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The map label for this gene is glmU [H]

Identifier: 78067799

GI number: 78067799

Start: 3495352

End: 3496713

Strand: Direct

Name: glmU [H]

Synonym: Bcep18194_A6330

Alternate gene names: 78067799

Gene position: 3495352-3496713 (Clockwise)

Preceding gene: 78067798

Following gene: 78067800

Centisome position: 94.62

GC content: 68.58

Gene sequence:

>1362_bases
ATGAATATCGTGATTTTGGCGGCAGGCACCGGCAAGCGCATGCGTTCCGCGCTGCCGAAAGTGCTCCATCCCCTGGCCGG
CAGGCCGCTCCTCTCCCACGTCATCGACACCGCGCGCACGCTGCAGCCGTCCCGGCTCGTCGTCGTCGTCGGTCACGGCG
CCGAGCAGGTTCAGGCAGCCGTCGCCGCCCCTGACGTCCAGTTTGCCGTGCAGGCCGAACAGTTGGGCACCGGCCACGCG
GTGCGCCAGGCGCTGCCGCTCCTCGATCCCGCGCAACCGACGCTCGTGCTGTACGGCGACGTGCCGCTCACGCGCGCGTC
GACGCTGCAGCGCCTCGTCGACGCCGCGCGCGAGGGCCGCTACGGGATTCTGACCGTCACACTCGACGATCCGACCGGCT
ATGGCCGCATCGTGCGCGACGCGGCCGGCTTCGTCACGCGCATCGTCGAACAGAAGGACGCGTCGCCCGAGCAGTTGAAG
ATCGCCGAGATCAACACCGGCATCATCGTCACGCCGACGGCACAGCTGTCGATGTGGCTCGGCGCGCTGAAGAACGAGAA
CGCGCAGGGCGAGTACTACCTGACCGACGTCGTCGAACTCGCGATCGAGGCCGGTTTCGAGGTCGTCACCGCGCAGCCCG
ACGAGGAATGGGAGACGCTCGGCGTGAACAGCAAGGCGCAGCTCGCCGAGCTCGAGCGCATCCACCAGCGCAATATCGCC
GAAGCCCTGCTCGTCGACGGCGTCACGCTCGCCGATCCGGCGCGCCTCGACGTGCGCGGCACGCTGCGCTGCGGCCGCGA
CGTGTCGATCGACGTGAACTGCGTGTTCGAAGGCAACGTGACGCTCGCCGACAACGTGACGATCGGCGCGAACTGCGTGA
TCCGCAACGCGTCGGTCGGCGCCGGCACGCGCATCGACGCGTTCACGCACATCGACGGCGCCGAGCTCGGCGCGCACACC
GTGATCGGCCCGTACGCGCGGCTGCGCCCCGGCGCGCAGCTCGCGGACGAAGCGCACGTCGGCAACTTCGTCGAGGTGAA
GAACGCGGTGATCGGCCACGGCTCGAAGGCGAACCACCTGACGTACATCGGCGACGCCGACATCGGCGCGCGCGTGAACA
TCGGCGCCGGCACGATCACCTGCAACTACGACGGCGCGAACAAGTTCCGCACCGTGATCGAGGACGACGTGTTCGTCGGC
TCCGACACGCAGCTCGTCGCGCCCGTGCGCGTCGGCCGTGGCGTGACGATCGCCGCCGGCACGACGATCTGGAAGGACGT
AGCCGACGGCTTGCTCGCATTGAACGAGAAGACGCAGACCGCAAAGAGCGGCTACGTCCGCCCGGTCAAGAAGAAAAGCT
GA

Upstream 100 bases:

>100_bases
GGCCTCTTTCCGGCGCTGTCGCCCCGCCGCGACAGGCCCGGAACGGCGGGGGCCGCATGCTAAAATAGGCGGCTTCGAAC
TCCTCTGACAAGCTGGCGCC

Downstream 100 bases:

>100_bases
ACCTTTTGCGGGCGCCCTGGCGGCGTCTGCATCGACTTACAGGACTGACTCATTCATGTGCGGCATTGTCGGCGCAGTTG
CGCAGCGTAATATCGTTCCG

Product: glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAAVAAPDVQFAVQAEQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGRYGILTVTLDDPTGYGRIVRDAAGFVTRIVEQKDASPEQLK
IAEINTGIIVTPTAQLSMWLGALKNENAQGEYYLTDVVELAIEAGFEVVTAQPDEEWETLGVNSKAQLAELERIHQRNIA
EALLVDGVTLADPARLDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVGAGTRIDAFTHIDGAELGAHT
VIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGRGVTIAAGTTIWKDVADGLLALNEKTQTAKSGYVRPVKKKS

Sequences:

>Translated_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAAVAAPDVQFAVQAEQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGRYGILTVTLDDPTGYGRIVRDAAGFVTRIVEQKDASPEQLK
IAEINTGIIVTPTAQLSMWLGALKNENAQGEYYLTDVVELAIEAGFEVVTAQPDEEWETLGVNSKAQLAELERIHQRNIA
EALLVDGVTLADPARLDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVGAGTRIDAFTHIDGAELGAHT
VIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGRGVTIAAGTTIWKDVADGLLALNEKTQTAKSGYVRPVKKKS
>Mature_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAAVAAPDVQFAVQAEQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGRYGILTVTLDDPTGYGRIVRDAAGFVTRIVEQKDASPEQLK
IAEINTGIIVTPTAQLSMWLGALKNENAQGEYYLTDVVELAIEAGFEVVTAQPDEEWETLGVNSKAQLAELERIHQRNIA
EALLVDGVTLADPARLDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVGAGTRIDAFTHIDGAELGAHT
VIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGRGVTIAAGTTIWKDVADGLLALNEKTQTAKSGYVRPVKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=57.0796460176991, Blast_Score=509, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep; PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48063; Mature: 48063

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAA
CEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VAAPDVQFAVQAEQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGR
HCCCCEEEEEEHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
YGILTVTLDDPTGYGRIVRDAAGFVTRIVEQKDASPEQLKIAEINTGIIVTPTAQLSMWL
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECHHHHHHHH
GALKNENAQGEYYLTDVVELAIEAGFEVVTAQPDEEWETLGVNSKAQLAELERIHQRNIA
HHHCCCCCCCCEEHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
EALLVDGVTLADPARLDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVG
HHHHHCCEEECCCCCCCEEEEEECCCCCEEEEEEEEECCEEEECCEEECCEEEEEECCCC
AGTRIDAFTHIDGAELGAHTVIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHL
CCCEEEEEEECCCCCCCCCCEECCHHHCCCCCHHCCHHHCCCHHEECHHHCCCCCCCCEE
TYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGRGVTIAAG
EEEECCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEC
TTIWKDVADGLLALNEKTQTAKSGYVRPVKKKS
CHHHHHHHHHHEEECCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAA
CEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
VAAPDVQFAVQAEQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGR
HCCCCEEEEEEHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
YGILTVTLDDPTGYGRIVRDAAGFVTRIVEQKDASPEQLKIAEINTGIIVTPTAQLSMWL
EEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECHHHHHHHH
GALKNENAQGEYYLTDVVELAIEAGFEVVTAQPDEEWETLGVNSKAQLAELERIHQRNIA
HHHCCCCCCCCEEHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
EALLVDGVTLADPARLDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVG
HHHHHCCEEECCCCCCCEEEEEECCCCCEEEEEEEEECCEEEECCEEECCEEEEEECCCC
AGTRIDAFTHIDGAELGAHTVIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHL
CCCEEEEEEECCCCCCCCCCEECCHHHCCCCCHHCCHHHCCCHHEECHHHCCCCCCCCEE
TYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGRGVTIAAG
EEEECCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEC
TTIWKDVADGLLALNEKTQTAKSGYVRPVKKKS
CHHHHHHHHHHEEECCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA