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The map label for this gene is pcaK [H]

Identifier: 78067380

GI number: 78067380

Start: 3031353

End: 3032816

Strand: Reverse

Name: pcaK [H]

Synonym: Bcep18194_A5911

Alternate gene names: 78067380

Gene position: 3032816-3031353 (Counterclockwise)

Preceding gene: 78067381

Following gene: 78067376

Centisome position: 82.1

GC content: 72.13

Gene sequence:

>1464_bases
ATGCCGTTGTCTTGCCGCGCGCCGCGCGCGCACGTTGCCGCCTGGGCGCGGTACACGGGAGGTCGCATGAGCACGCGCGA
CGGATTGCAGCCTCCGTCCGTCGACATCGGCGCGACGCTCGACGACGGGCCGTTCACGACGATGCAGCGCTGCGTGGTGC
TGCTCGCCGCGCTCGCGATCGTGCTCGACGGCTTCGACGGCCAGCTGATCGGCTTCGCGATTCCGGTGCTGATCCGCGAA
TGGGGCATCACGCGTGGCGCGTTCGCGCCGGCGGTGGCGGCCGGGCTGATCGGGATGGGCATCGGCAGCGCGTGCGCGGG
GATCGTCGCGGACCGCTTCGGCCGCCGCCAGGCCGTGATCGGCAGCGTGTTCCTGTTCGGCATTGCGACCTGCGCGATCG
GCTTCGCACCGGACGTCACGGCGATCGCGGCGCTGCGCTTCGTCGCAGGCCTCGGGATCGGCGGCGCGTTGCCGACGGCC
ACGACGATGACGGCCGAATACACGCCCGCGCGGCGTCGCACGATGATGGTGACCGCGACGATCGTCTGCGTGCCGCTCGG
CGGGATGCTGGCCGGCCTGTTCGCGCACGAGGTGCTGCCGCGCTACGGCTGGCGCGGGCTGTTCTTCGCGGGCGGCGCAT
TGCCGCTCGTGCTCGGCTTCGTGCTCGTGCGTGCGCTGCCCGAATCGCCGCGCTATCTTGCGCGGCGCCCCGCGCGCTGG
CCGGAACTCGGCGCGCTGCTCGCGCGGATGGAGCGGCCCGTCGCGCCGGGCACTGCCTTCACCGACATGCGGGACGCGCG
CGCGGCGGGCGGCCGTGGCGGCTTCGGCGCGTTGTTCGAGAGCGGTCAGGCGCGCGACACGATCGCGCTGTGGTGCGCGT
TCTTCATGTGCCTGCTCGCCGTGTATGCGGCGTTCAGCTGGCTGCCGACGATGCTGGCGGCGAGCGGGCTGAGCGTGTCG
GTCGCGGGGACGGGGCTCACCGCATACAACCTCGGTGGCGTGATCGGTGCGCTGTTGTGCGCGTGGACGATCGCGCATGC
CGGGTCGCGCTGGCCGCTCGTGTTGTGCAGCATCGGCGGCGCGGCGAGTGCGGTATGGCTGATGGGTGTCGATGCGAGCC
GCCACACGGGCTGGCTGATCGTCGGGCTCGGCCTGCACGGGCTGTTCGTCAACGCGGTGCAGTCGACGATGTATGCGCTC
TGCGCGTACATCTACCCGACGGCCGTGCGCGCGACGGGCACGGCAAGCGCGCTCGCGTTCGGCCGGCTCGGCGCGATCCT
CAGCGCGTTCGCGGGCGCGATCGTGATCACCACGGGCGGTGCCACGGCTTATCTGACGATGCTGGCGATTGCGATGGGGG
TGGTCTGCGTCGCGCTGCTCGTCGTGCGACGGCACATTCCGCGACTGTCGCGCGCGGCGGTGCAGCCGCGCGAAGGGGAG
GAACTGGCCCGCACGTCGTCGTGA

Upstream 100 bases:

>100_bases
TGCGTCGACACCGGCCGACTGCGCAGCACGAGATCCGGGCACGCGCCACCGCGCCAGCCCGGGCAACCGGAGACGCCATG
AACGCCATGAACGCCATCGA

Downstream 100 bases:

>100_bases
CGGCGGGCAGGCCAGGGGGCGCGTCGCGCGTTACAGCGTGGTGCGCACGTGCCAGAGCTCGGGGAACAGCACGACGTCGA
GCATCTTGCGCAGGTACGGC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MPLSCRAPRAHVAAWARYTGGRMSTRDGLQPPSVDIGATLDDGPFTTMQRCVVLLAALAIVLDGFDGQLIGFAIPVLIRE
WGITRGAFAPAVAAGLIGMGIGSACAGIVADRFGRRQAVIGSVFLFGIATCAIGFAPDVTAIAALRFVAGLGIGGALPTA
TTMTAEYTPARRRTMMVTATIVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPESPRYLARRPARW
PELGALLARMERPVAPGTAFTDMRDARAAGGRGGFGALFESGQARDTIALWCAFFMCLLAVYAAFSWLPTMLAASGLSVS
VAGTGLTAYNLGGVIGALLCAWTIAHAGSRWPLVLCSIGGAASAVWLMGVDASRHTGWLIVGLGLHGLFVNAVQSTMYAL
CAYIYPTAVRATGTASALAFGRLGAILSAFAGAIVITTGGATAYLTMLAIAMGVVCVALLVVRRHIPRLSRAAVQPREGE
ELARTSS

Sequences:

>Translated_487_residues
MPLSCRAPRAHVAAWARYTGGRMSTRDGLQPPSVDIGATLDDGPFTTMQRCVVLLAALAIVLDGFDGQLIGFAIPVLIRE
WGITRGAFAPAVAAGLIGMGIGSACAGIVADRFGRRQAVIGSVFLFGIATCAIGFAPDVTAIAALRFVAGLGIGGALPTA
TTMTAEYTPARRRTMMVTATIVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPESPRYLARRPARW
PELGALLARMERPVAPGTAFTDMRDARAAGGRGGFGALFESGQARDTIALWCAFFMCLLAVYAAFSWLPTMLAASGLSVS
VAGTGLTAYNLGGVIGALLCAWTIAHAGSRWPLVLCSIGGAASAVWLMGVDASRHTGWLIVGLGLHGLFVNAVQSTMYAL
CAYIYPTAVRATGTASALAFGRLGAILSAFAGAIVITTGGATAYLTMLAIAMGVVCVALLVVRRHIPRLSRAAVQPREGE
ELARTSS
>Mature_486_residues
PLSCRAPRAHVAAWARYTGGRMSTRDGLQPPSVDIGATLDDGPFTTMQRCVVLLAALAIVLDGFDGQLIGFAIPVLIREW
GITRGAFAPAVAAGLIGMGIGSACAGIVADRFGRRQAVIGSVFLFGIATCAIGFAPDVTAIAALRFVAGLGIGGALPTAT
TMTAEYTPARRRTMMVTATIVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPESPRYLARRPARWP
ELGALLARMERPVAPGTAFTDMRDARAAGGRGGFGALFESGQARDTIALWCAFFMCLLAVYAAFSWLPTMLAASGLSVSV
AGTGLTAYNLGGVIGALLCAWTIAHAGSRWPLVLCSIGGAASAVWLMGVDASRHTGWLIVGLGLHGLFVNAVQSTMYALC
AYIYPTAVRATGTASALAFGRLGAILSAFAGAIVITTGGATAYLTMLAIAMGVVCVALLVVRRHIPRLSRAAVQPREGEE
LARTSS

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=440, Percent_Identity=24.5454545454545, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI166064021, Length=424, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI213021148, Length=414, Percent_Identity=23.6714975845411, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI87081723, Length=334, Percent_Identity=31.1377245508982, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1786229, Length=453, Percent_Identity=23.6203090507726, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788068, Length=443, Percent_Identity=23.7020316027088, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082231, Length=202, Percent_Identity=31.1881188118812, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082159, Length=393, Percent_Identity=27.2264631043257, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082404, Length=205, Percent_Identity=25.8536585365854, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788074, Length=368, Percent_Identity=24.7282608695652, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789152, Length=407, Percent_Identity=22.8501228501229, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789207, Length=189, Percent_Identity=30.6878306878307, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790463, Length=257, Percent_Identity=27.2373540856031, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=428, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19922874, Length=426, Percent_Identity=23.943661971831, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649622, Length=383, Percent_Identity=24.8041775456919, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50532; Mature: 50401

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSCRAPRAHVAAWARYTGGRMSTRDGLQPPSVDIGATLDDGPFTTMQRCVVLLAALAI
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLDGFDGQLIGFAIPVLIREWGITRGAFAPAVAAGLIGMGIGSACAGIVADRFGRRQAVI
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
GSVFLFGIATCAIGFAPDVTAIAALRFVAGLGIGGALPTATTMTAEYTPARRRTMMVTAT
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHEEHEEHH
IVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPESPRYLARRPARW
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHCCCCC
PELGALLARMERPVAPGTAFTDMRDARAAGGRGGFGALFESGQARDTIALWCAFFMCLLA
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHH
VYAAFSWLPTMLAASGLSVSVAGTGLTAYNLGGVIGALLCAWTIAHAGSRWPLVLCSIGG
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
AASAVWLMGVDASRHTGWLIVGLGLHGLFVNAVQSTMYALCAYIYPTAVRATGTASALAF
HHHEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GRLGAILSAFAGAIVITTGGATAYLTMLAIAMGVVCVALLVVRRHIPRLSRAAVQPREGE
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCH
ELARTSS
HHHCCCC
>Mature Secondary Structure 
PLSCRAPRAHVAAWARYTGGRMSTRDGLQPPSVDIGATLDDGPFTTMQRCVVLLAALAI
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLDGFDGQLIGFAIPVLIREWGITRGAFAPAVAAGLIGMGIGSACAGIVADRFGRRQAVI
HHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
GSVFLFGIATCAIGFAPDVTAIAALRFVAGLGIGGALPTATTMTAEYTPARRRTMMVTAT
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHEEHEEHH
IVCVPLGGMLAGLFAHEVLPRYGWRGLFFAGGALPLVLGFVLVRALPESPRYLARRPARW
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHCCCCC
PELGALLARMERPVAPGTAFTDMRDARAAGGRGGFGALFESGQARDTIALWCAFFMCLLA
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHH
VYAAFSWLPTMLAASGLSVSVAGTGLTAYNLGGVIGALLCAWTIAHAGSRWPLVLCSIGG
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
AASAVWLMGVDASRHTGWLIVGLGLHGLFVNAVQSTMYALCAYIYPTAVRATGTASALAF
HHHEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GRLGAILSAFAGAIVITTGGATAYLTMLAIAMGVVCVALLVVRRHIPRLSRAAVQPREGE
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCH
ELARTSS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]