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The map label for this gene is ctaC [H]

Identifier: 78067645

GI number: 78067645

Start: 3324639

End: 3326234

Strand: Reverse

Name: ctaC [H]

Synonym: Bcep18194_A6176

Alternate gene names: 78067645

Gene position: 3326234-3324639 (Counterclockwise)

Preceding gene: 78067646

Following gene: 78067644

Centisome position: 90.04

GC content: 64.22

Gene sequence:

>1596_bases
ATGGAAATTTTGGGTAAGGATGCTATGAAAACAATCAAGCGAGCCCTCACGGGCGTGCTGGCATGCAGCGGATTGCTCTT
TGCCGGTGCCGCCCTGGCGGTCGGTGATAGCCCGGGCGGCCCCCGCGTCAACGAGATCAACTTTCAGCCGCCTGTCACGA
AGATCGCCGAGGAGCTCTACGATCTCCACACGATGATGCTCATCCTGTGTACGGTGATCTTCGTCGGCGTGTTCGGCGTG
ATGTTCTATTCGATCTTCGCGCACCGCAAATCCAAGGGCCACAAGGCCGCCAATTTCCATGAAAGCACGACCGTCGAGAT
CATCTGGACGATCGTGCCGTTCGTCATCGTCGTGCTGATGGCGCTGCCGGCGACGAAGGCCGTCGTCGCGATGAAGGACA
CGACCAACGCCGATCTCACGATCAAGGTTACCGGCTACCAGTGGAAGTGGGGCTACGACTACGTGAAGGGCCCGGGCGAG
GGCATCGGCTTCCTGTCGACGCTCAGCACCCCGCGTGACGAAGTGATGGGCAAGAAGCCGATCACCGACACCTATCTGCA
GGAAGTCGACAACCCGCTCGTCGTGCCGGTCAACAAGAAGATCCGCATCATCACGACCGCGAACGACGTCGTCCACTCGT
GGTACGTGCCCGCGTTCGGCGTGAAGCAGGATGCGATCCCCGGCTTCGTGCGCGACACGTGGTTCAAGGCCGACAAGGTC
GGTACGTTCCGCGGTTTCTGTACCGAGCTGTGCGGCAAGGAACACGCGTACATGCCGGTCGTCGTCGAAGTCCTGTCGGA
TGACGACTACGCGAAGTGGGTCACCGCGCAGAAGGCCAAGCTGGCCAGCGCCGCAGTCGATCCGAACAAGGTCTACACGA
TGGCTGAACTCGTCGCGCACGGCGAGGAAGTCTACAAGGCGAACTGCGCGGCCTGCCACCAGGTGAGCGGCAAGGGCCTC
GGCGCCTTCCCGGCCATGGACGGCAGCCCGATCGTGAACGGCCCGATCGCCGGCCACGTCGAGCGCGTGCTGCACGGCAA
GGGTGCAATGCCGTCGTGGGCGTCGCTGTCGGATCTCGACATCGCGTCGGTCATCACGTACGAACGCAATTCGTGGGGCA
ACCACAAGAACGACCTGCTGCAGCCGAAGCAAGTGGCCGACGCGCGTAACGGCAAGATGCCGGAAGACGCGGCGGGCGCA
GCGGCAGCGGCACCGGCGGAAGCCGCTTCGGCGCCGGCGCAAGCCGCGTCGGGTGCAGAGCAGCCGGCGGCAGCGGCATC
GGCCGCACTGTCGACGATCTACTTCGAGACGGGCAAGAGCGTGCTGCCGGCCGACGCGAAAGCGGCGATCGCCGCCGCGG
CCGACTATGCGAAGGCACATCCGGACGCGAAGCTCGCGCTGTCGGGCTTTACCGACAAGTCGGGCTCGGCCGACGCAAAC
GCCGAACTGGCGAAGCATCGCGCACAAGCCGTGCGCGACGCGCTGAAGGCAGCAGGCGTGGCGGAAGACCACATTATTCT
CAAAAAGCCGGAAACGATCACGGGCGGGGCTGACGCGAAGGAAGCCCGGCGTGTCGAGATCGGCCCGGCGGCTTGA

Upstream 100 bases:

>100_bases
CAGTTCGCCGACGAACTGCGCGTGTCGCTCAGGCGCTGCGGCTGACGAGGCGCGGGCACCGGCGGATATGGCCGGTAGCT
TGCGACGGGGGAGGGTTTGA

Downstream 100 bases:

>100_bases
CGTGTCGCTGAGTTAGTCGACGTATTCGCATTAGGAGATTCTCATGTCTAGCATCGGGCACGACGTAGCCGCGGACCACG
CGCACGACGACCACGCGCAC

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINFQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFVIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GIGFLSTLSTPRDEVMGKKPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVTAQKAKLASAAVDPNKVYTMAELVAHGEEVYKANCAACHQVSGKGL
GAFPAMDGSPIVNGPIAGHVERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDAAGA
AAAAPAEAASAPAQAASGAEQPAAAASAALSTIYFETGKSVLPADAKAAIAAAADYAKAHPDAKLALSGFTDKSGSADAN
AELAKHRAQAVRDALKAAGVAEDHIILKKPETITGGADAKEARRVEIGPAA

Sequences:

>Translated_531_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINFQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFVIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GIGFLSTLSTPRDEVMGKKPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVTAQKAKLASAAVDPNKVYTMAELVAHGEEVYKANCAACHQVSGKGL
GAFPAMDGSPIVNGPIAGHVERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDAAGA
AAAAPAEAASAPAQAASGAEQPAAAASAALSTIYFETGKSVLPADAKAAIAAAADYAKAHPDAKLALSGFTDKSGSADAN
AELAKHRAQAVRDALKAAGVAEDHIILKKPETITGGADAKEARRVEIGPAA
>Mature_531_residues
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINFQPPVTKIAEELYDLHTMMLILCTVIFVGVFGV
MFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFVIVVLMALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGE
GIGFLSTLSTPRDEVMGKKPITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVTAQKAKLASAAVDPNKVYTMAELVAHGEEVYKANCAACHQVSGKGL
GAFPAMDGSPIVNGPIAGHVERVLHGKGAMPSWASLSDLDIASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDAAGA
AAAAPAEAASAPAQAASGAEQPAAAASAALSTIYFETGKSVLPADAKAAIAAAADYAKAHPDAKLALSGFTDKSGSADAN
AELAKHRAQAVRDALKAAGVAEDHIILKKPETITGGADAKEARRVEIGPAA

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=34.3891402714932, Blast_Score=136, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=235, Percent_Identity=32.7659574468085, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 56154; Mature: 56154

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINFQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFVIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGEGIGFLSTLSTPRDEVMGKKP
HCCCCCEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCCCCHHHHCCCCHHHHCCCCC
ITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CCHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVTAQKAKLASAAVDPNKVYTMAELVAH
CHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GEEVYKANCAACHQVSGKGLGAFPAMDGSPIVNGPIAGHVERVLHGKGAMPSWASLSDLD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
IASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDAAGAAAAAPAEAASAPAQAASGAE
HHHHEEECCCCCCCCCHHCCCCHHHHHCCCCCCCCHHCCCCCCCCHHHHCCCHHHHCCCC
QPAAAASAALSTIYFETGKSVLPADAKAAIAAAADYAKAHPDAKLALSGFTDKSGSADAN
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
AELAKHRAQAVRDALKAAGVAEDHIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MEILGKDAMKTIKRALTGVLACSGLLFAGAALAVGDSPGGPRVNEINFQPPVTKIAEELY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHH
DLHTMMLILCTVIFVGVFGVMFYSIFAHRKSKGHKAANFHESTTVEIIWTIVPFVIVVLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALPATKAVVAMKDTTNADLTIKVTGYQWKWGYDYVKGPGEGIGFLSTLSTPRDEVMGKKP
HCCCCCEEEEEECCCCCCEEEEEECEEEECCCCCCCCCCCCCCHHHHCCCCHHHHCCCCC
ITDTYLQEVDNPLVVPVNKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKADKV
CCHHHHHHCCCCEEEECCCCEEEEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
GTFRGFCTELCGKEHAYMPVVVEVLSDDDYAKWVTAQKAKLASAAVDPNKVYTMAELVAH
CHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GEEVYKANCAACHQVSGKGLGAFPAMDGSPIVNGPIAGHVERVLHGKGAMPSWASLSDLD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
IASVITYERNSWGNHKNDLLQPKQVADARNGKMPEDAAGAAAAAPAEAASAPAQAASGAE
HHHHEEECCCCCCCCCHHCCCCHHHHHCCCCCCCCHHCCCCCCCCHHHHCCCHHHHCCCC
QPAAAASAALSTIYFETGKSVLPADAKAAIAAAADYAKAHPDAKLALSGFTDKSGSADAN
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
AELAKHRAQAVRDALKAAGVAEDHIILKKPETITGGADAKEARRVEIGPAA
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]