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The map label for this gene is garL [H]

Identifier: 78067936

GI number: 78067936

Start: 3634667

End: 3635452

Strand: Reverse

Name: garL [H]

Synonym: Bcep18194_A6467

Alternate gene names: 78067936

Gene position: 3635452-3634667 (Counterclockwise)

Preceding gene: 78067937

Following gene: 78067935

Centisome position: 98.41

GC content: 70.87

Gene sequence:

>786_bases
ATGAGCACGCTCACCAATTCCCTCAAACAACGCCTGCGCGACGGCGACGAGCCGCTGTACGGCCTGTGGCTGTCGCTCGG
CAGCGAGTCGGCCGCGGAAGCGCTCGCGCATGCCGGCTACGACTGGCTCTGCATCGACATGGAGCACGCGCCGAACGACA
GCCGCGATGTTGCATCGCAGTTGCGCGCGATCGCCGCCGCCCATCTGCCGAGTGAGCCCGTCGTGCGCGTGCCGGCGCGC
GAGCCGTGGCTCGTGAAGCGCGCGCTCGATGCAGGCGCACGCACGCTGATGTTTCCCGGTATCGAGACACCGGACGATGC
CGTGCATGCGGTGCGGCTCACGCGTTATCCGTCGCCCGATTCGCCGGACGGGCTGCGCGGCGTCGCGGGCATGGTGCGCG
CGGCGGCGTTCGGCATGCGCCGCGATTACGTGCAGACGGCGAATGCGCAGGTCGCGGTGATCGTGCAGATCGAATCGGCG
CGCGGCGTCGACGAAGTCGAGCGGATTGCGGCGCTGCCCGGCGTCGACTGCCTGTTCGTCGGCCCGGCCGATCTCGCGGC
GAGCCTCGGGCATCTCGGCGACATCCGCCACCCGGATGTCGAAACCGCGATGGCGCGCGTGCTCGCGGCCGGCCGGCAGG
CCGGTGTCGCGGTCGGCATCTTCGCGGGCGATACGGCGGCCGCGCGCCAGTATCGCGAGGCCGGCTACCGGATGATCACG
CTGTCGGCCGACGTCAGCTGGCTGTTGCGTGCCACGCGGCAGGCGCTGCAGGAGGTACGGTCATGA

Upstream 100 bases:

>100_bases
CGGTCCTGGCGCCGCCGTGCATCGCTGCCCGGCGTGTCGCGCTCCGCTTTGCCCGTTGCTTGTCCCGTTCGATTGCCGTT
CCGTCCAGGAGGCCGTATCG

Downstream 100 bases:

>100_bases
ACGGTGGCGATGGCGCGTGCCGTGGGCGCGCGCGGGGTGTGACCGGGCGGCGCGGGCAGGTCGGCGCGATGCTCGGCCTG
TGGGTCGTGTGGATCGCGGC

Product: 2-dehydro-3-deoxyglucarate aldolase

Products: NA

Alternate protein names: KDGluc aldolase; KDGlucA; 2-dehydro-3-deoxy-D-glucarate aldolase; 2-keto-3-deoxy-D-glucarate aldolase; 5-dehydro-4-deoxy-D-glucarate aldolase; Alpha-keto-beta-deoxy-D-glucarate aldolase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSTLTNSLKQRLRDGDEPLYGLWLSLGSESAAEALAHAGYDWLCIDMEHAPNDSRDVASQLRAIAAAHLPSEPVVRVPAR
EPWLVKRALDAGARTLMFPGIETPDDAVHAVRLTRYPSPDSPDGLRGVAGMVRAAAFGMRRDYVQTANAQVAVIVQIESA
RGVDEVERIAALPGVDCLFVGPADLAASLGHLGDIRHPDVETAMARVLAAGRQAGVAVGIFAGDTAAARQYREAGYRMIT
LSADVSWLLRATRQALQEVRS

Sequences:

>Translated_261_residues
MSTLTNSLKQRLRDGDEPLYGLWLSLGSESAAEALAHAGYDWLCIDMEHAPNDSRDVASQLRAIAAAHLPSEPVVRVPAR
EPWLVKRALDAGARTLMFPGIETPDDAVHAVRLTRYPSPDSPDGLRGVAGMVRAAAFGMRRDYVQTANAQVAVIVQIESA
RGVDEVERIAALPGVDCLFVGPADLAASLGHLGDIRHPDVETAMARVLAAGRQAGVAVGIFAGDTAAARQYREAGYRMIT
LSADVSWLLRATRQALQEVRS
>Mature_260_residues
STLTNSLKQRLRDGDEPLYGLWLSLGSESAAEALAHAGYDWLCIDMEHAPNDSRDVASQLRAIAAAHLPSEPVVRVPARE
PWLVKRALDAGARTLMFPGIETPDDAVHAVRLTRYPSPDSPDGLRGVAGMVRAAAFGMRRDYVQTANAQVAVIVQIESAR
GVDEVERIAALPGVDCLFVGPADLAASLGHLGDIRHPDVETAMARVLAAGRQAGVAVGIFAGDTAAARQYREAGYRMITL
SADVSWLLRATRQALQEVRS

Specific function: Catalyzes the reversible retro-aldol cleavage of both 5- keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789514, Length=234, Percent_Identity=43.5897435897436, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1788578, Length=218, Percent_Identity=43.5779816513761, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR017648
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.2.20 [H]

Molecular weight: Translated: 27986; Mature: 27855

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLTNSLKQRLRDGDEPLYGLWLSLGSESAAEALAHAGYDWLCIDMEHAPNDSRDVASQ
CCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
LRAIAAAHLPSEPVVRVPAREPWLVKRALDAGARTLMFPGIETPDDAVHAVRLTRYPSPD
HHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHEECCCCCC
SPDGLRGVAGMVRAAAFGMRRDYVQTANAQVAVIVQIESARGVDEVERIAALPGVDCLFV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEE
GPADLAASLGHLGDIRHPDVETAMARVLAAGRQAGVAVGIFAGDTAAARQYREAGYRMIT
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCEEEE
LSADVSWLLRATRQALQEVRS
EECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STLTNSLKQRLRDGDEPLYGLWLSLGSESAAEALAHAGYDWLCIDMEHAPNDSRDVASQ
CHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHH
LRAIAAAHLPSEPVVRVPAREPWLVKRALDAGARTLMFPGIETPDDAVHAVRLTRYPSPD
HHHHHHHCCCCCCEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHEECCCCCC
SPDGLRGVAGMVRAAAFGMRRDYVQTANAQVAVIVQIESARGVDEVERIAALPGVDCLFV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEE
GPADLAASLGHLGDIRHPDVETAMARVLAAGRQAGVAVGIFAGDTAAARQYREAGYRMIT
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCEEEE
LSADVSWLLRATRQALQEVRS
EECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA