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The map label for this gene is yhdG [H]

Identifier: 78067873

GI number: 78067873

Start: 3572322

End: 3573728

Strand: Direct

Name: yhdG [H]

Synonym: Bcep18194_A6404

Alternate gene names: 78067873

Gene position: 3572322-3573728 (Clockwise)

Preceding gene: 78067872

Following gene: 78067874

Centisome position: 96.7

GC content: 67.45

Gene sequence:

>1407_bases
ATGTCTCTCTTCCGCAAGAAAAACGTCGATCGCATGATCGCCGGCGCGCATGCCGCCGGGCTCAAGAAAGCGCTCGGCGC
GATCGACCTCACCTTCCTCGGCATCGGCGCAATCATCGGCACCGGCATCTTCGTGCTGACCGGGACCGGCGCCGTGCAGG
CCGGCCCTGCACTGATGCTGTCGTTCGTGATCGCCGCGATCGCGTGCGGCCTCGCCGCGCTGTCGTACGCGGAGTTCGCG
TCGACGATCCCCGTCGCCGGCTCGATCTACACGTATTCGTACGCCACCCTCGGCGAGCTCGTCGCGTGGATCATCGGCTG
GGACCTGATGCTCGAATACGGCCTCGCGTCGTCGGCCGTGTCGGTCGGCTGGTCGGGCTACCTGCAGTCCCTGCTGCAGG
GCTTCGGGCTGACGCTGCCCACCGTGCTGACGGCCGCGCCCGGCGCGGTGCCGGGTGTCGTCACGTGGTTCAACCTGCCC
GCGTTCCTCGTGATGATCGTGATCACGACGCTGCTGTCGATCGGCATCCGCGAGTCGACCCGCATCAACAACATCATGGT
GTTCATCAAGGTGTCGGTCGTGCTGCTCGTGATCGCGGTCGGCGTGTTCCACGTGACGCCCGCGAACTGGAAGCCGTTCA
TGCCGCACGGCTGGAACGGCGTGTTCGGCGCGGCGGCCGTGATGTTCTTCGCGTTCATCGGCTTCGACGCAGTGTCGTCG
GCGGCCGAGGAAGTGAAGAATCCGAAGCGCGACCTGCCGATCGGCATCATCGCGTCGCTCGCGGTGTGCGCGGTGCTGTA
CGTGACGGTCGCCGCGGTCGCGACCGGCATCGTGCCGTCGGCCCAGTACGCGAACATCTCGCACCCGATCTCGTACGCGC
TGCAGAAGGCCGGCGAGACGTGGGTCGCCGGCTTCATCGATCTCGGCGCGGTGCTCGGCATGCTGACCGTGATCCTCGTG
ATGAGCTACGGCCAGACGCGCGTGATCTTCGCGATGTCGCGCGACGGGCTGCTGCCGGCGGCGCTGTCGCGCGTGCACCC
GCGCTACGCGACGCCGTTCCTGACGACCTGGCTCGTCGGCCTGTTCTTCGGGCTGATCGCCGCGCTCGTGCCGCTCAACG
TGCTCGCCGAGCTGATCAACATCGGCACGCTCGCCGCGTTCTCGATGGTGTCGATCGCGGTGCTCGTGCTGCGTCGCACG
CACCCCGACCTGCCGCGTGCGTTCCGCTGCCCCGGCGTGCCCGTGGTGCCGATCCTCGCGGTCGCGTCGTGCCTGTTCCT
GATGCTGAACCTGCAGCCCATCACGTGGGCCGCGTTCGGCATCTGGCTCGTGATCGGCCTCGTGATCTACTTCCTGTACT
CGCGTCACCACTCGAAGCTCGCGCACGGTCACCACGACGCGCACTGA

Upstream 100 bases:

>100_bases
CGCTGCGCTGCAGCGGGTCTTGTGCGCCAAATCGGCTAAAATTACGGGTTTTCACTCAGTCAGCGCTACCGCGCCTGCGC
GCGCTGGCGATTCATCCGCA

Downstream 100 bases:

>100_bases
GCGCCGCCGTGCCGCACGCGGCACGGTGCGCACCCGCGGGGCCGGATACCGGCCCCGCACCCTCCCTGCCTTCACCCGCC
CCGCCGCCACGTTGCTTTTC

Product: amino acid tranporter

Products: L-tryptophan [Cytoplasm]; Proton [Cytoplasm]; Proton [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLP
AFLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQKAGETWVAGFIDLGAVLGMLTVILV
MSYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPVVPILAVASCLFLMLNLQPITWAAFGIWLVIGLVIYFLYSRHHSKLAHGHHDAH

Sequences:

>Translated_468_residues
MSLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFA
STIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLP
AFLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSS
AAEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQKAGETWVAGFIDLGAVLGMLTVILV
MSYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRT
HPDLPRAFRCPGVPVVPILAVASCLFLMLNLQPITWAAFGIWLVIGLVIYFLYSRHHSKLAHGHHDAH
>Mature_467_residues
SLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALMLSFVIAAIACGLAALSYAEFAS
TIPVAGSIYTYSYATLGELVAWIIGWDLMLEYGLASSAVSVGWSGYLQSLLQGFGLTLPTVLTAAPGAVPGVVTWFNLPA
FLVMIVITTLLSIGIRESTRINNIMVFIKVSVVLLVIAVGVFHVTPANWKPFMPHGWNGVFGAAAVMFFAFIGFDAVSSA
AEEVKNPKRDLPIGIIASLAVCAVLYVTVAAVATGIVPSAQYANISHPISYALQKAGETWVAGFIDLGAVLGMLTVILVM
SYGQTRVIFAMSRDGLLPAALSRVHPRYATPFLTTWLVGLFFGLIAALVPLNVLAELINIGTLAAFSMVSIAVLVLRRTH
PDLPRAFRCPGVPVVPILAVASCLFLMLNLQPITWAAFGIWLVIGLVIYFLYSRHHSKLAHGHHDAH

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of The Aromatic Amino Acids (Phenylalanine, Tyrosine, And Tryptophan). [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=35.3211009174312, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI258614003, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI258614005, Length=426, Percent_Identity=33.5680751173709, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI181337167, Length=409, Percent_Identity=34.718826405868, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=34.037558685446, Blast_Score=215, Evalue=7e-56,
Organism=Homo sapiens, GI110347453, Length=385, Percent_Identity=35.3246753246753, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI114326544, Length=438, Percent_Identity=32.648401826484, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI114326550, Length=438, Percent_Identity=32.648401826484, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI187423910, Length=488, Percent_Identity=26.0245901639344, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7657591, Length=488, Percent_Identity=26.0245901639344, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=26.3922518159806, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=26.3922518159806, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=26.3922518159806, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33286428, Length=482, Percent_Identity=25.3112033195021, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115648063, Length=413, Percent_Identity=24.2130750605327, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI115648022, Length=413, Percent_Identity=24.2130750605327, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI7657683, Length=402, Percent_Identity=25.1243781094527, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI71979932, Length=419, Percent_Identity=25.7756563245823, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI9790235, Length=299, Percent_Identity=23.4113712374582, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786302, Length=478, Percent_Identity=23.8493723849372, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082023, Length=450, Percent_Identity=23.7777777777778, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081915, Length=432, Percent_Identity=24.3055555555556, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786602, Length=476, Percent_Identity=23.5294117647059, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788480, Length=503, Percent_Identity=26.441351888668, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786789, Length=352, Percent_Identity=22.7272727272727, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081708, Length=486, Percent_Identity=22.8395061728395, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081869, Length=391, Percent_Identity=22.7621483375959, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082250, Length=426, Percent_Identity=24.4131455399061, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786694, Length=400, Percent_Identity=25.25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994972, Length=351, Percent_Identity=23.6467236467236, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI2367353, Length=363, Percent_Identity=26.9972451790634, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786908, Length=328, Percent_Identity=22.5609756097561, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=412, Percent_Identity=36.1650485436893, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17533459, Length=410, Percent_Identity=35.1219512195122, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17531343, Length=406, Percent_Identity=34.7290640394089, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17540018, Length=434, Percent_Identity=25.5760368663594, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=24.1217798594848, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=424, Percent_Identity=27.122641509434, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32566695, Length=424, Percent_Identity=27.122641509434, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=383, Percent_Identity=25.3263707571802, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=441, Percent_Identity=22.4489795918367, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=441, Percent_Identity=22.4489795918367, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.668449197861, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319991, Length=354, Percent_Identity=26.8361581920904, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=38.3132530120482, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=38.3132530120482, Blast_Score=272, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24667468, Length=403, Percent_Identity=35.7320099255583, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=33.5664335664336, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=33.5664335664336, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=33.5664335664336, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI281366235, Length=427, Percent_Identity=34.4262295081967, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI116007820, Length=427, Percent_Identity=34.4262295081967, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=35.1415094339623, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=34.6246973365617, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=34.6246973365617, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21357367, Length=454, Percent_Identity=27.0925110132159, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221331183, Length=448, Percent_Identity=24.3303571428571, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17647653, Length=448, Percent_Identity=24.3303571428571, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24664379, Length=448, Percent_Identity=24.3303571428571, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24651635, Length=419, Percent_Identity=24.582338902148, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651633, Length=419, Percent_Identity=24.582338902148, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641993, Length=422, Percent_Identity=26.7772511848341, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641995, Length=422, Percent_Identity=26.7772511848341, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550968, Length=472, Percent_Identity=22.8813559322034, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921172, Length=472, Percent_Identity=22.8813559322034, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49574; Mature: 49442

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLFRKKNVDRMIAGAHAAGLKKALGAIDLTFLGIGAIIGTGIFVLTGTGAVQAGPALML
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHCCHHHHH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HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-tryptophan [Periplasm]; Proton [Periplasm]; Proton [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: L-tryptophan [Periplasm] + Proton [Periplasm] = L-tryptophan [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] +

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]