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The map label for this gene is degS [H]

Identifier: 78067871

GI number: 78067871

Start: 3570622

End: 3571437

Strand: Direct

Name: degS [H]

Synonym: Bcep18194_A6402

Alternate gene names: 78067871

Gene position: 3570622-3571437 (Clockwise)

Preceding gene: 78067870

Following gene: 78067872

Centisome position: 96.66

GC content: 72.3

Gene sequence:

>816_bases
ATGGATACGTCGCTTAGCGCGCCTTTGGGCGCCCACGCCCCGTTCCCGTCGCAACAGCTCGTGCCGGGCTGCGTCGCGAC
TCCGCCCATTGCCGACGCCGCGTCGAAACGCGGTGCCTCCGCCGCGCGGATCGCAGCGCTGTCTGCCCAGTTGCTCGCCG
CCGACGAAGCGGCCCGCCGCCACCTGGCAGGCGAGCTGCACGACGGACTCGGTGCCGAACTGACCGCTGCTCGTTTCGCG
CTCGCAAACGTTCAAACGTGGCTACCGGCCGATGCGCCGGAGGGTTGCCTGCGCGCGCTGGCGCTTGCGCAGCAGGCACT
CGACTCCGCGACCGACGCGAATCGCCGGCTGATCGACGAACGCGACACGCCGGCGCTCGACGCGGGCCTGGTCGGCGCGC
TGTCGTCGTGGGCCGACACCCATGCGGCACGCACCGGCCTGCGCACAAGCTTCGTCTGTGCGGCCGACGCACGCCTGACG
CAGATCGCCGGCGCCAGCGCGCTCGCGGTGTTCCGCGTCGCGCAGGAAGCGTTGTCGAACGTCGCGAAGCATGCCCGCGC
GACGTCGGTCGACGTGCGGATCGCCACCGACGGCACGCACCTGTCACTGATTGTCTCCGACGATGGGACCGGTTTCTCCC
GAAGCCGTCGCACCGGCTACGGTCTCGCCGGCATGCGCGCCCGCTGCGAGGCGTTCGCCGGCAGCTTCGAGACGGCCACG
CCGGACGCCGGCCACGGCACGCGCGTCACCGCCCGCTTCGCTTGGGATTCGCTGCTCGCGGTGCCCGTCGCGGCCCGCCG
CGCGTCGCTTTCGTGA

Upstream 100 bases:

>100_bases
TCGGCAGGGGGCGATTCTCTGGCGGCGACCGTCATCAAAACGGCCGCCGTTCCACGCAGCCAGCCGGTGTCTGAACCGCT
TTCTGACAGCAGGGAGAGTC

Downstream 100 bases:

>100_bases
GGTCGTCATGAGCCTGAACATCCTGCTCGTGGACGATCACGCGATCGTCCGGCAAGGGATCCGCCAGTTGCTGATCGACC
GTGGCGTCGCACGCGACGTC

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MDTSLSAPLGAHAPFPSQQLVPGCVATPPIADAASKRGASAARIAALSAQLLAADEAARRHLAGELHDGLGAELTAARFA
LANVQTWLPADAPEGCLRALALAQQALDSATDANRRLIDERDTPALDAGLVGALSSWADTHAARTGLRTSFVCAADARLT
QIAGASALAVFRVAQEALSNVAKHARATSVDVRIATDGTHLSLIVSDDGTGFSRSRRTGYGLAGMRARCEAFAGSFETAT
PDAGHGTRVTARFAWDSLLAVPVAARRASLS

Sequences:

>Translated_271_residues
MDTSLSAPLGAHAPFPSQQLVPGCVATPPIADAASKRGASAARIAALSAQLLAADEAARRHLAGELHDGLGAELTAARFA
LANVQTWLPADAPEGCLRALALAQQALDSATDANRRLIDERDTPALDAGLVGALSSWADTHAARTGLRTSFVCAADARLT
QIAGASALAVFRVAQEALSNVAKHARATSVDVRIATDGTHLSLIVSDDGTGFSRSRRTGYGLAGMRARCEAFAGSFETAT
PDAGHGTRVTARFAWDSLLAVPVAARRASLS
>Mature_271_residues
MDTSLSAPLGAHAPFPSQQLVPGCVATPPIADAASKRGASAARIAALSAQLLAADEAARRHLAGELHDGLGAELTAARFA
LANVQTWLPADAPEGCLRALALAQQALDSATDANRRLIDERDTPALDAGLVGALSSWADTHAARTGLRTSFVCAADARLT
QIAGASALAVFRVAQEALSNVAKHARATSVDVRIATDGTHLSLIVSDDGTGFSRSRRTGYGLAGMRARCEAFAGSFETAT
PDAGHGTRVTARFAWDSLLAVPVAARRASLS

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082311, Length=226, Percent_Identity=28.3185840707965, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788812, Length=237, Percent_Identity=28.6919831223629, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27856; Mature: 27856

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSLSAPLGAHAPFPSQQLVPGCVATPPIADAASKRGASAARIAALSAQLLAADEAARR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HLAGELHDGLGAELTAARFALANVQTWLPADAPEGCLRALALAQQALDSATDANRRLIDE
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCC
RDTPALDAGLVGALSSWADTHAARTGLRTSFVCAADARLTQIAGASALAVFRVAQEALSN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHH
VAKHARATSVDVRIATDGTHLSLIVSDDGTGFSRSRRTGYGLAGMRARCEAFAGSFETAT
HHHHHHHCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
PDAGHGTRVTARFAWDSLLAVPVAARRASLS
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTSLSAPLGAHAPFPSQQLVPGCVATPPIADAASKRGASAARIAALSAQLLAADEAARR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HLAGELHDGLGAELTAARFALANVQTWLPADAPEGCLRALALAQQALDSATDANRRLIDE
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCC
RDTPALDAGLVGALSSWADTHAARTGLRTSFVCAADARLTQIAGASALAVFRVAQEALSN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHH
VAKHARATSVDVRIATDGTHLSLIVSDDGTGFSRSRRTGYGLAGMRARCEAFAGSFETAT
HHHHHHHCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
PDAGHGTRVTARFAWDSLLAVPVAARRASLS
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]