Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 78067800

GI number: 78067800

Start: 3496769

End: 3498586

Strand: Direct

Name: glmS [H]

Synonym: Bcep18194_A6331

Alternate gene names: 78067800

Gene position: 3496769-3498586 (Clockwise)

Preceding gene: 78067799

Following gene: 78067801

Centisome position: 94.66

GC content: 66.78

Gene sequence:

>1818_bases
ATGTGCGGCATTGTCGGCGCAGTTGCGCAGCGTAATATCGTTCCGGTGCTGATCGAAGGATTGCGGCGCCTCGAATACCG
TGGCTACGACTCGTGCGGCGTTGCCGTGCTCGAGCCGGGCGCACCGAAGCGCGCGCGCAGCGTCGCGCGCGTCGCCGATC
TCGACGCGCAGGTGCGCGAATCGCACCTCGAAGGCACCACCGGCGTCGCGCACACCCGCTGGGCGACGCACGGCGCCCCC
GTCACGCACAACGCGCACCCGATCTTCTCGTCGAACGCGCTCGCGCTCGTCCACAACGGCATCATCGAGAACTTCGAATC
GCTGCGCGAAGCGCTGCGCGCGAAGGGCTACGAATTCGTGTCGCAGACCGACACCGAAGTGATCGCCCACCTCGTGCACA
GCCTGTATCGCGGCAACCTGTTCGACGCGGTGCGCGAAGCGGTGGGCCAGCTGCACGGCGCGTACGCGATCGCCGTGATC
CACAAGGACCAGCCGCACACCGTCGTCGGCGCGCGCCAGGGTTCGCCGCTCGTGGTCGGCCACGGCGACGGCGAGAACTT
CCTCGCCTCCGACGCGCTCGCGCTCGCGGGCAGCACCGACCGCTTCACGTTCCTCGAGGAAGGCGACGTGTGCGAGCTGT
CGCTCGACGGCGTGAAGATCGTCGACCGCGACGGCGCGCTCGCGCAGCGCGAGATCCGCGTGGTCAGCGCCTACGGCGGC
GCAGTCGAACTCGGGCCGTATCGCCACTTCATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGATCAGCGACACCGTGCC
GCAAACGGACGCGTTCGACGCGACGCTGTTCGGTGACGCCGCGCCCGCCGCGTTCGCGGAAATCGACAGCCTGCTGATCC
TCGCGTGCGGCACGAGCTACTACTCGGGGTTGACCGCGAAATACTGGCTTGAATCGATCGCGAAGATCCCGACGCAGGTC
GAGATCGCGAGCGAATACCGCTACCGCGAATCGGTGCCGAACCCGCGCCAGCTTGTGCTGGTAATCTCGCAATCGGGCGA
GACGGCCGATACGCTCGCGGCGCTCAAGCACGCGCAGTCGCTCGGCCATACGCACACGCTGGCGGTCTGCAACGTCGCGA
CGAGCGCGATGGTGCGCCTCACCGAAATGCAGTTCCTGACGCACGCGGGCACCGAGATCGGCGTCGCATCGACGAAGGCG
TTCACGACGCAGCTCGTCGCGCTGTTCGTGCTGGCGGCCACGCTCGGCAAGCTGCGCGGGCACGTCGATGCCGCGCAGGA
AGCCGAATTCCTGAAGCAGCTGCGCCACCTGCCGGCCGCACTGAACAGCGTGCTCGCACTCGAGCCGCAGATCATCGCGT
GGTCGGAGGAATTCGCACGCAAGGAAAACGCACTGTTCCTCGGCCGCGGGCTGCACTACCCGATCGCGCTCGAAGGCGCG
TTGAAGCTGAAGGAAATCTCGTACATCCACGCCGAGGCCTATCCGGCCGGCGAACTGAAGCACGGGCCACTCGCGCTCGT
CACGGAAGCGATGCCGGTCATCACGGTCGCGCCGAACGACACGCTGCTCGAGAAGCTGAAGTCGAACATGCAGGAAGTGC
GTGCGCGCGGCGGTGAGTTGTACGTGTTCGCCGATGCCGATACGCAGATCGTCAACGACGACGGCCTGCACGTGATCCGG
ATGCCGGAGCATTACGGGCAACTGTCGCCGATCCTGCACGTCGTGCCGCTGCAATTGCTCGCGTATCACACCGCGTGCGC
GCGCGGCACCGACGTCGACAAGCCGCGGAACCTCGCGAAATCGGTGACGGTGGAGTAA

Upstream 100 bases:

>100_bases
ACCGCAAAGAGCGGCTACGTCCGCCCGGTCAAGAAGAAAAGCTGAACCTTTTGCGGGCGCCCTGGCGGCGTCTGCATCGA
CTTACAGGACTGACTCATTC

Downstream 100 bases:

>100_bases
AACCGGTCGCCGGGATGGCCCCTGCCGGGCCGTCCCGGGCGCGTACCGGCGTGAAGCAGGCCATTCGGCCAGGTCGAAAT
ATATACCACGTAGTGGTATA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVRESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFESLREALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVGQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRDGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAISDTVPQTDAFDATLFGDAAPAAFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVRESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFESLREALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVGQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRDGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAISDTVPQTDAFDATLFGDAAPAAFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVRESHLEGTTGVAHTRWATHGAP
VTHNAHPIFSSNALALVHNGIIENFESLREALRAKGYEFVSQTDTEVIAHLVHSLYRGNLFDAVREAVGQLHGAYAIAVI
HKDQPHTVVGARQGSPLVVGHGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRDGALAQREIRVVSAYGG
AVELGPYRHFMQKEIFEQPRAISDTVPQTDAFDATLFGDAAPAAFAEIDSLLILACGTSYYSGLTAKYWLESIAKIPTQV
EIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQSLGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKA
FTTQLVALFVLAATLGKLRGHVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGELYVFADADTQIVNDDGLHVIR
MPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=686, Percent_Identity=35.8600583090379, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI205277386, Length=685, Percent_Identity=36.4963503649635, Blast_Score=376, Evalue=1e-104,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=55.1554828150573, Blast_Score=649, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=229, Percent_Identity=28.3842794759825, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539970, Length=718, Percent_Identity=34.1225626740947, Blast_Score=349, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17532899, Length=430, Percent_Identity=37.6744186046512, Blast_Score=273, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17532897, Length=430, Percent_Identity=37.6744186046512, Blast_Score=272, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=36.5256124721604, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=29.8611111111111, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.2745098039216, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323958, Length=172, Percent_Identity=29.0697674418605, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=35.9124087591241, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI28573187, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24659598, Length=258, Percent_Identity=27.1317829457364, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24659604, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65471; Mature: 65471

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
SHLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFESLREALRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVGQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRDGALAQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCCHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAISDTVPQTDAFDATLFGDAAPAAFAEIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEECCCCCCHHHHHHHHEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEPGAPKRARSVARVADLDAQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
SHLEGTTGVAHTRWATHGAPVTHNAHPIFSSNALALVHNGIIENFESLREALRAKGYEFV
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGNLFDAVREAVGQLHGAYAIAVIHKDQPHTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCCCEEEEE
HGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDGVKIVDRDGALAQREIRVVSAYGG
CCCCCCHHHHCHHHCCCCCCCEEEECCCCEEEEEECCEEEEECCCCCCHHHEEEEEECCC
AVELGPYRHFMQKEIFEQPRAISDTVPQTDAFDATLFGDAAPAAFAEIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEECCCCCCHHHHHHHHEEEEEECCHH
YSGLTAKYWLESIAKIPTQVEIASEYRYRESVPNPRQLVLVISQSGETADTLAALKHAQS
HCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHTHTLAVCNVATSAMVRLTEMQFLTHAGTEIGVASTKAFTTQLVALFVLAATLGKLRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
HVDAAQEAEFLKQLRHLPAALNSVLALEPQIIAWSEEFARKENALFLGRGLHYPIALEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVITVAPNDTLLEKLKSNMQEVRARGGEL
EEEHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTQIVNDDGLHVIRMPEHYGQLSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]