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The map label for this gene is yafC [C]

Identifier: 78067951

GI number: 78067951

Start: 3651598

End: 3652647

Strand: Reverse

Name: yafC [C]

Synonym: Bcep18194_A6482

Alternate gene names: 78067951

Gene position: 3652647-3651598 (Counterclockwise)

Preceding gene: 78067953

Following gene: 78067947

Centisome position: 98.88

GC content: 66.29

Gene sequence:

>1050_bases
ATGGATCATTTGCAGTCGATGCGCGTGTTCGTCAAGGTTGCAGATCTCGGCAGTTTTGCGCGGGCCGCGAGTGCAATGGA
TATCTCCAACGCGGTCGCGACGCGTCACGTCGCCGATCTGGAAGGCCGGCTCGGCACGCGTTTGCTGAACCGCACCACGC
GCAGCCTTTCCCTGACGGAGTCAGGCCAGGTCTATCTGGAGCGTGCTCGCCAGATCCTCGATGAGCTCGAGGACGTCGAG
CAGATGGTCGTTGCGCGCAATCACGAGCCGGTCGGAACGTTGCGCATCGTTGCGCCGGTCGTGTTCGGCCTGCATAACCT
CGCGCCCGTGTTGCAGTCGTACACGGAGAATTTCCCGAAAGTGGTGCCCGATCTCACGCTGGTCGACCGGCAGGTCGATC
TCGTCGAGGAAGGCTTCGACGTCGGCATCGTCGTCACGCGCCAGATGCGTAGCGCGAGCATCGTCACGCGGCGCCTGACC
ACCGGCTGCATGACCGTGTGCGCGACGCCGAGCTACCTGGAGAAGCACGGTGTGCCGACCCATCCGGAGCATCTCGCCGA
GCACCCGAGCCTGAGCCTGCCGACCGAATACTGGGGCGACGAGCGCGTGTTCACGGGGCCGGACGGTGAAGTGCGCGTGC
GCCCGACCAACGTGATCGTCGCGAACAACACCGCGATGCTGCGCCAGTTCGCGCTGCTCGGGATGGGGGTCGCGATCCTG
CCGAGCTACCTGATCGGCAGCGACATCGCGCGCGGCGCGCTCGTGCGGCTGCTGCCGGATTTCCGGCTGCCGCAGGTCGA
GATCAACATCGCTTACCCGAGCCGGCGCCATTTGCCTGCGAAGGTGCGCACGTTCATCGACCACCTCGTCGAGCATTTCA
GTCACTCGACCGATGCGACGATGGGCGAGCAGTGGGCCGCGCAGAATTCGGCGCTTCCGCCGATCGGTGTCGAGACGCGT
GCGGAGCAGCCGGAATCGGCCGACCCGAACCTGTCGCCGCGCCTGCCGCGTTCGCCGCGCCCGCGCGTCGCGGTGCCGTC
GCCACTGTAA

Upstream 100 bases:

>100_bases
CAAGGGCCTTGTTGAGCAACTCTGCATCATTTCCGCTGTCGTAGGAGAATTACGCATTTGCTTCATCTTTTTGAAGTTGT
AACAGCGGCAGGAGTCGTTT

Downstream 100 bases:

>100_bases
CGGCGCGACGGCCGGGCGGCGGTTGCCGCCGGCACAAAGAAAAACGCGGATCGAGCAATCGATCCGCGTTTTTTTATCGC
TGCCTGCCGGAATCCGGCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTENFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEHLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGSDIARGALVRLLPDFRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSHSTDATMGEQWAAQNSALPPIGVETR
AEQPESADPNLSPRLPRSPRPRVAVPSPL

Sequences:

>Translated_349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTENFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEHLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGSDIARGALVRLLPDFRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSHSTDATMGEQWAAQNSALPPIGVETR
AEQPESADPNLSPRLPRSPRPRVAVPSPL
>Mature_349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTENFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEHLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGSDIARGALVRLLPDFRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSHSTDATMGEQWAAQNSALPPIGVETR
AEQPESADPNLSPRLPRSPRPRVAVPSPL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=33.5640138408304, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.9931972789116, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=31.3531353135314, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.3515358361775, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=28.476821192053, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789440, Length=259, Percent_Identity=28.957528957529, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=28.9655172413793, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790011, Length=307, Percent_Identity=23.4527687296417, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=26.2357414448669, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=23.1833910034602, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=143, Percent_Identity=29.3706293706294, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38524; Mature: 38524

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTENFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLTTGCMTVCATPSYLEKHGVPT
HCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPEHLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
CHHHHHCCCCCCCCHHHCCCCEEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGSDIARGALVRLLPDFRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSHSTDAT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCH
MGEQWAAQNSALPPIGVETRAEQPESADPNLSPRLPRSPRPRVAVPSPL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTENFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLTTGCMTVCATPSYLEKHGVPT
HCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPEHLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
CHHHHHCCCCCCCCHHHCCCCEEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGSDIARGALVRLLPDFRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSHSTDAT
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCH
MGEQWAAQNSALPPIGVETRAEQPESADPNLSPRLPRSPRPRVAVPSPL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]