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The map label for this gene is kdsB1 [H]

Identifier: 78067347

GI number: 78067347

Start: 2999004

End: 2999789

Strand: Direct

Name: kdsB1 [H]

Synonym: Bcep18194_A5878

Alternate gene names: 78067347

Gene position: 2999004-2999789 (Clockwise)

Preceding gene: 78067346

Following gene: 78067348

Centisome position: 81.18

GC content: 69.97

Gene sequence:

>786_bases
ATGACTCAACCCTTCATCGCCGTCATTCCCGCCCGGCTCGCGTCGACGCGACTCCCGAACAAGCCGCTCGCCGATCTCGG
CGGCAAGCCGATGGTCGTGCGCGTCGCCGAACGCGCGCGCGAAGCGGGCGCGCAGCAGGTGCTGGTCGCGTCCGACGCGC
AGAGCGTGCTCGATGCGGCCCGCGATCACGGCTTCGAAGCGGTGCTGACGCGCGCCGACCATCCGTCCGGCACCGACCGG
CTCGCGGAAGTCGCGGCGACGCTCGGGTGGAGCGACGACACCGTCGTCGTCAACGTGCAGGGCGACGAGCCGCTGATCGA
CCCCGTGCTCGTACGCGACGTAGCGTCGCACCTCGCCGCCCACCCGGCCTGCGCGATTGCGACGGCCGCCCACCCGATCC
ACGACGCCGCCGACGTGTTCAACCCGAACGTGGTGAAGGTCGCGCTCGACGCGCAGAGCGTCGCGCTGTACTTCTCGCGT
GCGCCGATTCCGTGGAGCCGGGACGCATACCAGCCGCACTGGCCCGACGTCGCGGCCATGCCTGCGCCCGCTTTCCCGGT
CTACCGGCACATCGGCCTCTATGCGTATCGCGCGCGTTTCCTGCGCACGTATCCGACGCTCGCGCAGGCGCCGATCGAAC
AGGCCGAGCAGCTCGAACAGCTGCGCGCGCTGTGGCACGGCGAGCGCATCGCAGTGCTGATCACCGAGTCCGCGCCCGAA
GCCGGAATCGACACGCCGGCCGATCTCGCACGCGTGCAGGCCCTTTTTCAGCCGTCATCAAAATAA

Upstream 100 bases:

>100_bases
CGGCCCTCGCCGCGGCCCGTCCGCCGCGAGGGCGCCGAACCCCGCCGGGCGGCCCGCACCAGACGCGCCGCCCGCTCCGC
TCTTCTCACCGCCCTCCCCG

Downstream 100 bases:

>100_bases
CCCGTGGCATAATCAGGCGATTGTGCGAGCCGTCCGCGACCAGCGCGTCCTCGCTTGACCCCGCCCGCGGCCCTGCCGGC
AGCCGCGCGTCGCTCAACCC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase 1; CKS 1; CMP-KDO synthase 1 [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGTDR
LAEVAATLGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSR
APIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPTLAQAPIEQAEQLEQLRALWHGERIAVLITESAPE
AGIDTPADLARVQALFQPSSK

Sequences:

>Translated_261_residues
MTQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGTDR
LAEVAATLGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSR
APIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPTLAQAPIEQAEQLEQLRALWHGERIAVLITESAPE
AGIDTPADLARVQALFQPSSK
>Mature_260_residues
TQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGTDRL
AEVAATLGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSRA
PIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPTLAQAPIEQAEQLEQLRALWHGERIAVLITESAPEA
GIDTPADLARVQALFQPSSK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=250, Percent_Identity=52.4, Blast_Score=261, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28140; Mature: 28009

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAA
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEEHHHHHHHHHHH
RDHGFEAVLTRADHPSGTDRLAEVAATLGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAA
HHCCHHEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
HPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSRAPIPWSRDAYQPHWPDVAAM
CCHHHHHHHCCCCHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
PAPAFPVYRHIGLYAYRARFLRTYPTLAQAPIEQAEQLEQLRALWHGERIAVLITESAPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
AGIDTPADLARVQALFQPSSK
CCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAA
CCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEHHHHHHHHHCCHHEEEEHHHHHHHHHHH
RDHGFEAVLTRADHPSGTDRLAEVAATLGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAA
HHCCHHEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
HPACAIATAAHPIHDAADVFNPNVVKVALDAQSVALYFSRAPIPWSRDAYQPHWPDVAAM
CCHHHHHHHCCCCHHHHHHCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCC
PAPAFPVYRHIGLYAYRARFLRTYPTLAQAPIEQAEQLEQLRALWHGERIAVLITESAPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
AGIDTPADLARVQALFQPSSK
CCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA