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The map label for this gene is 78067844

Identifier: 78067844

GI number: 78067844

Start: 3540431

End: 3541795

Strand: Direct

Name: 78067844

Synonym: Bcep18194_A6375

Alternate gene names: NA

Gene position: 3540431-3541795 (Clockwise)

Preceding gene: 78067843

Following gene: 78067846

Centisome position: 95.84

GC content: 70.33

Gene sequence:

>1365_bases
ATGCCATATTTCCGCATTCCGTTTTCACACCGCGTCGCCGCCGTGTCCGCCGTCGCGGCGCTGGGCACCGCCTTGACGCT
CCCCGTCGCACAGGCCGCCGGCCCCGCGCCGCTGCCCACGCCGACGGGCGACATGTCGCTGTCGCCGGCCGGCCCCGACA
TCGTGCCGCCGGCCGCCTCGAGCGCGCCGGGCACGCCGGGCACGACACAGCGCGCGTCGCGCCGCGGGTCCGACACCTAC
ACGTACCTGCGCTGCTGGTACCGGATCGACGCGGATCCGCTGAAGCCGGCCTCGACCTACGAATGGGCGCGCAACCCCGC
CGGCGGCGACTGGTATCGCGTGTCCGGCTACTGGTGGGCGGACGGCATCAGGCAGTGGAAGAACATGTTCTACAGCACGA
CGTCGCAGGACGCGCTCGCCGACGTGTGCCGCAAGACGCTGGCCGCGAAAGGCATCAAGACCGACCTCGTGCAGGCGGTC
GCGGCCAACAACGCGCTGTCGTTCAACTACACGGTGTGGACCATCGATGCCGCGCAGCAGGACGCGCGCGTCAACAAGCT
GATCGTGTTCGGCGACAGCCTGTCCGACACGCAGAACATGTTCAACGCGAGCCAGTGGAAGCTGCCGAACGGCACGAGCT
GGCAGGCGGGACGCTTCAGCAACGGCCCGGTGTGGGCCGAATATCTCGCGAACACGCTGCGGCTGCCGTTCTACAACTGG
GCTATCGGTGGCGCGGCGACCGACCAGTATCTCGTCGTGCCGGGCCTCGTGCAGCAGATCGACTCGTGGCGCGAATACAT
GGATCGCGCGCCCGACTACCGGCCCGCCAACACGCTGTTCGCGGTGTTCGCAGGCGGCAACGATCTGGTGAACTACGGGC
GCTCGCCCGAGCAGGCGGCGAATGCGGTGCGCGACAGCCTCGAGCGGCTCGCCGCGGCCGGCGCGACGCGGATCATGCTC
GTCACGCTGCCGGACGTGTCGCGCGCGCCGGTGTTCGCGACCCGCACCGACACCGCGAGCGTCGCCGCGCAGGTGAAGGA
CTACAACCAGCGCCTCGCCGACGCGGCCGCCGCGCTGCGCGCCCGCTACGGCGCGACGCTGCGGCTCGAGGTGTTCGATG
CGTACGCGCTGTTCGACGACCTGCTGAGCCACCCGGCCCAGTACGGCTTCGACGACGCGAAGCGTGCATGCCTCGACATC
CCGAAACCGTCGTCGCTCACCTACCTGAGCGCGCAGACGCCGCGCGCGGACTGCCGCGATCCGGCGCGCTTCGTGTTCTG
GGACACGCTGCACCCGACCACGCGCACGCACGCGTGGCTCGCCGAGCGGATCGCGCCGTTCGTGCGTGCGCGCCTGCTGA
ACTGA

Upstream 100 bases:

>100_bases
TTTCGACAGACCGGGCCCGAGCCCGGCACTCACGGTCCCTTCCGATACACGGCCGCGCAGCCGCGCCGTCGTCCCGTCAC
AACAATCAGAAGAGGGCCGC

Downstream 100 bases:

>100_bases
CCGGCGCGGGCGGCGGTGCTTACAGCAGCGGACACGCGGTGACCTGCGTGCCGCGTTCGACGCACAGCCGCTCGTAGTCG
CGCAGGTACGCGCGCTCGTC

Product: lipolytic protein

Products: NA

Alternate protein names: TL; Atypical phospholipase; Lecithin-dependent hemolysin; LDH; Lysophospholipase; Phospholipase A2 [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MPYFRIPFSHRVAAVSAVAALGTALTLPVAQAAGPAPLPTPTGDMSLSPAGPDIVPPAASSAPGTPGTTQRASRRGSDTY
TYLRCWYRIDADPLKPASTYEWARNPAGGDWYRVSGYWWADGIRQWKNMFYSTTSQDALADVCRKTLAAKGIKTDLVQAV
AANNALSFNYTVWTIDAAQQDARVNKLIVFGDSLSDTQNMFNASQWKLPNGTSWQAGRFSNGPVWAEYLANTLRLPFYNW
AIGGAATDQYLVVPGLVQQIDSWREYMDRAPDYRPANTLFAVFAGGNDLVNYGRSPEQAANAVRDSLERLAAAGATRIML
VTLPDVSRAPVFATRTDTASVAAQVKDYNQRLADAAAALRARYGATLRLEVFDAYALFDDLLSHPAQYGFDDAKRACLDI
PKPSSLTYLSAQTPRADCRDPARFVFWDTLHPTTRTHAWLAERIAPFVRARLLN

Sequences:

>Translated_454_residues
MPYFRIPFSHRVAAVSAVAALGTALTLPVAQAAGPAPLPTPTGDMSLSPAGPDIVPPAASSAPGTPGTTQRASRRGSDTY
TYLRCWYRIDADPLKPASTYEWARNPAGGDWYRVSGYWWADGIRQWKNMFYSTTSQDALADVCRKTLAAKGIKTDLVQAV
AANNALSFNYTVWTIDAAQQDARVNKLIVFGDSLSDTQNMFNASQWKLPNGTSWQAGRFSNGPVWAEYLANTLRLPFYNW
AIGGAATDQYLVVPGLVQQIDSWREYMDRAPDYRPANTLFAVFAGGNDLVNYGRSPEQAANAVRDSLERLAAAGATRIML
VTLPDVSRAPVFATRTDTASVAAQVKDYNQRLADAAAALRARYGATLRLEVFDAYALFDDLLSHPAQYGFDDAKRACLDI
PKPSSLTYLSAQTPRADCRDPARFVFWDTLHPTTRTHAWLAERIAPFVRARLLN
>Mature_453_residues
PYFRIPFSHRVAAVSAVAALGTALTLPVAQAAGPAPLPTPTGDMSLSPAGPDIVPPAASSAPGTPGTTQRASRRGSDTYT
YLRCWYRIDADPLKPASTYEWARNPAGGDWYRVSGYWWADGIRQWKNMFYSTTSQDALADVCRKTLAAKGIKTDLVQAVA
ANNALSFNYTVWTIDAAQQDARVNKLIVFGDSLSDTQNMFNASQWKLPNGTSWQAGRFSNGPVWAEYLANTLRLPFYNWA
IGGAATDQYLVVPGLVQQIDSWREYMDRAPDYRPANTLFAVFAGGNDLVNYGRSPEQAANAVRDSLERLAAAGATRIMLV
TLPDVSRAPVFATRTDTASVAAQVKDYNQRLADAAAALRARYGATLRLEVFDAYALFDDLLSHPAQYGFDDAKRACLDIP
KPSSLTYLSAQTPRADCRDPARFVFWDTLHPTTRTHAWLAERIAPFVRARLLN

Specific function: Phospholipase hydrolyzing both fatty acid esters of phospholipid, i.e., it hydrolyzes phosphatidylcholine (PC) to lysophosphatidylcholine (LPC) and then LPC to glycerophosphorylcholine (GPC) [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: NA

Molecular weight: Translated: 49807; Mature: 49676

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYFRIPFSHRVAAVSAVAALGTALTLPVAQAAGPAPLPTPTGDMSLSPAGPDIVPPAAS
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SAPGTPGTTQRASRRGSDTYTYLRCWYRIDADPLKPASTYEWARNPAGGDWYRVSGYWWA
CCCCCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEECCEEHH
DGIRQWKNMFYSTTSQDALADVCRKTLAAKGIKTDLVQAVAANNALSFNYTVWTIDAAQQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEEECCCC
DARVNKLIVFGDSLSDTQNMFNASQWKLPNGTSWQAGRFSNGPVWAEYLANTLRLPFYNW
CCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
AIGGAATDQYLVVPGLVQQIDSWREYMDRAPDYRPANTLFAVFAGGNDLVNYGRSPEQAA
ECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHH
NAVRDSLERLAAAGATRIMLVTLPDVSRAPVFATRTDTASVAAQVKDYNQRLADAAAALR
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ARYGATLRLEVFDAYALFDDLLSHPAQYGFDDAKRACLDIPKPSSLTYLSAQTPRADCRD
HHCCCEEEEEHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCC
PARFVFWDTLHPTTRTHAWLAERIAPFVRARLLN
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYFRIPFSHRVAAVSAVAALGTALTLPVAQAAGPAPLPTPTGDMSLSPAGPDIVPPAAS
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SAPGTPGTTQRASRRGSDTYTYLRCWYRIDADPLKPASTYEWARNPAGGDWYRVSGYWWA
CCCCCCCCHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCEEEECCEEHH
DGIRQWKNMFYSTTSQDALADVCRKTLAAKGIKTDLVQAVAANNALSFNYTVWTIDAAQQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEEECCCC
DARVNKLIVFGDSLSDTQNMFNASQWKLPNGTSWQAGRFSNGPVWAEYLANTLRLPFYNW
CCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
AIGGAATDQYLVVPGLVQQIDSWREYMDRAPDYRPANTLFAVFAGGNDLVNYGRSPEQAA
ECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHCCCCHHHHH
NAVRDSLERLAAAGATRIMLVTLPDVSRAPVFATRTDTASVAAQVKDYNQRLADAAAALR
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ARYGATLRLEVFDAYALFDDLLSHPAQYGFDDAKRACLDIPKPSSLTYLSAQTPRADCRD
HHCCCEEEEEHHHHHHHHHHHHHCHHHCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCC
PARFVFWDTLHPTTRTHAWLAERIAPFVRARLLN
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3508495; 12620739; 1791426 [H]