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The map label for this gene is sucC

Identifier: 78067445

GI number: 78067445

Start: 3106046

End: 3107212

Strand: Reverse

Name: sucC

Synonym: Bcep18194_A5976

Alternate gene names: 78067445

Gene position: 3107212-3106046 (Counterclockwise)

Preceding gene: 78067446

Following gene: 78067444

Centisome position: 84.11

GC content: 61.44

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGAGTCGCGGTACCGCGCGGCAAGCCGGCGTTCTC
GGTTGACGAGGCCGTCAAGGTGGCAGAAGAGCTCGGCGGCCCGGTATGGGTCGTGAAGGCTCAGATTCACGCAGGTGGCC
GTGGCAAGGGCGGCGGCGTGAAGGTGGCGAAGTCGATCGAGCAGGTTCGCGAATACGCGAACCAGATCCTCGGCATGCAG
CTCGTCACGCACCAGACCGGTCCGGAAGGCCAGAAGGTCAACCGTCTGATGGTCGAAGAAGGCGCCGACATCAAGCAGGA
ACTGTATGTCAGCCTCGTCGTCGATCGCGTGACGCAAAAGATCGTTCTGATGGGTTCGAGCGAAGGCGGCATGGACATCG
AAGAAGTTGCCGAAAAGCACCCGGAACTGATCCACAAGGTCATCGTCGAGCCGTCGACGGGCCTGCTGGACGCGCAAGCC
GACGACCTCGCCGCGAAGATCGGCGTGCCGGCCGCTTCGATTCCGCAAGCACGCGCAATCCTGCAAGGCCTGTACAAGGC
ATTCTGGGAAACCGACGCATCGCTGGCTGAAATCAACCCGCTGAACGTCTCCAGCGACGGCAAGGTCATCGCACTCGACG
CGAAGTTCAACTTCGACTCGAACGCGCTGTTCCGCCATCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGTCTCGTGAACGGCGCAGG
CCTGGCGATGGCGACGATGGACACCATCAAGCTGTTCGGCGGCGAGCCGGCGAACTTCCTGGACGTCGGCGGTGGCGCGA
CGACCGAGAAGGTCACGGAAGCGTTCAAGCTGATGCTGAAGAACCCGGATCTGAAGGCGATCCTCGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCCGGTTCGAAGGCCGTGAACCTGAACGTGCCGCTCGTCGT
GCGCATGAAGGGCACGAACGAGGACCTCGGCAAAAAGATGCTGGCCGATTCGGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAAGCTGCCCAGAAGGTCGTCGCGGCTGCCGCAGGCAAGTAA

Upstream 100 bases:

>100_bases
ACGTGCCCGGTGAAGGCAGCACGAAGGAATGAACGGAAATCATTCGAAGAAGCGTCTAAAGCGACTTTTCATTCAACTCT
CAGACTGAAGGGAATCACGC

Downstream 100 bases:

>100_bases
GCGCGCTATTGAACACGCTGGCGGCGCGGTTTGCACGCGACGCCAATCGAACAGAGGTCAAAATACATGTCGATTCTGAT
CAACAAGGACACGAAGGTCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMVEEGADIKQELYVSLVVDRVTQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSSDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMVEEGADIKQELYVSLVVDRVTQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSSDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQ
LVTHQTGPEGQKVNRLMVEEGADIKQELYVSLVVDRVTQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQA
DDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSSDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=48.3290488431877, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.7362924281984, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.7966573816156, Blast_Score=315, Evalue=6e-86,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.8350515463918, Blast_Score=403, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.0381679389313, Blast_Score=339, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.6153846153846, Blast_Score=330, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=45.4081632653061, Blast_Score=352, Evalue=8e-98,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.8979591836735, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.6428571428571, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.6428571428571, Blast_Score=321, Evalue=6e-88,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.7837150127226, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.7837150127226, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_BURS3 (Q39D96)

Other databases:

- EMBL:   CP000151
- RefSeq:   YP_370214.1
- HSSP:   P53590
- ProteinModelPortal:   Q39D96
- SMR:   Q39D96
- STRING:   Q39D96
- GeneID:   3751207
- GenomeReviews:   CP000151_GR
- KEGG:   bur:Bcep18194_A5976
- NMPDR:   fig|269483.3.peg.7457
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   KKELYVS
- ProtClustDB:   PRK00696
- BioCyc:   BSP36773:BCEP18194_A5976-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41282; Mature: 41282

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3; PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMVEEGADIKQELYVSLVVDRVTQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSSDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMVEEGADIKQELYVSLVVDRVTQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSSDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA