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The map label for this gene is trpS [H]

Identifier: 78188056

GI number: 78188056

Start: 79762

End: 80826

Strand: Reverse

Name: trpS [H]

Synonym: Cag_0072

Alternate gene names: 78188056

Gene position: 80826-79762 (Counterclockwise)

Preceding gene: 78188059

Following gene: 78188055

Centisome position: 3.14

GC content: 48.83

Gene sequence:

>1065_bases
ATGGCAACAGCACGAATTTTAAGCGGCATGCGACCTACCGGCAAGCTCCATCTTGGACACTACACCGGTGCCCTTGAAAA
TTGGGTTGCCCAACAAAATCAATGCTCTGCGGATGGCAACCGCGCTTACGACACCTATTTTCTGATTGCCGATTACCATA
CCTTAACCACCTCGCTTTCAACCGATGACGTGTATGCTCATTCGCTTGATATGCTGGTGGATTGGCTTGCCGCTGGCATT
GATCCCGAAAAAAGTCCTATGTTTCGCCAATCGCAGGTAAAGCAACATGCCGAGCTTTTTTTGCTTTTCTCTATGCTTAT
TACCTCCGCACGCTTGGAGCGCAATCCAACGTTAAAAGAGCAAGTGCGCGACCTTCATATGGATTCAATGAGCTACGGGC
ATCTTGGCTATCCTGTTTTGCAATCAGCAGATATTTTGCTCTACAAGGCAAACGTGGTGCCTGTTGGTGAGGATCAAATT
CCCCATGTGGAAATTACCCGCGAAATTGCTCGCAAGTTTAACAACCACTTTCCTCATCCGCTTTACGGCAACGTCTTTGC
TGAACCTGAACCAAAAATCACCAAATTTGCACGCCTTGCAGGGCTTGACGGAAAAGCAAAAATGTCGAAATCACTCGGCA
ACACCATTTTCCTCTCCGATCCACCCGACGAAGTGCTCCGCAAAATGCGCACGGCGGTTACCGATACCCAAAAAGTGCGC
AAAAACGATGCAGGACGCCCCGAAGTGTGCACCGTTTTTAGTTACCACAAACGCTTTTCCACGCCTGAGCAGTGCGAAGA
AATTGCGGCTGGCTGCCAAAGCGGAGCGCTTGGTTGCGTTGATTGTAAAAAGCAGTGTGCCGCAAACATTTCTGCTGAAC
TTGCACCGCTCTTAGAACGCCGCACATACTACGAAGCTCGCATGGATGAGGTGAAAAATATTTTATTTGAGGGAGAAGCA
AAAGCGCGCACCGTTGCCGAACAGACCATGCAAGAGGTACGCACCGCAATGAAGCTTGGTGAAGCAAATTGCAGCGCCAC
TTTTTTCAACACTTCATGTTCATAG

Upstream 100 bases:

>100_bases
TATATATATAATGCTCAATCAGGCGAGATAGCGCACCCTAAGCGGAACGCACAATCTCTTGACGCCCATACAGCATTTCC
ATTTTAAAGCAAAAAAATCT

Downstream 100 bases:

>100_bases
CCATGCAACGCTCTGCTTTTATTTTTGATATGGATGGCGTTTTAACCGACAATATGCGCCTTCATGCCAATTCTTGGATT
GAACTATTTCGCGATTTTGG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MATARILSGMRPTGKLHLGHYTGALENWVAQQNQCSADGNRAYDTYFLIADYHTLTTSLSTDDVYAHSLDMLVDWLAAGI
DPEKSPMFRQSQVKQHAELFLLFSMLITSARLERNPTLKEQVRDLHMDSMSYGHLGYPVLQSADILLYKANVVPVGEDQI
PHVEITREIARKFNNHFPHPLYGNVFAEPEPKITKFARLAGLDGKAKMSKSLGNTIFLSDPPDEVLRKMRTAVTDTQKVR
KNDAGRPEVCTVFSYHKRFSTPEQCEEIAAGCQSGALGCVDCKKQCAANISAELAPLLERRTYYEARMDEVKNILFEGEA
KARTVAEQTMQEVRTAMKLGEANCSATFFNTSCS

Sequences:

>Translated_354_residues
MATARILSGMRPTGKLHLGHYTGALENWVAQQNQCSADGNRAYDTYFLIADYHTLTTSLSTDDVYAHSLDMLVDWLAAGI
DPEKSPMFRQSQVKQHAELFLLFSMLITSARLERNPTLKEQVRDLHMDSMSYGHLGYPVLQSADILLYKANVVPVGEDQI
PHVEITREIARKFNNHFPHPLYGNVFAEPEPKITKFARLAGLDGKAKMSKSLGNTIFLSDPPDEVLRKMRTAVTDTQKVR
KNDAGRPEVCTVFSYHKRFSTPEQCEEIAAGCQSGALGCVDCKKQCAANISAELAPLLERRTYYEARMDEVKNILFEGEA
KARTVAEQTMQEVRTAMKLGEANCSATFFNTSCS
>Mature_353_residues
ATARILSGMRPTGKLHLGHYTGALENWVAQQNQCSADGNRAYDTYFLIADYHTLTTSLSTDDVYAHSLDMLVDWLAAGID
PEKSPMFRQSQVKQHAELFLLFSMLITSARLERNPTLKEQVRDLHMDSMSYGHLGYPVLQSADILLYKANVVPVGEDQIP
HVEITREIARKFNNHFPHPLYGNVFAEPEPKITKFARLAGLDGKAKMSKSLGNTIFLSDPPDEVLRKMRTAVTDTQKVRK
NDAGRPEVCTVFSYHKRFSTPEQCEEIAAGCQSGALGCVDCKKQCAANISAELAPLLERRTYYEARMDEVKNILFEGEAK
ARTVAEQTMQEVRTAMKLGEANCSATFFNTSCS

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=336, Percent_Identity=36.0119047619048, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=41.1764705882353, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1789786, Length=350, Percent_Identity=35.7142857142857, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=30.4985337243402, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=362, Percent_Identity=30.6629834254144, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666151, Length=354, Percent_Identity=34.180790960452, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 39568; Mature: 39437

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATARILSGMRPTGKLHLGHYTGALENWVAQQNQCSADGNRAYDTYFLIADYHTLTTSLS
CCHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEHHHHHCCCC
TDDVYAHSLDMLVDWLAAGIDPEKSPMFRQSQVKQHAELFLLFSMLITSARLERNPTLKE
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QVRDLHMDSMSYGHLGYPVLQSADILLYKANVVPVGEDQIPHVEITREIARKFNNHFPHP
HHHHHHHCCCCCCCCCCHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHCCCCCC
LYGNVFAEPEPKITKFARLAGLDGKAKMSKSLGNTIFLSDPPDEVLRKMRTAVTDTQKVR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
KNDAGRPEVCTVFSYHKRFSTPEQCEEIAAGCQSGALGCVDCKKQCAANISAELAPLLER
HCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
RTYYEARMDEVKNILFEGEAKARTVAEQTMQEVRTAMKLGEANCSATFFNTSCS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
>Mature Secondary Structure 
ATARILSGMRPTGKLHLGHYTGALENWVAQQNQCSADGNRAYDTYFLIADYHTLTTSLS
CHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEHHHHHCCCC
TDDVYAHSLDMLVDWLAAGIDPEKSPMFRQSQVKQHAELFLLFSMLITSARLERNPTLKE
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
QVRDLHMDSMSYGHLGYPVLQSADILLYKANVVPVGEDQIPHVEITREIARKFNNHFPHP
HHHHHHHCCCCCCCCCCHHHCCCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHCCCCCC
LYGNVFAEPEPKITKFARLAGLDGKAKMSKSLGNTIFLSDPPDEVLRKMRTAVTDTQKVR
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHH
KNDAGRPEVCTVFSYHKRFSTPEQCEEIAAGCQSGALGCVDCKKQCAANISAELAPLLER
HCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
RTYYEARMDEVKNILFEGEAKARTVAEQTMQEVRTAMKLGEANCSATFFNTSCS
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]