGPFIVKAVASCTSMIIDTHLMITDPDRFIEEFV
KAGSHQITVHQEACPHLHRTIQLIKSFGVKAGVSINPGTPVSALEAVLTDLDLVLLMSVNPGFGGQKFIPSAVGKVQQLH
EMRMKLNPEMVIAVDGGITEENAQSVVSAGADALIAGTAFFKAPDPAKTAATIRAMSR

Sequences:

>Translated_218_residues
MPTILAPSVLSADFTRLADSLTIANESGAEWMHCDIMDGNFVPNISFGPFIVKAVASCTSMIIDTHLMITDPDRFIEEFV
KAGSHQITVHQEACPHLHRTIQLIKSFGVKAGVSINPGTPVSALEAVLTDLDLVLLMSVNPGFGGQKFIPSAVGKVQQLH
EMRMKLNPEMVIAVDGGITEENAQSVVSAGADALIAGTAFFKAPDPAKTAATIRAMSR
>Mature_217_residues
PTILAPSVLSADFTRLADSLTIANESGAEWMHCDIMDGNFVPNISFGPFIVKAVASCTSMIIDTHLMITDPDRFIEEFVK
AGSHQITVHQEACPHLHRTIQLIKSFGVKAGVSINPGTPVSALEAVLTDLDLVLLMSVNPGFGGQKFIPSAVGKVQQLHE
MRMKLNPEMVIAVDGGITEENAQSVVSAGADALIAGTAFFKAPDPAKTAATIRAMSR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=34.4339622641509, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=33.0188679245283, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI24307923, Length=167, Percent_Identity=30.5389221556886, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1789788, Length=216, Percent_Identity=43.5185185185185, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=35.2040816326531, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=33.6538461538462, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17552948, Length=215, Percent_Identity=39.0697674418605, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=216, Percent_Identity=40.2777777777778, Blast_Score=158, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=36.0189573459716, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23199; Mature: 23068

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTILAPSVLSADFTRLADSLTIANESGAEWMHCDIMDGNFVPNISFGPFIVKAVASCTS
CCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
MIIDTHLMITDPDRFIEEFVKAGSHQITVHQEACPHLHRTIQLIKSFGVKAGVSINPGTP
HHHHCEEEEECHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
VSALEAVLTDLDLVLLMSVNPGFGGQKFIPSAVGKVQQLHEMRMKLNPEMVIAVDGGITE
HHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
ENAQSVVSAGADALIAGTAFFKAPDPAKTAATIRAMSR
HHHHHHHHCCCCCEEECHHEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PTILAPSVLSADFTRLADSLTIANESGAEWMHCDIMDGNFVPNISFGPFIVKAVASCTS
CCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
MIIDTHLMITDPDRFIEEFVKAGSHQITVHQEACPHLHRTIQLIKSFGVKAGVSINPGTP
HHHHCEEEEECHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
VSALEAVLTDLDLVLLMSVNPGFGGQKFIPSAVGKVQQLHEMRMKLNPEMVIAVDGGITE
HHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
ENAQSVVSAGADALIAGTAFFKAPDPAKTAATIRAMSR
HHHHHHHHCCCCCEEECHHEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]