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The map label for this gene is moeB [H]

Identifier: 78067657

GI number: 78067657

Start: 3335118

End: 3335933

Strand: Direct

Name: moeB [H]

Synonym: Bcep18194_A6188

Alternate gene names: 78067657

Gene position: 3335118-3335933 (Clockwise)

Preceding gene: 78067656

Following gene: 78067665

Centisome position: 90.28

GC content: 67.4

Gene sequence:

>816_bases
ATGGCCCGTTTTTCATGCGCGCCTAAAATAACGACACCTCCGCCGCCTCGCCCACGACTCCCCATGAACGACGATCAACT
CCTTCGCTACTCCCGTCACATCCTCGTCGACGAAATCGGCATCGAGGCGCAGCAGCGCTTTCTCGATGCGCATGCGATCG
TGGTCGGCGCGGGGGGCCTCGGCTCACCCGCCGCGATGTACCTCGCGGCATCAGGCGTCGGCACGATCACGCTCGTCGAC
GCCGATACGGTCGACCTCACGAACCTGCAGCGGCAGATCCTGCACGTGACGGCATCGGTCGGCCGCCACAAGGTCGAATC
GGGGCGCGACGCGCTCGCCCAGCTGAACCCCGACGTGAAGGTGAACGCGGTCGCGGAGCGCGTCGACGACGCGTGGCTCG
ACGCGCACGTGCCGCATGCGACCGTCGTGCTCGACTGCACCGACAACTTCGCGACGCGGCATGCGATCAACCGCGCGTGC
GTCGCGCACGGCGTGCCGCTCGTGTCGGGCGCCGCGCTGCGTTTCGACGGCCAGATCAGCACGTTCGATTTCCGCGACCC
GGCCGCGCCCTGCTATGCGTGCGTGTTTCCGGAAGACCAGCCGTTCGAGGAAGTCGCGTGCGCGACGATGGGCGTGTTCG
CGCCGACGGTCGGGATCATCGGCGCAATGCAGGCCGCCGAGGCGCTGCGCGTGATCGGCGAAATCGGCAAGACGCTCAAC
GGCCGGCTGATGATGCTCGATTCACTGCGGATGGAATGGACGACGATGAAAATCGCGCGCCAGGCCGACTGCCCCGTGTG
CGGGGGCCGGCACTGA

Upstream 100 bases:

>100_bases
CATCGGGCGCAAGCGCGAAGCCGGCAGCCGCACCGAAGCCCGCGTCAGCGCCGCAGTAAGCGCCGGCCGGCATCCGACGG
GCCATCGCGGGAAGACCGCG

Downstream 100 bases:

>100_bases
CGCGCGACGGGCATGCGCCGGGCGGCGCATGCTTGGTGACACTTCGCTACGATTAGCGGCGCCGCCCGCGCGTCAAGCAG
CCGCGTCCGCGCGCGGCTCC

Product: molybdopterin biosynthesis protein MoeB

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MARFSCAPKITTPPPPRPRLPMNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTITLVD
ADTVDLTNLQRQILHVTASVGRHKVESGRDALAQLNPDVKVNAVAERVDDAWLDAHVPHATVVLDCTDNFATRHAINRAC
VAHGVPLVSGAALRFDGQISTFDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGEIGKTLN
GRLMMLDSLRMEWTTMKIARQADCPVCGGRH

Sequences:

>Translated_271_residues
MARFSCAPKITTPPPPRPRLPMNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTITLVD
ADTVDLTNLQRQILHVTASVGRHKVESGRDALAQLNPDVKVNAVAERVDDAWLDAHVPHATVVLDCTDNFATRHAINRAC
VAHGVPLVSGAALRFDGQISTFDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGEIGKTLN
GRLMMLDSLRMEWTTMKIARQADCPVCGGRH
>Mature_270_residues
ARFSCAPKITTPPPPRPRLPMNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGLGSPAAMYLAASGVGTITLVDA
DTVDLTNLQRQILHVTASVGRHKVESGRDALAQLNPDVKVNAVAERVDDAWLDAHVPHATVVLDCTDNFATRHAINRACV
AHGVPLVSGAALRFDGQISTFDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGEIGKTLNG
RLMMLDSLRMEWTTMKIARQADCPVCGGRH

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=262, Percent_Identity=40.4580152671756, Blast_Score=177, Evalue=8e-45,
Organism=Homo sapiens, GI4885649, Length=145, Percent_Identity=34.4827586206897, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=44, Blast_Score=224, Evalue=3e-60,
Organism=Escherichia coli, GI87082356, Length=252, Percent_Identity=44.047619047619, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1789177, Length=159, Percent_Identity=37.7358490566038, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540406, Length=258, Percent_Identity=39.1472868217054, Blast_Score=193, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI193203301, Length=164, Percent_Identity=27.4390243902439, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI86565431, Length=133, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI86565433, Length=133, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=254, Percent_Identity=35.0393700787402, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6322639, Length=160, Percent_Identity=28.125, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320598, Length=169, Percent_Identity=26.6272189349112, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582879, Length=251, Percent_Identity=39.0438247011952, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24660640, Length=158, Percent_Identity=32.2784810126582, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR012730
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 29102; Mature: 28971

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFSCAPKITTPPPPRPRLPMNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCC
GSPAAMYLAASGVGTITLVDADTVDLTNLQRQILHVTASVGRHKVESGRDALAQLNPDVK
CCCHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNAVAERVDDAWLDAHVPHATVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIS
EHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEE
TFDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGEIGKTLN
EECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRLMMLDSLRMEWTTMKIARQADCPVCGGRH
CEEEEEECCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARFSCAPKITTPPPPRPRLPMNDDQLLRYSRHILVDEIGIEAQQRFLDAHAIVVGAGGL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCC
GSPAAMYLAASGVGTITLVDADTVDLTNLQRQILHVTASVGRHKVESGRDALAQLNPDVK
CCCHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VNAVAERVDDAWLDAHVPHATVVLDCTDNFATRHAINRACVAHGVPLVSGAALRFDGQIS
EHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCEEEECCCEE
TFDFRDPAAPCYACVFPEDQPFEEVACATMGVFAPTVGIIGAMQAAEALRVIGEIGKTLN
EECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRLMMLDSLRMEWTTMKIARQADCPVCGGRH
CEEEEEECCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503 [H]