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The map label for this gene is argS

Identifier: 78188054

GI number: 78188054

Start: 77346

End: 79004

Strand: Reverse

Name: argS

Synonym: Cag_0070

Alternate gene names: 78188054

Gene position: 79004-77346 (Counterclockwise)

Preceding gene: 78188055

Following gene: 78188045

Centisome position: 3.07

GC content: 44.3

Gene sequence:

>1659_bases
ATGATTGATTTTTTCCGCTCCGCTATAGCTGCTGCCCTTGCATCTGCCCAGCTCAATACCGCGAAACCTATTCAGCTTGA
ACAACCTGCTGATAAAAAGTTTGGTGACTTTTCAACCAACATTGCCATGCTGGCAGCAAAAGAGTGTGGCAAAAAGCCTC
GCGACTTAGCGCAAGAAATTATCAACCATCTCGCTTTTCCCCCCGATACAGTAGCAAAAATTGAGATTGCCGGTGCCGGC
TTTATCAATTTCTACCTTACCCCACGTTTTATTATGCGTTCGGTAGAACAGGTATTGCGTGATGGTGAAAAATTTGGGCA
ATCAACGGAAGGCAACGGAAAAAAAGCCATTGTTGAATATGTCAGCGCAAACCCAACAGGACCACTTACCATTGGGCGTG
GACGTGGTGGCGTAGTCGGCGACTGCATTGCAAACCTGCTGGCAACGCAAGGCTATGAGGTTACACGCGAATATTATTTC
AACGATGCAGGACGCCAAATGCAAATTCTCGGCGCATCGGTGCGCTTCCGTTACCTTGAACTATGCGGCAACACCATTGA
GTTCCCCGAAGATCACTATCAAGGCGACTACATTCGTGATATTGCAGCCACGCTGTACGAGCAACATGGCAATGCACTTG
AAAAGAGTGAAGAACTTGAACCTTTTAAAAAAGCTGCCGAAGAGCTGATTTTCAAATCAATAAAAGCCACACTCGAACGA
CTCAATATTCGCCACGATTCGTTCTTTAACGAACACAAACTTTATCTTGCAAATAATAATAGCCCATCTGCGAATACTGC
CGTTATACAATCTTTATCATCTTCTAATTTTATTGACGACTATGACGGAGCAACATGGTTTTTAACCACAAAGCTTGGTC
AAGAAAAAGACAAAGTTTTGATAAAATCAACAGGTGAACCAAGTTATCGCCTGCCCGATATAGCCTACCATGTAAACAAG
TTTCAGAGAGGTTTCGACCTAATGGTCAATGTGTTCGGTGCAGATCATATTGATGAATATCCTGACGTCCTTGAAGCCTT
GAAAATACTTGGCTACGACACAACAAAAGTTCACGTTGCCATTAACCAATTTGTAACCACTACGGTTAACGGACAAACCG
TAAAAATGTCAACCCGTAAAGGCAACGCTGATTTATTGGATGATCTTATTGCCGACGTTGGTGCTGATGCAACTCGCCTC
TTTTTTATTACTCGCAGCAAAGATTCACACCTTAATTTTGATGTTGAACTTGCAAAACGGCAATCAAAAGAAAATCCCGT
TTTTTACCTGCAATACGCCCATGCCCGCATTTGCAGCTTGCTCCGTTTAGCAAAGCAAGAAGTTGGATTTGATGCCGATA
CATATGGTTTTGCTGATGTCTTGCAAGTGTTAGATGGAGCGGCAGAAGTGCAACTTGGCTTTGCCTTACTGAACTTTCCA
GCCATGATTCAATCGAGTCTCCGCTTGCTTGAACCACAAAAAATGGTTGAATACCTTCACGCATTAGCCGAACACTTCCA
TCGCTTTTATCAAGAATCGCCCATCTTAAAAGCCGAGCCTGAGGTACGAACCGCACGCCTGCTGCTTTCGGTAGCAACAC
GCCAAGTGCTCCGCAACGGCTTTACCATTTTAGGGATTTCAGCACCCGAAGCGATGTAA

Upstream 100 bases:

>100_bases
TGCTACTGACCGAAAAACAAAACACCCTTGTTGCTTAACAAGCTAAGCAACAAGCACATTCAACAAACTACCCGCTAACG
AGAGATAAGCTTTTTTTGTT

Downstream 100 bases:

>100_bases
AAGAAAGGAGTAAAATGAGGGGTGGATACGGTAGGCACCTTAATGCACAAACAAAAACTCTTTCTACCGATACAACCCCT
CCTGCTCAATGTAGCGAAGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MIDFFRSAIAAALASAQLNTAKPIQLEQPADKKFGDFSTNIAMLAAKECGKKPRDLAQEIINHLAFPPDTVAKIEIAGAG
FINFYLTPRFIMRSVEQVLRDGEKFGQSTEGNGKKAIVEYVSANPTGPLTIGRGRGGVVGDCIANLLATQGYEVTREYYF
NDAGRQMQILGASVRFRYLELCGNTIEFPEDHYQGDYIRDIAATLYEQHGNALEKSEELEPFKKAAEELIFKSIKATLER
LNIRHDSFFNEHKLYLANNNSPSANTAVIQSLSSSNFIDDYDGATWFLTTKLGQEKDKVLIKSTGEPSYRLPDIAYHVNK
FQRGFDLMVNVFGADHIDEYPDVLEALKILGYDTTKVHVAINQFVTTTVNGQTVKMSTRKGNADLLDDLIADVGADATRL
FFITRSKDSHLNFDVELAKRQSKENPVFYLQYAHARICSLLRLAKQEVGFDADTYGFADVLQVLDGAAEVQLGFALLNFP
AMIQSSLRLLEPQKMVEYLHALAEHFHRFYQESPILKAEPEVRTARLLLSVATRQVLRNGFTILGISAPEAM

Sequences:

>Translated_552_residues
MIDFFRSAIAAALASAQLNTAKPIQLEQPADKKFGDFSTNIAMLAAKECGKKPRDLAQEIINHLAFPPDTVAKIEIAGAG
FINFYLTPRFIMRSVEQVLRDGEKFGQSTEGNGKKAIVEYVSANPTGPLTIGRGRGGVVGDCIANLLATQGYEVTREYYF
NDAGRQMQILGASVRFRYLELCGNTIEFPEDHYQGDYIRDIAATLYEQHGNALEKSEELEPFKKAAEELIFKSIKATLER
LNIRHDSFFNEHKLYLANNNSPSANTAVIQSLSSSNFIDDYDGATWFLTTKLGQEKDKVLIKSTGEPSYRLPDIAYHVNK
FQRGFDLMVNVFGADHIDEYPDVLEALKILGYDTTKVHVAINQFVTTTVNGQTVKMSTRKGNADLLDDLIADVGADATRL
FFITRSKDSHLNFDVELAKRQSKENPVFYLQYAHARICSLLRLAKQEVGFDADTYGFADVLQVLDGAAEVQLGFALLNFP
AMIQSSLRLLEPQKMVEYLHALAEHFHRFYQESPILKAEPEVRTARLLLSVATRQVLRNGFTILGISAPEAM
>Mature_552_residues
MIDFFRSAIAAALASAQLNTAKPIQLEQPADKKFGDFSTNIAMLAAKECGKKPRDLAQEIINHLAFPPDTVAKIEIAGAG
FINFYLTPRFIMRSVEQVLRDGEKFGQSTEGNGKKAIVEYVSANPTGPLTIGRGRGGVVGDCIANLLATQGYEVTREYYF
NDAGRQMQILGASVRFRYLELCGNTIEFPEDHYQGDYIRDIAATLYEQHGNALEKSEELEPFKKAAEELIFKSIKATLER
LNIRHDSFFNEHKLYLANNNSPSANTAVIQSLSSSNFIDDYDGATWFLTTKLGQEKDKVLIKSTGEPSYRLPDIAYHVNK
FQRGFDLMVNVFGADHIDEYPDVLEALKILGYDTTKVHVAINQFVTTTVNGQTVKMSTRKGNADLLDDLIADVGADATRL
FFITRSKDSHLNFDVELAKRQSKENPVFYLQYAHARICSLLRLAKQEVGFDADTYGFADVLQVLDGAAEVQLGFALLNFP
AMIQSSLRLLEPQKMVEYLHALAEHFHRFYQESPILKAEPEVRTARLLLSVATRQVLRNGFTILGISAPEAM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=613, Percent_Identity=24.7960848287113, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1788184, Length=604, Percent_Identity=26.8211920529801, Blast_Score=133, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=234, Percent_Identity=28.6324786324786, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71985068, Length=234, Percent_Identity=28.6324786324786, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320548, Length=610, Percent_Identity=25.9016393442623, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321883, Length=524, Percent_Identity=25.1908396946565, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18859963, Length=624, Percent_Identity=25, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CHLCH (Q3ANY2)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378392.1
- ProteinModelPortal:   Q3ANY2
- STRING:   Q3ANY2
- GeneID:   3746404
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0070
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   CCHL340177:CAG_0070-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61626; Mature: 61626

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFFRSAIAAALASAQLNTAKPIQLEQPADKKFGDFSTNIAMLAAKECGKKPRDLAQEI
CHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
INHLAFPPDTVAKIEIAGAGFINFYLTPRFIMRSVEQVLRDGEKFGQSTEGNGKKAIVEY
HHHCCCCCCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VSANPTGPLTIGRGRGGVVGDCIANLLATQGYEVTREYYFNDAGRQMQILGASVRFRYLE
HCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
LCGNTIEFPEDHYQGDYIRDIAATLYEQHGNALEKSEELEPFKKAAEELIFKSIKATLER
HCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LNIRHDSFFNEHKLYLANNNSPSANTAVIQSLSSSNFIDDYDGATWFLTTKLGQEKDKVL
HCCHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEE
IKSTGEPSYRLPDIAYHVNKFQRGFDLMVNVFGADHIDEYPDVLEALKILGYDTTKVHVA
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEE
INQFVTTTVNGQTVKMSTRKGNADLLDDLIADVGADATRLFFITRSKDSHLNFDVELAKR
EEHHEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHH
QSKENPVFYLQYAHARICSLLRLAKQEVGFDADTYGFADVLQVLDGAAEVQLGFALLNFP
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
AMIQSSLRLLEPQKMVEYLHALAEHFHRFYQESPILKAEPEVRTARLLLSVATRQVLRNG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FTILGISAPEAM
CEEEEECCCCCC
>Mature Secondary Structure
MIDFFRSAIAAALASAQLNTAKPIQLEQPADKKFGDFSTNIAMLAAKECGKKPRDLAQEI
CHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
INHLAFPPDTVAKIEIAGAGFINFYLTPRFIMRSVEQVLRDGEKFGQSTEGNGKKAIVEY
HHHCCCCCCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VSANPTGPLTIGRGRGGVVGDCIANLLATQGYEVTREYYFNDAGRQMQILGASVRFRYLE
HCCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHH
LCGNTIEFPEDHYQGDYIRDIAATLYEQHGNALEKSEELEPFKKAAEELIFKSIKATLER
HCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LNIRHDSFFNEHKLYLANNNSPSANTAVIQSLSSSNFIDDYDGATWFLTTKLGQEKDKVL
HCCHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEE
IKSTGEPSYRLPDIAYHVNKFQRGFDLMVNVFGADHIDEYPDVLEALKILGYDTTKVHVA
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEE
INQFVTTTVNGQTVKMSTRKGNADLLDDLIADVGADATRLFFITRSKDSHLNFDVELAKR
EEHHEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHH
QSKENPVFYLQYAHARICSLLRLAKQEVGFDADTYGFADVLQVLDGAAEVQLGFALLNFP
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
AMIQSSLRLLEPQKMVEYLHALAEHFHRFYQESPILKAEPEVRTARLLLSVATRQVLRNG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FTILGISAPEAM
CEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA