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The map label for this gene is ctaD [H]

Identifier: 78067644

GI number: 78067644

Start: 3322988

End: 3324595

Strand: Reverse

Name: ctaD [H]

Synonym: Bcep18194_A6175

Alternate gene names: 78067644

Gene position: 3324595-3322988 (Counterclockwise)

Preceding gene: 78067645

Following gene: 78067643

Centisome position: 90.0

GC content: 63.37

Gene sequence:

>1608_bases
ATGTCTAGCATCGGGCACGACGTAGCCGCGGACCACGCGCACGACGACCACGCGCACGAAATGCCGCACGGCTGGCGGCG
CTGGCTGTTCGCCACCAACCACAAGGACATCGGTACGCTGTACCTGTTGTTCTCGTTCATCATGTTCCTGTCGGGCGGCG
TGATGGCGCTCGCCATCCGGGCCGAGCTGTTCGAGCCGGGCCTGCAGATCATGCGTCCGGAGTTCTTCAACGAACTCACG
ACGATGCACGGCCTGATCATGGTGTTCGGCGCGATCATGCCGGCGTTCGTCGGCTTCGCGAACTGGATGATTCCGCTGCA
GATCGGCGCGTCCGACATGGCATTCGCGCGGATGAACAACTTCAGCTTCTGGCTGCTGCCGGTTGCGGCCGTGCTGCTGG
TCGGTTCGTTCTTCGCGCCGGGTGGCGCGACGGCCGCCGGCTGGACGCTCTACGCACCGCTGTCGACGCAGATGGGCCCG
GGCATGGACTTCGCGATCTTCGCGGTCCACATCATGGGCGCATCGTCGATCATGGGCGGGATCAACATCGTCGTGACGAT
CCTGAACATGCGCGCACCGGGCATGACGCTGATGAAGATGCCGATGTTCGCATGGACGTGGCTGATCACGGCGTACCTGC
TGATCGCGGTGATGCCGGTTCTGGCAGGCGCGATCACGATGGTGCTGTTCGACCGCCACTTCGGCACGTCGTTCTTCAAC
GCGGCAGGCGGCGGCGATCCGGTGATGTACCAGCACATCTTCTGGTTCTTCGGCCACCCCGAGGTGTACATCATGATTCT
GCCGGCGTTCGGGATCGTGTCGCAGGTGATCCCGGCGTTCGCACGCAAGACGCTGTTCGGCTATAGCTCGATGGTGTACG
CGACGGCTTCGATCGCAATCCTGTCGTTCATGGTCTGGGCGCACCACATGTTCGCCACGGGCATGCCGGTCACCGGCCAG
CTGTTCTTCATGTACGCGACGATGCTGATCGCGGTGCCGACGGGCGTGAAGGTGTTCAACTGGCTCGCGACGATGTGGCG
CGGCTCGATGACGTTCGAAACCCCGATGCTGTTCGCGATCGGCTTCCTGTTCGTGTTCACGTTCGGCGGTCTCACGGGCC
TGATGCTCGCGATGGCGCCGCTCGACATCCAGTATCACGGTACCTACTTCGTGGTGGCGCACTTCCACTACGTGCTGGTG
GCCGGCTCATTGTTCGCGTTGTTCTCGGGCTGGTACTACTGGGCGCCGAAGTGGACGGGCTGGATGTACAACGAGACGCG
CGGCAAGATCCACTTCTGGGCGTCGATGATCTTCTTCAACCTGACGTTCTTCCCGATGCACTTCGTCGGTCTCGCAGGCA
TGCCGCGTCGCTATGCGGACTACCCGGCGCAGTTCACGGACTTCAACCAGGTGGCGACGATCGGCGCATTCGGCTTCGGC
CTCGCGCAGGTGTACTTCCTGTTCGCGGTCGCGCTGCCGGCCTACCGTGGCGGCGGCGAGCTGGAAAAGGCGTCGGACAA
GCCGTGGGATGGCGCGGAAGGCCTCGAGTGGACGGTGCCGAGCCCGGCTCCCTTCCACACGTTCGAGCAACCGCCGCACG
TCGATTAA

Upstream 100 bases:

>100_bases
ACGGGCGGGGCTGACGCGAAGGAAGCCCGGCGTGTCGAGATCGGCCCGGCGGCTTGACGTGTCGCTGAGTTAGTCGACGT
ATTCGCATTAGGAGATTCTC

Downstream 100 bases:

>100_bases
GTTTCACAGTGCGTTCCGCCGCTGCCTGCCGCGCAGGCAGGCGCGGCGGGCGCCGAATTGAAATTTCAGCGAAGTTTCAG
ATGAACCGGAATCCACAAGA

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSSIGHDVAADHAHDDHAHEMPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVALPAYRGGGELEKASDKPWDGAEGLEWTVPSPAPFHTFEQPPHVD

Sequences:

>Translated_535_residues
MSSIGHDVAADHAHDDHAHEMPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNELT
TMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGP
GMDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQ
LFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLV
AGSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
LAQVYFLFAVALPAYRGGGELEKASDKPWDGAEGLEWTVPSPAPFHTFEQPPHVD
>Mature_534_residues
SSIGHDVAADHAHDDHAHEMPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIRAELFEPGLQIMRPEFFNELTT
MHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNNFSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPG
MDFAIFAVHIMGASSIMGGINIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFNA
AGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAILSFMVWAHHMFATGMPVTGQL
FFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAIGFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVA
GSLFALFSGWYYWAPKWTGWMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFGL
AQVYFLFAVALPAYRGGGELEKASDKPWDGAEGLEWTVPSPAPFHTFEQPPHVD

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=49.119373776908, Blast_Score=457, Evalue=1e-129,
Organism=Escherichia coli, GI1786634, Length=517, Percent_Identity=40.6189555125725, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6226519, Length=529, Percent_Identity=47.4480151228733, Blast_Score=484, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6226524, Length=323, Percent_Identity=50.1547987616099, Blast_Score=328, Evalue=9e-91,
Organism=Saccharomyces cerevisiae, GI6226523, Length=247, Percent_Identity=46.9635627530364, Blast_Score=217, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59566; Mature: 59435

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIGHDVAADHAHDDHAHEMPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIR
CCCCCCCHHCCCCCCCCHHCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHH
AELFEPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWAPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVALPAYRGGGELEKASDKPWDGAEGLEWTVPSPAPFHTFEQPPHVD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSIGHDVAADHAHDDHAHEMPHGWRRWLFATNHKDIGTLYLLFSFIMFLSGGVMALAIR
CCCCCCHHCCCCCCCCHHCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHH
AELFEPGLQIMRPEFFNELTTMHGLIMVFGAIMPAFVGFANWMIPLQIGASDMAFARMNN
HHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCC
FSFWLLPVAAVLLVGSFFAPGGATAAGWTLYAPLSTQMGPGMDFAIFAVHIMGASSIMGG
CCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
INIVVTILNMRAPGMTLMKMPMFAWTWLITAYLLIAVMPVLAGAITMVLFDRHFGTSFFN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
AAGGGDPVMYQHIFWFFGHPEVYIMILPAFGIVSQVIPAFARKTLFGYSSMVYATASIAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFMVWAHHMFATGMPVTGQLFFMYATMLIAVPTGVKVFNWLATMWRGSMTFETPMLFAI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GFLFVFTFGGLTGLMLAMAPLDIQYHGTYFVVAHFHYVLVAGSLFALFSGWYYWAPKWTG
HHHHHHHHHHHHHHHHHHCCCCEEECCCEEEHHHHHHHHHHHHHHHHHCCEEEECCCCCC
WMYNETRGKIHFWASMIFFNLTFFPMHFVGLAGMPRRYADYPAQFTDFNQVATIGAFGFG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHH
LAQVYFLFAVALPAYRGGGELEKASDKPWDGAEGLEWTVPSPAPFHTFEQPPHVD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]