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The map label for this gene is sucD [H]

Identifier: 78067444

GI number: 78067444

Start: 3105098

End: 3105979

Strand: Reverse

Name: sucD [H]

Synonym: Bcep18194_A5975

Alternate gene names: 78067444

Gene position: 3105979-3105098 (Counterclockwise)

Preceding gene: 78067445

Following gene: 78067443

Centisome position: 84.08

GC content: 62.59

Gene sequence:

>882_bases
ATGTCGATTCTGATCAACAAGGACACGAAGGTCATCACGCAGGGCATTACCGGCAAAACCGGTCAGTTCCATACGCGCGC
CTGCCGTGAATACGCAAACGGCCGCGAAGCATTCGTCGCGGGCGTGAACCCGAAGAAGGCCGGCGAAGATTTCGAAGGCA
TTCCGATCTACGCAAGCGTCAAGGAAGCGAAGGCAGAAACCGGCGCGACCGTGTCGGTCATCTACGTTCCGCCGGCAGGC
GCAGCAGCTGCGATCTGGGAAGCGGTCGAAGCCGATCTGGATCTCGCGATCTGTATCACGGAAGGCATCCCCGTCCGCGA
CATGATCGAAGTGAAGGACCGCATGCGTCGCGAAGGCCGCAAGACGCTGCTGCTCGGGCCGAACTGCCCGGGCACGATCA
CGCCGGACGAACTGAAGATCGGCATCATGCCGGGCCACATCCACCGCAAGGGCCGCATCGGCGTCGTGTCGCGTTCGGGC
ACGCTGACGTATGAAGCGGTTGCCCAGCTGACGGCACTCGGCCTCGGCCAGTCGTCGGCAGTCGGTATCGGCGGCGACCC
GATCAACGGTCTGAAGCACATCGACGTGATGAAGATGTTCAACGACGATCCGGATACGGACGCAGTCGTGATGATCGGCG
AAATCGGCGGTCCGGACGAAGCCAATGCGGCAGAGTGGATCAAGGACAACATGAAGAAGCCGGTCGTCGGCTTCATCGCT
GGCGTCACGGCGCCTCCGGGCAAGCGCATGGGCCACGCCGGCGCGCTGATCTCGGGCGGTGCGGATACGGCCGAAGCGAA
GCTGGAAATCATGGAAGCGTGCGGCATCACCGTCACGCGCAACCCGTCGGAAATGGGCCGTCTGCTGAAGAAGGCGCTGT
AA

Upstream 100 bases:

>100_bases
CCAGAAGGTCGTCGCGGCTGCCGCAGGCAAGTAAGCGCGCTATTGAACACGCTGGCGGCGCGGTTTGCACGCGACGCCAA
TCGAACAGAGGTCAAAATAC

Downstream 100 bases:

>100_bases
TATTTCCCCTGGGTTCGTCCTGCAGAAAACGCCGGCTTTGCCGGCGTTTTTTGTTATGCTCGCGCAATGAATTCGTAAGC
ACCGGGCATGCATCGCGCAT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAEWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKKAL

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAEWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKKAL
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAGA
AAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAEWIKDNMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKKAL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=54.5762711864407, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI38569423, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI38569421, Length=207, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=54.9488054607508, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.1081081081081, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=296, Percent_Identity=53.3783783783784, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17553126, Length=296, Percent_Identity=54.0540540540541, Blast_Score=300, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17557344, Length=313, Percent_Identity=26.517571884984, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=26.2745098039216, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=47.972972972973, Blast_Score=265, Evalue=7e-72,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=49.6575342465753, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI28574296, Length=296, Percent_Identity=53.3783783783784, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI281363477, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363475, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363473, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30824; Mature: 30693

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAEWIKDNMKKPVVGFIA
ECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKKAL
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAEWIKDNMKKPVVGFIA
ECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKKAL
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]