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The map label for this gene is dppA [H]

Identifier: 78067735

GI number: 78067735

Start: 3425920

End: 3427515

Strand: Direct

Name: dppA [H]

Synonym: Bcep18194_A6266

Alternate gene names: 78067735

Gene position: 3425920-3427515 (Clockwise)

Preceding gene: 78067734

Following gene: 78067736

Centisome position: 92.74

GC content: 65.23

Gene sequence:

>1596_bases
ATGCAGGTCAAGCTGTTCGCCGCGGCCACGCTCGCCGCCGCCCTCGCCGCCCCCGGCCTCGCCGCCGCCAAGCCGCTCAC
CGTGTGCACGGAATCGAGCCCGGACGGCTTCGACGTCGTGCAGTACAACTCGCTCGTCACGACCAACGCATCGGCCGACG
TGATCTTCAACACGCTCGTGTCGTACGACGAAGCCGCGAAGAAAGTCGTGCCCGCGCTCGCCGACAAATGGGACGCGAGC
GCAGACGGCCTCACGTACACGTTCCACCTGCGCCCGAACGTCGCGTTCCAGACCACCGACTATTTCAAGCCGAGCCGCTC
GCTCGACGCGGACGACGTCGTGTTCACGTTCTCGCGGATGCTCGACGATTCGAACCCGTGGCACAAGGTGGCCGGTGCAA
GCGGCTTCCCGCACGCGCAGTCGATGAGCCTCGTGAAGCTCGTGAAGTCGGTCACGAAGGTCGACGACAGCACCGTGAAG
TTCGTGCTGAACGAGCCGAACGCGACGTTCGTGCCGATCCTGACGATGGGCTTCGCGTCGATCTACTCGGCCGAATACGC
GGACCAGTTGCTGAAGGCCGGCAAGCAGGCCGACCTGAACGCGAAGCCGGTCGGCACCGGCCCGTTCGTGCTGAAGAGCT
ACACGAAGGACGCGCTGATCCGCTACGACGCGAACCCGACCTACTGGGGCACGAAGCCGAAGGTCGACCGGCTGATCTAC
GCGATCACGCCCGACCCGTCGGTGCGCCTGCAGAAGGTGAAGGCCGGCGAATGCCAGATCGCGCTGTCACCGAAGCCGCA
GGACGTGCTCGCCGCAAAGGGTGAAAGTGCGCTGAAGGTCGTGCAGACGCCCGCGTTCATGACCGCGTTCGTCGCGCTGA
ACACGCAGAAGAAGCCGCTCGACAACGACAAAGTGCGCGAAGCGCTGAACCTCGCGTTCGACCGCGCGACCTACCTGAAG
GTCGTGTTCGACAACACCGCGACGGCCGCGAACAACCCGTATCCGCCGAACACGTGGAGCTACGCGAAGGACGTCGCGCC
GTACGCATACGATCCTGCAAAGGCGAAGCAGCTGCTCGCGCAGGCCGGCTTCCCGAACGGCTTCTCGACGACGATCTGGA
CGCGCCCGACCGGCAGCGTGCTGAACCCGAACCCGAAGGTCGGCGCGGAGCTGCTGCAGGCCGACCTCGCGAAGATCGGC
GTGAAGGCCGAGGTCAAGGTGATCGAATGGGGCGAGCTGATCAAGCAGGCGAAGCTCGGCCAGCATGACATGCTGTTCAT
GGGCTGGGCCGGCGACAACGGTGATCCGGACAACTACCTGTCGCCGCTGTTCAGCTGCAACGCGGTGAAGTCGGGCATCA
ACTTCGCGCGCTTCTGCGACACGCAGCTCGACAAGCTGATCGCCGACGGCAAATCGACCGCCGACCAGGCCAAGCGCGCG
AAGCTGTATGAAGCCGCGCAGAAGATCATCCACGACCAGGCGCTGTGGATTCCGCTCGGCTACCCGACCGCGGCCGCGCT
CACGCGCACAAACGTGAGCGGCTATCACGTGAGCCCGTTCGGGCGGCAGAACTTCACGTCCGTCGCGGTGCAGTAA

Upstream 100 bases:

>100_bases
TGACGGTATGCTATTCGCCAGCCGCGCCGGCCCTGTCCGCTTCCGGGCCGCGCCCGCATCCCGTCACCCAGCAAAAAACA
CAAGCCACGTGGGAGATCCT

Downstream 100 bases:

>100_bases
CGCGACCCTCGCGCGTGGCGCGCAAGCGACGGTGCGTCGGGCCGTCGCTTGCGGCCCGCGCGCCGCGCTTGCTACACTGC
GCGCTCATTCCTCATACCGG

Product: ABC peptide transporter, periplasmic ligand binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MQVKLFAAATLAAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDAS
ADGLTYTFHLRPNVAFQTTDYFKPSRSLDADDVVFTFSRMLDDSNPWHKVAGASGFPHAQSMSLVKLVKSVTKVDDSTVK
FVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDRLIY
AITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDTQLDKLIADGKSTADQAKRA
KLYEAAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTSVAVQ

Sequences:

>Translated_531_residues
MQVKLFAAATLAAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDAS
ADGLTYTFHLRPNVAFQTTDYFKPSRSLDADDVVFTFSRMLDDSNPWHKVAGASGFPHAQSMSLVKLVKSVTKVDDSTVK
FVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDRLIY
AITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDTQLDKLIADGKSTADQAKRA
KLYEAAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTSVAVQ
>Mature_531_residues
MQVKLFAAATLAAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDAS
ADGLTYTFHLRPNVAFQTTDYFKPSRSLDADDVVFTFSRMLDDSNPWHKVAGASGFPHAQSMSLVKLVKSVTKVDDSTVK
FVLNEPNATFVPILTMGFASIYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDRLIY
AITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLK
VVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLAQAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIG
VKAEVKVIEWGELIKQAKLGQHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDTQLDKLIADGKSTADQAKRA
KLYEAAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTSVAVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=44.0839694656489, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1787551, Length=502, Percent_Identity=34.6613545816733, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1787052, Length=523, Percent_Identity=31.7399617590822, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1789887, Length=504, Percent_Identity=25.5952380952381, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787762, Length=480, Percent_Identity=24.7916666666667, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=24.30426716141, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081878, Length=528, Percent_Identity=25, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789397, Length=535, Percent_Identity=24.8598130841122, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57497; Mature: 57497

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKLFAAATLAAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVVPALADKWDASADGLTYTFHLRPNVAFQTTDYFKPSRSLDADDVVFTFSRM
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHH
LDDSNPWHKVAGASGFPHAQSMSLVKLVKSVTKVDDSTVKFVLNEPNATFVPILTMGFAS
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHH
IYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEE
AITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCCEEEEEECCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCCCCC
DNDKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
QAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIGVKAEVKVIEWGELIKQAKLG
HCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDTQLDKLIADGKSTADQAKRA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
KLYEAAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTSVAVQ
HHHHHHHHHHCCCEEEEEECCCCHHHHEECCCCCEEECCCCCCCCEEEECC
>Mature Secondary Structure
MQVKLFAAATLAAALAAPGLAAAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLV
CEEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHH
SYDEAAKKVVPALADKWDASADGLTYTFHLRPNVAFQTTDYFKPSRSLDADDVVFTFSRM
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHH
LDDSNPWHKVAGASGFPHAQSMSLVKLVKSVTKVDDSTVKFVLNEPNATFVPILTMGFAS
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEHHHHHHHHH
IYSAEYADQLLKAGKQADLNAKPVGTGPFVLKSYTKDALIRYDANPTYWGTKPKVDRLIY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEE
AITPDPSVRLQKVKAGECQIALSPKPQDVLAAKGESALKVVQTPAFMTAFVALNTQKKPL
EECCCCCCEEEEEECCCEEEEECCCCHHHHHCCCCCHHHHHCCCHHHHHHHEECCCCCCC
DNDKVREALNLAFDRATYLKVVFDNTATAANNPYPPNTWSYAKDVAPYAYDPAKAKQLLA
CHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHH
QAGFPNGFSTTIWTRPTGSVLNPNPKVGAELLQADLAKIGVKAEVKVIEWGELIKQAKLG
HCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHCC
QHDMLFMGWAGDNGDPDNYLSPLFSCNAVKSGINFARFCDTQLDKLIADGKSTADQAKRA
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
KLYEAAQKIIHDQALWIPLGYPTAAALTRTNVSGYHVSPFGRQNFTSVAVQ
HHHHHHHHHHCCCEEEEEECCCCHHHHEECCCCCEEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]