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The map label for this gene is argM [C]

Identifier: 78067813

GI number: 78067813

Start: 3507312

End: 3508754

Strand: Direct

Name: argM [C]

Synonym: Bcep18194_A6344

Alternate gene names: 78067813

Gene position: 3507312-3508754 (Clockwise)

Preceding gene: 78067812

Following gene: 78067814

Centisome position: 94.94

GC content: 65.35

Gene sequence:

>1443_bases
ATGACGTACCGCAACGAATCTGCCTGGATCCAGCCGGCCGCACCGAGCGCCACGGCCGCCGCACCGCGCGCGACGCAGGC
GCGCACGACCGCCGAATACCGCGCGCTCGACGCCGCGCACCACATCCACCCGTTCTCGGACATGGGCGCGCTGAATCGCG
CAGGCAGCCGCGTGATCGTGAAAGCCGACGGCGTCTACCTGTGGGACTCGGACGGCAACAAGGTGATCGACGGGATGGCC
GGCCTCTGGTGCGTGAACGTCGGCTACGGCCGCAAGGAACTCGCCGACGCCGCGTATCGCCAGATCCAGGAACTGCCGTT
CTACAACACGTTCTTCAAGACCACGCACCCGCCGGTGATCGAACTCTCCGCGATGCTCGCGGAAGTCACGCCGAAGGGCT
TCAACCACTTCTTCTATTGCAACAGCGGCTCGGAAGGCAACGACACCGTGCTGCGCCTCGTGCACCAGTACTGGCGCGTG
CAGGGCCAGCCGCAGAAGAAGTTCGTGATCTCGCGCAAGAACGGCTATCACGGCTCGACGATCGCCGGCGGCACGCTCGG
CGGGATGGGCTACATGCACGAGCAGATGCCGTCGAAGGTCGAGAACATCGTGCACATCGACCAGCCGTATTTCTTCGGCG
AAGCGGCCGCCGGCGAAACGCCGGAAGCATTCGGTCTTGCCCGCGCGCAGCAACTCGAAGCGAAGATCCTCGAACTCGGC
GCGGAGAACGTCGCCGCGTTCATCGGCGAGCCGTTCCAGGGCGCGGGCGGCGTGATTTTCCCGCCGTCGACGTACTGGCC
GGAAATCCAGCGGATCTGCCGCAAGTACGACATCCTGCTGGTGGCCGACGAAGTGATCGGCGGCTTCGGCCGTACCGGCG
AATGGTTCGCACACCAGCATTTCGGCTTCGAGCCCGATCTCATCACGATGGCGAAGGGCCTCACGTCGGGTTACGTGCCG
ATGGGGGCCGTCGGCATTCACGAGCGCGTGGCGCGACCGATCATCGACAACGGTGAATTCAACCACGGCCTCACGTACTC
GGGCCACCCGGTGGCGGCAGCCGTCGCGGTCGCGAACCTGAAGCTGCTGCGCGACGAAGGGATCGTCGAGCGCGTGAAGA
ACGACACGGGCCCGTACTTCCAGGCGCTGATGCGCGAAACCTTCGCGCGTCACCCGATCGTCGGCGAGGTGCACGGCCAC
GGCCTCGTCGCGAGCCTGCAGCTCGCCGAATCGCCGGCCGAACGCCGCCGCTTCGCGAACGGCGGCGACGTCGGCACGAT
CTGCCGCGATTTCTGCTTCAACGGCAACCTGATCATGCGTGCGACCGGCGACCGGATGCTGCTGTCGCCGCCGCTCGTGA
TCTCGCGGCCGGAAATTGATGAACTCGTATCGAAGGCGAAAAAAGCAGTCGATGCAACCGCCCAGCAATTGGGTATTTCG
TAA

Upstream 100 bases:

>100_bases
TACGAAGCGTTCTTCCGCGTGATCAGCTCGTGGGAACGCCGCCATCTGCTGCTGCACGTCTGAGCGTGCACCCAACCGAA
TACGGAATCACGGAGGAAAC

Downstream 100 bases:

>100_bases
CGGTTTTGCCTATAGGCGTGCGGCGGGCGCCGCACGCCGCCATAACCAGGGGAATTCCACCATGCGTGCCTGCTTTCTTC
GCCAAGCCTGTTCCGTTGCC

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTYRNESAWIQPAAPSATAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMA
GLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPKGFNHFFYCNSGSEGNDTVLRLVHQYWRV
QGQPQKKFVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVENIVHIDQPYFFGEAAAGETPEAFGLARAQQLEAKILELG
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVP
MGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGH
GLVASLQLAESPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRPEIDELVSKAKKAVDATAQQLGIS

Sequences:

>Translated_480_residues
MTYRNESAWIQPAAPSATAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMA
GLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPKGFNHFFYCNSGSEGNDTVLRLVHQYWRV
QGQPQKKFVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVENIVHIDQPYFFGEAAAGETPEAFGLARAQQLEAKILELG
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVP
MGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGH
GLVASLQLAESPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRPEIDELVSKAKKAVDATAQQLGIS
>Mature_479_residues
TYRNESAWIQPAAPSATAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAG
LWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVIELSAMLAEVTPKGFNHFFYCNSGSEGNDTVLRLVHQYWRVQ
GQPQKKFVISRKNGYHGSTIAGGTLGGMGYMHEQMPSKVENIVHIDQPYFFGEAAAGETPEAFGLARAQQLEAKILELGA
ENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPM
GAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHG
LVASLQLAESPAERRRFANGGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRPEIDELVSKAKKAVDATAQQLGIS

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=474, Percent_Identity=26.3713080168776, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI24119277, Length=370, Percent_Identity=29.7297297297297, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI37574042, Length=379, Percent_Identity=28.2321899736148, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=376, Percent_Identity=28.4574468085106, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=26.463700234192, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226442709, Length=347, Percent_Identity=27.9538904899135, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI284507298, Length=230, Percent_Identity=30.8695652173913, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI188536080, Length=427, Percent_Identity=23.4192037470726, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI38679950, Length=427, Percent_Identity=23.4192037470726, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI38679946, Length=427, Percent_Identity=23.4192037470726, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=28.75, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786991, Length=456, Percent_Identity=28.7280701754386, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI145693181, Length=411, Percent_Identity=25.5474452554745, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=415, Percent_Identity=26.7469879518072, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789016, Length=360, Percent_Identity=25.5555555555556, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787560, Length=358, Percent_Identity=28.4916201117318, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=24.4712990936556, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=427, Percent_Identity=26.6978922716628, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=442, Percent_Identity=29.185520361991, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=371, Percent_Identity=26.4150943396226, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=303, Percent_Identity=29.3729372937294, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=445, Percent_Identity=23.8202247191011, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=454, Percent_Identity=27.9735682819383, Blast_Score=166, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=367, Percent_Identity=31.0626702997275, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=432, Percent_Identity=26.1574074074074, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21357415, Length=470, Percent_Identity=26.5957446808511, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.9655172413793, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=28.5035629453682, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=25.9770114942529, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281366494, Length=350, Percent_Identity=24.5714285714286, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24667139, Length=350, Percent_Identity=24.5714285714286, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24667143, Length=350, Percent_Identity=24.5714285714286, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 52444; Mature: 52313

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYRNESAWIQPAAPSATAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIV
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
KADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVI
EECCEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
ELSAMLAEVTPKGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGQPQKKFVISRKNGYHGST
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
IAGGTLGGMGYMHEQMPSKVENIVHIDQPYFFGEAAAGETPEAFGLARAQQLEAKILELG
CCCCCCCCHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHC
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQH
HHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHC
FGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANL
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAESPAERRRFAN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHCCCHHHHHCCC
GGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRPEIDELVSKAKKAVDATAQQLGIS
CCCHHHHHHHHHCCCCEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYRNESAWIQPAAPSATAAAPRATQARTTAEYRALDAAHHIHPFSDMGALNRAGSRVIV
CCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
KADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAAYRQIQELPFYNTFFKTTHPPVI
EECCEEEECCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHH
ELSAMLAEVTPKGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGQPQKKFVISRKNGYHGST
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
IAGGTLGGMGYMHEQMPSKVENIVHIDQPYFFGEAAAGETPEAFGLARAQQLEAKILELG
CCCCCCCCHHHHHHHHHHHHHHEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHC
AENVAAFIGEPFQGAGGVIFPPSTYWPEIQRICRKYDILLVADEVIGGFGRTGEWFAHQH
HHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHC
FGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANL
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KLLRDEGIVERVKNDTGPYFQALMRETFARHPIVGEVHGHGLVASLQLAESPAERRRFAN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHCCCHHHHHCCC
GGDVGTICRDFCFNGNLIMRATGDRMLLSPPLVISRPEIDELVSKAKKAVDATAQQLGIS
CCCHHHHHHHHHCCCCEEEEECCCEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]