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The map label for this gene is 78067783

Identifier: 78067783

GI number: 78067783

Start: 3478537

End: 3479433

Strand: Reverse

Name: 78067783

Synonym: Bcep18194_A6314

Alternate gene names: NA

Gene position: 3479433-3478537 (Counterclockwise)

Preceding gene: 78067785

Following gene: 78067781

Centisome position: 94.19

GC content: 67.34

Gene sequence:

>897_bases
ATGTCGTTTGAGGCGTTTGCACCGTTTCGCGTGACGGTGCAGGACACCGACATTTTCGGTGTCAAAGGAGGCGCGGGTCC
GCCGCTCCTGTTGCTGCACGGACATCCGCAAACCCACATGATCTGGCATCGCGTTGCCGCGACGCTCGCGAATCATTTCA
CGGTGATTGCCACCGACCTGCGCGGTTACGGCGCGTCGGGCAAGCCGCCGAGCGACGCGCAGCATGCGCCGTATTCGAAA
CGTGCGATGGCGGCCGACCAGGTCGCCGTGATGCGGCATTTCGGCTTCGAGCACTTCCATGTGTGCGCGCACGATCGCGG
CGCGCGGGTCGCGCACCGGCTGGCGCTCGATCACGCGGACGCCGTCGAGCGGATGATGCTGCTCGACATCGCACCGACGC
TCGCGATGTACGAGAAAACCGATCGCGCGTTCGCGACCGCGTATTTCCACTGGTTCTTCCTGATCCAGCCAGAGCCGCTG
CCCGAAACGCTGGTCGGCGCGCATACCGATGCGTACATCGAGCGCGTGATGGGCAACCGGTCCGCCGGGCTCGCGCCGTT
CGCGCCCGAGGCGCTCGCCGCGTACCGGGCCGCGCTCGCGCAGCCGGGCGCCGTGCATGCGATGTGCGAGGACTACCGCG
CATCCGCGACGATCGATCTCGAGCACGACCGTGCGGATCTCGAGCGTGGCAACAAGGTCGCGTGTCCGCTGCGCGTGCTG
TGGGGCGAGCACGGCATCGTCGGCCGTTGCTTCGATCCGCTCGACGAATGGCGCCGCGTTGCGCGCGACGTCAGCGGTCG
TGCGCTCGAGTGCGGGCACTACATTCCGGAAGAGGCGCCTGTCGCGCTGATCGACGAACTGTTGGCCTTCTTCGAGGCGC
GCGACGCGGCTGCGTGA

Upstream 100 bases:

>100_bases
GTGAGTGTTCTCTTTCTAGGGATTCTGGCTGTTGCCCCGCTGTGCAGAGGCGCAAGCGCTCCTAAAATAGCCGCCATAAC
AAACCAACGAGAAACAAACC

Downstream 100 bases:

>100_bases
CGCTGCGCGCGGGCACGCGGGCGGCGCGTGTACCCGCCAGTCAGCGGTGCGCGCCGTCGTCTTCGACGAGCGGCGGCAGC
CGGCGCGGCACCGGCGTCGA

Product: Alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSFEAFAPFRVTVQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSK
RAMAADQVAVMRHFGFEHFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPL
PETLVGAHTDAYIERVMGNRSAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
WGEHGIVGRCFDPLDEWRRVARDVSGRALECGHYIPEEAPVALIDELLAFFEARDAAA

Sequences:

>Translated_298_residues
MSFEAFAPFRVTVQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSK
RAMAADQVAVMRHFGFEHFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPL
PETLVGAHTDAYIERVMGNRSAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
WGEHGIVGRCFDPLDEWRRVARDVSGRALECGHYIPEEAPVALIDELLAFFEARDAAA
>Mature_297_residues
SFEAFAPFRVTVQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSKR
AMAADQVAVMRHFGFEHFHVCAHDRGARVAHRLALDHADAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLP
ETLVGAHTDAYIERVMGNRSAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVLW
GEHGIVGRCFDPLDEWRRVARDVSGRALECGHYIPEEAPVALIDELLAFFEARDAAA

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=283, Percent_Identity=28.2685512367491, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI13376164, Length=283, Percent_Identity=28.2685512367491, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI218777837, Length=247, Percent_Identity=23.4817813765182, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554012, Length=221, Percent_Identity=24.4343891402715, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562298, Length=222, Percent_Identity=22.972972972973, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32853; Mature: 32722

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEAFAPFRVTVQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDL
CCCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGKPPSDAQHAPYSKRAMAADQVAVMRHFGFEHFHVCAHDRGARVAHRLALDHAD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLPETLVGAHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCC
SAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCCEEE
WGEHGIVGRCFDPLDEWRRVARDVSGRALECGHYIPEEAPVALIDELLAFFEARDAAA
ECCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFEAFAPFRVTVQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDL
CCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGKPPSDAQHAPYSKRAMAADQVAVMRHFGFEHFHVCAHDRGARVAHRLALDHAD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPEPLPETLVGAHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCHHHHHHHHHHCCC
SAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVL
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCCEEE
WGEHGIVGRCFDPLDEWRRVARDVSGRALECGHYIPEEAPVALIDELLAFFEARDAAA
ECCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA