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The map label for this gene is fabG2 [H]

Identifier: 78067349

GI number: 78067349

Start: 3001006

End: 3001764

Strand: Direct

Name: fabG2 [H]

Synonym: Bcep18194_A5880

Alternate gene names: 78067349

Gene position: 3001006-3001764 (Clockwise)

Preceding gene: 78067348

Following gene: 78067352

Centisome position: 81.24

GC content: 71.67

Gene sequence:

>759_bases
ATGGAAATTCGCGGCAACGTGTTTCTGATCACGGGCGGCGCATCGGGCCTCGGCGCCGGCACCGCGCGGATGCTCGCGCA
GGCAGGCGGCACGGTCGTGCTCGCCGACCTGAACGACGCGGCGGGCACCGCGCTCGCAGCCGAGCTGGGCGGCATCTTCG
TGCACTGCGACGTGTCGAGCGAGGCCGACGCGCAGGCGGCCGTCAACGCGGCGACGCGCGCCGGCACGCTGCGCGGCCTC
GTGAACTGCGCGGGCATCGCGCCCGCCGCGAAGACCGTCGGCAAGGACGGCGCGCATCCGCTCGACGTGTTCGCGAAGAC
GATCAACGTGAACCTCGTCGGCACGTTCAACATGATCCGGCTCGCGGCCGCCGCGATGGCCGCCACCGCGCCGACCGCGG
ACGGCGAGCGCGGCGTGATCGTCAGCACCGCGTCGGTCGCCGCCTTCGACGGGCAGATCGGCCAGGCCGCGTATGCGGCG
TCGAAAGCCGGCGTCGCGGGTATGACGCTGCCGATCGCGCGCGACCTGTCGCGCAGCGGCATCCGCGTGATGACGATCGC
GCCCGGCCTGTTCGAGACGCCGATGCTGCTCGGCATGCCGCAGGACGTGCAGGACGCGCTCGGCGCGATGGTGCCGTTCC
CGCCGCGACTCGGCAAGCCGGCCGAATACGCGCTGCTGGTGCGCCAGATCGTCGAGAATCCGATGCTCAACGGCGAAGTG
ATCCGCCTCGACGGCGCAATCCGGATGCAGCCGAAATAG

Upstream 100 bases:

>100_bases
GACCTCCCTAAGCGCTAAAGCGCCAAGGGCGGTCGACCGCCTTGGCATGGGACCGCCCTAAGCGCTGAAGCGCCAAGGGC
GGTCGACAAAGGAGACAGTC

Downstream 100 bases:

>100_bases
GCATAAAAAACGCCCGCGATGCGGGCGTTTTTTCGTTCCGGGTTCCGGCAGCGTGGCCGCGGCTCAGTCCTCGCCGTCGC
GCTGCATCCGCTGCCGCAAT

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEIRGNVFLITGGASGLGAGTARMLAQAGGTVVLADLNDAAGTALAAELGGIFVHCDVSSEADAQAAVNAATRAGTLRGL
VNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIRLAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAA
SKAGVAGMTLPIARDLSRSGIRVMTIAPGLFETPMLLGMPQDVQDALGAMVPFPPRLGKPAEYALLVRQIVENPMLNGEV
IRLDGAIRMQPK

Sequences:

>Translated_252_residues
MEIRGNVFLITGGASGLGAGTARMLAQAGGTVVLADLNDAAGTALAAELGGIFVHCDVSSEADAQAAVNAATRAGTLRGL
VNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIRLAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAA
SKAGVAGMTLPIARDLSRSGIRVMTIAPGLFETPMLLGMPQDVQDALGAMVPFPPRLGKPAEYALLVRQIVENPMLNGEV
IRLDGAIRMQPK
>Mature_252_residues
MEIRGNVFLITGGASGLGAGTARMLAQAGGTVVLADLNDAAGTALAAELGGIFVHCDVSSEADAQAAVNAATRAGTLRGL
VNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIRLAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAA
SKAGVAGMTLPIARDLSRSGIRVMTIAPGLFETPMLLGMPQDVQDALGAMVPFPPRLGKPAEYALLVRQIVENPMLNGEV
IRLDGAIRMQPK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=57.4803149606299, Blast_Score=268, Evalue=3e-72,
Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=54.5098039215686, Blast_Score=244, Evalue=5e-65,
Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=35.2697095435685, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=30.1204819277108, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI59889578, Length=215, Percent_Identity=30.2325581395349, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87082100, Length=239, Percent_Identity=31.3807531380753, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=30.5882352941176, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082160, Length=204, Percent_Identity=30.3921568627451, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=235, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367175, Length=195, Percent_Identity=32.8205128205128, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=51.004016064257, Blast_Score=241, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17555706, Length=223, Percent_Identity=35.4260089686099, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=224, Percent_Identity=33.0357142857143, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=215, Percent_Identity=26.9767441860465, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=27.5471698113208, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=206, Percent_Identity=30.0970873786408, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=59.8425196850394, Blast_Score=287, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=33.59375, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=231, Percent_Identity=31.1688311688312, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571526, Length=234, Percent_Identity=29.4871794871795, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644339, Length=231, Percent_Identity=29.4372294372294, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=200, Percent_Identity=31, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25432; Mature: 25432

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRGNVFLITGGASGLGAGTARMLAQAGGTVVLADLNDAAGTALAAELGGIFVHCDVSS
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCEEEEEECCC
EADAQAAVNAATRAGTLRGLVNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHEEEEEEEEEEEHHHHHH
LAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAASKAGVAGMTLPIARDLSRSG
HHHHHHHHCCCCCCCCCCEEEEECEEEEECCCCCHHHHHHHCCCCCCEEEHHHHHHHHCC
IRVMTIAPGLFETPMLLGMPQDVQDALGAMVPFPPRLGKPAEYALLVRQIVENPMLNGEV
EEEEEECCCHHHCCHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
IRLDGAIRMQPK
EEECCEEEECCC
>Mature Secondary Structure
MEIRGNVFLITGGASGLGAGTARMLAQAGGTVVLADLNDAAGTALAAELGGIFVHCDVSS
CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCEEEEEECCC
EADAQAAVNAATRAGTLRGLVNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHEEEEEEEEEEEHHHHHH
LAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAASKAGVAGMTLPIARDLSRSG
HHHHHHHHCCCCCCCCCCEEEEECEEEEECCCCCHHHHHHHCCCCCCEEEHHHHHHHHCC
IRVMTIAPGLFETPMLLGMPQDVQDALGAMVPFPPRLGKPAEYALLVRQIVENPMLNGEV
EEEEEECCCHHHCCHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
IRLDGAIRMQPK
EEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]