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The map label for this gene is plsC [H]

Identifier: 78188120

GI number: 78188120

Start: 150909

End: 151619

Strand: Reverse

Name: plsC [H]

Synonym: Cag_0137

Alternate gene names: 78188120

Gene position: 151619-150909 (Counterclockwise)

Preceding gene: 78188121

Following gene: 78188100

Centisome position: 5.89

GC content: 43.6

Gene sequence:

>711_bases
ATGAATTTCGGTACCATTTTATTTTTTCTTGTACTGATTCCTGTAATGTTTGCAGGAATGTCGCTATGGCTACTTATTAG
CTTTTTCGACAAACAAGGCGATATTTTTCACCGCATTGCTGCATGGTGGGGAGGCTTTAGCGCAAAGCTCTTTGGCATTA
AAATTGAGGTTATTGGGAGTGAAAATTACAATCCAGCACAACATTACTTGGTAGTCAGCAATCATGCGGGCATGGCTGAT
ATTCCGTTGCTGTTGGGTTGTATGAAGCTCAATTTGCGATTTCTTGCTAAGGAGGAACTTGGCAGAGTACCAATTTTTGG
TACAGCGTTGCGCCGCTCGGGCTACGTAATGATTAAGCGAGGGCAAAACCGTGAAGCCATGCAAAGCTTGCTTGCTGCGG
CTGAAGTGTTAAAAAGCGGGCGATCCGTCCACATTTTCCCTGAAGGTACTCGCTCAGCAACGGGCGAATTACTCCCTTTT
AAACGAGGCGCATTTTTAGTTGCCATAAAAGGTGGGGCTCCCGTTTTACCGGTTACCATTATTGGTAGCCACCTGATTAC
TCCAAAAAATAGCGTTAAAGTAAATCGTGGAACTATTCGCTTGATTATTGGCAAACCTATTGATCCTACCCAATTCAATA
GTGCTGAATCGCTAAAAAATGCTTGCGCAGAAGTGATTACAGAGGCGTTTCAGCGCTATAGGTTTAATTGA

Upstream 100 bases:

>100_bases
ATGGCAAAAGAAAAACGCTCCACCATTATTGGAGCGCACTATCAAGAGCTTGCTACTTTTTTAAAGCGATTAGATCGCTA
ACTCGTTAGCCAACAGCGCC

Downstream 100 bases:

>100_bases
GACGACAAATCTTAGGATTTTATAACTCATCAATATTCACTTCTATTGCATCTTTTTTCTCTTTTGCCCTTTCATTAATG
ATTTGAGCCAATTCAGAATC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNFGTILFFLVLIPVMFAGMSLWLLISFFDKQGDIFHRIAAWWGGFSAKLFGIKIEVIGSENYNPAQHYLVVSNHAGMAD
IPLLLGCMKLNLRFLAKEELGRVPIFGTALRRSGYVMIKRGQNREAMQSLLAAAEVLKSGRSVHIFPEGTRSATGELLPF
KRGAFLVAIKGGAPVLPVTIIGSHLITPKNSVKVNRGTIRLIIGKPIDPTQFNSAESLKNACAEVITEAFQRYRFN

Sequences:

>Translated_236_residues
MNFGTILFFLVLIPVMFAGMSLWLLISFFDKQGDIFHRIAAWWGGFSAKLFGIKIEVIGSENYNPAQHYLVVSNHAGMAD
IPLLLGCMKLNLRFLAKEELGRVPIFGTALRRSGYVMIKRGQNREAMQSLLAAAEVLKSGRSVHIFPEGTRSATGELLPF
KRGAFLVAIKGGAPVLPVTIIGSHLITPKNSVKVNRGTIRLIIGKPIDPTQFNSAESLKNACAEVITEAFQRYRFN
>Mature_236_residues
MNFGTILFFLVLIPVMFAGMSLWLLISFFDKQGDIFHRIAAWWGGFSAKLFGIKIEVIGSENYNPAQHYLVVSNHAGMAD
IPLLLGCMKLNLRFLAKEELGRVPIFGTALRRSGYVMIKRGQNREAMQSLLAAAEVLKSGRSVHIFPEGTRSATGELLPF
KRGAFLVAIKGGAPVLPVTIIGSHLITPKNSVKVNRGTIRLIIGKPIDPTQFNSAESLKNACAEVITEAFQRYRFN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=163, Percent_Identity=31.2883435582822, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI15100175, Length=163, Percent_Identity=31.2883435582822, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI6041665, Length=197, Percent_Identity=26.9035532994924, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1789395, Length=190, Percent_Identity=28.4210526315789, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17568319, Length=176, Percent_Identity=25.5681818181818, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17564032, Length=203, Percent_Identity=27.0935960591133, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=242, Percent_Identity=31.404958677686, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281364648, Length=224, Percent_Identity=25.4464285714286, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582856, Length=224, Percent_Identity=25.4464285714286, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582854, Length=224, Percent_Identity=25.4464285714286, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641614, Length=223, Percent_Identity=28.6995515695067, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641612, Length=223, Percent_Identity=28.6995515695067, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 26050; Mature: 26050

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFGTILFFLVLIPVMFAGMSLWLLISFFDKQGDIFHRIAAWWGGFSAKLFGIKIEVIGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEC
ENYNPAQHYLVVSNHAGMADIPLLLGCMKLNLRFLAKEELGRVPIFGTALRRSGYVMIKR
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEHHHCCCCCEEHHHHHCCCEEEEEE
GQNREAMQSLLAAAEVLKSGRSVHIFPEGTRSATGELLPFKRGAFLVAIKGGAPVLPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCEEEEEECCCCCEEEHEE
IGSHLITPKNSVKVNRGTIRLIIGKPIDPTQFNSAESLKNACAEVITEAFQRYRFN
ECCEEECCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFGTILFFLVLIPVMFAGMSLWLLISFFDKQGDIFHRIAAWWGGFSAKLFGIKIEVIGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEEEEEC
ENYNPAQHYLVVSNHAGMADIPLLLGCMKLNLRFLAKEELGRVPIFGTALRRSGYVMIKR
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEHHHCCCCCEEHHHHHCCCEEEEEE
GQNREAMQSLLAAAEVLKSGRSVHIFPEGTRSATGELLPFKRGAFLVAIKGGAPVLPVTI
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCEEEEEECCCCCEEEHEE
IGSHLITPKNSVKVNRGTIRLIIGKPIDPTQFNSAESLKNACAEVITEAFQRYRFN
ECCEEECCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]