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The map label for this gene is ytnA [H]

Identifier: 78067318

GI number: 78067318

Start: 2964572

End: 2965978

Strand: Reverse

Name: ytnA [H]

Synonym: Bcep18194_A5849

Alternate gene names: 78067318

Gene position: 2965978-2964572 (Counterclockwise)

Preceding gene: 78067319

Following gene: 78067317

Centisome position: 80.29

GC content: 67.02

Gene sequence:

>1407_bases
ATGGTGGTGCAGGGGAGTGGCAACGCAGTGACACAACAACAACGGTCGTTCGACGACATCGTCGCGCGCGAACAGGGTTT
GCGCCATGCGCTGACGTCTGGGCAGATGGCGATGATCGCGATCGGCGGCGCGATCGGCACGGGGCTGTTCCTCGGCAGCG
GGTTCGCGATCGGGCTCGCCGGCCCGAGCGTGCTGGTTTCTTACGCGATCGGCGCGTTGATCGCGCTGCTGCTGATGGGC
GCGCTGGCGGAAATGACGGTCGCGCATCCGACGGCCGGCTCGTTCGGCGCGTATGCCGAGCACTATGTCGGCCCGCTGGC
GGGCTTCCTGGTGCGCTATGCGTACTGGTTCGCGGTCGTGTTCGCGATCGGCACCGAGATCAGCGCGATCGCCGTGTTCA
TGAAGTACTGGTTCCCGGCCGTGCCCGGCTGGTACTGGGTGATCGGCTTCTCCGCGCTGCTGATCGCCGTGAATCTCGCG
AGCGTCACGCTGTACGGCACAGTCGAATACGCGTTCTCGCTGCTGAAGATTGCGGCGATCGTCGTGTTCATCGTGCTCGG
CGCATACCTCGTGTGGTCGGCGCCGGCCGCATCGGGCGTCGGTTTCGCGAACTACACCGCGCACGGCGGCTTCATGCCGA
AGGGGCCGTGGGGCACCTGGGTCGCGGTGATCGTCGCGATCTTCAGTTACATGAGCATCGAAGCCGTCGCGATCGCGGCC
GGCGAGGCGCGCGATCCGCAGCACGCGGTCACGCGCGCGTTCCGCTCGACCGTGTTCCGGCTCGTGCTGTTCTACCTGCT
GACGCTGTCGCTGATGCTCGCGATCGTGCCGTGGACGCAGGCCGGTACCGACGAAAGCCCGTTCGTGAAGGTCATGGCCG
CGACCCACGTGCCTTACGCGGCAGGCGTGATCAACTTCGTGTTGCTGATCGCGGCGCTGTCGGCGATGAACAGCCAGCTT
TACGTGACGACGCGGATGATGTTCAGCCTGTCGCGCGCACGGCTCGCGCCCGCGGTGTTCGGCCGGCTCGGCACGAACGG
CGTGCCGCGCGCGGCGCTGTGGATCTCGACGAGCGGTGTCGCGGTGGCGGCCGTGCTGGTCGCGCTCGCGCCCGACACCG
CGTTCACCGTGATGATGGCGATCGCGATGTTCGGTGCACTGTTCACGTGGCTGATGATCTTCGTCACGCACCTGCGCTTC
CGTTCGCGGTATCGCGGCCCCGCGCTCGCGTTCCGGATGTGGGGACACCCGTTCGGCAGCCTGCTCGGTGCGGGACTCGT
CGCGGCGATCCTGTTCACGACCGCGTTCACGCGGGAATTCCGGATGACGATGGTGGTCGGCGTCGTGTTCGCCGTGCTGC
TCACGCTCGCGTACGCGCTGCATTACCGGCACCAGCACGCGCGTTGA

Upstream 100 bases:

>100_bases
GAAGAGGCGGTCGAAGTCGAATAAGCGATAATTCGTTGTTCATGCGAACGGCGCGGGAAGTTCTCCGCGCCGTTTCGTTT
TATCTGGCGCCGGCGGCGCG

Downstream 100 bases:

>100_bases
TGGCCACGGCGCGGCCTGCCCCGCCTACGCCGCTTCCCCGTCGCTAAGGTTCCGTTAAGCCCGCGGCGACTACATTCGAT
CCTGTCTGCAAGGCAGGCCG

Product: amino acid tranporter

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MVVQGSGNAVTQQQRSFDDIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWSAPAASGVGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGTNGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RSRYRGPALAFRMWGHPFGSLLGAGLVAAILFTTAFTREFRMTMVVGVVFAVLLTLAYALHYRHQHAR

Sequences:

>Translated_468_residues
MVVQGSGNAVTQQQRSFDDIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWSAPAASGVGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGTNGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RSRYRGPALAFRMWGHPFGSLLGAGLVAAILFTTAFTREFRMTMVVGVVFAVLLTLAYALHYRHQHAR
>Mature_468_residues
MVVQGSGNAVTQQQRSFDDIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLAGPSVLVSYAIGALIALLLMG
ALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVVFAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLA
SVTLYGTVEYAFSLLKIAAIVVFIVLGAYLVWSAPAASGVGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
GEARDPQHAVTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYAAGVINFVLLIAALSAMNSQL
YVTTRMMFSLSRARLAPAVFGRLGTNGVPRAALWISTSGVAVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRF
RSRYRGPALAFRMWGHPFGSLLGAGLVAAILFTTAFTREFRMTMVVGVVFAVLLTLAYALHYRHQHAR

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786789, Length=451, Percent_Identity=36.8070953436807, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI87081708, Length=448, Percent_Identity=36.6071428571429, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1786602, Length=448, Percent_Identity=33.9285714285714, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1786302, Length=445, Percent_Identity=32.1348314606742, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1790653, Length=419, Percent_Identity=34.1288782816229, Blast_Score=254, Evalue=9e-69,
Organism=Escherichia coli, GI48994972, Length=458, Percent_Identity=33.1877729257642, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=33.743842364532, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1789017, Length=419, Percent_Identity=33.890214797136, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1788480, Length=394, Percent_Identity=35.0253807106599, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87081869, Length=246, Percent_Identity=28.0487804878049, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320772, Length=415, Percent_Identity=30.1204819277108, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324061, Length=456, Percent_Identity=29.8245614035088, Blast_Score=182, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6324553, Length=445, Percent_Identity=30.3370786516854, Blast_Score=176, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6324059, Length=505, Percent_Identity=30.6930693069307, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324924, Length=430, Percent_Identity=28.1395348837209, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324990, Length=419, Percent_Identity=29.8329355608592, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322892, Length=437, Percent_Identity=29.9771167048055, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6321629, Length=418, Percent_Identity=25.5980861244019, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=429, Percent_Identity=28.4382284382284, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=403, Percent_Identity=25.8064516129032, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=409, Percent_Identity=26.4058679706601, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319543, Length=394, Percent_Identity=27.6649746192893, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6319542, Length=420, Percent_Identity=25.7142857142857, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6321053, Length=396, Percent_Identity=26.2626262626263, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322967, Length=437, Percent_Identity=25.4004576659039, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319608, Length=466, Percent_Identity=24.4635193133047, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324981, Length=442, Percent_Identity=27.1493212669683, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320364, Length=495, Percent_Identity=22.6262626262626, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50047; Mature: 50047

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVQGSGNAVTQQQRSFDDIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECC
GPSVLVSYAIGALIALLLMGALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGTVEYAFSLLKIAAI
HHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFIVLGAYLVWSAPAASGVGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GEARDPQHAVTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
AGVINFVLLIAALSAMNSQLYVTTRMMFSLSRARLAPAVFGRLGTNGVPRAALWISTSGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
AVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRSRYRGPALAFRMWGHPFGS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
LLGAGLVAAILFTTAFTREFRMTMVVGVVFAVLLTLAYALHYRHQHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVQGSGNAVTQQQRSFDDIVAREQGLRHALTSGQMAMIAIGGAIGTGLFLGSGFAIGLA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCEEECC
GPSVLVSYAIGALIALLLMGALAEMTVAHPTAGSFGAYAEHYVGPLAGFLVRYAYWFAVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FAIGTEISAIAVFMKYWFPAVPGWYWVIGFSALLIAVNLASVTLYGTVEYAFSLLKIAAI
HHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVFIVLGAYLVWSAPAASGVGFANYTAHGGFMPKGPWGTWVAVIVAIFSYMSIEAVAIAA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GEARDPQHAVTRAFRSTVFRLVLFYLLTLSLMLAIVPWTQAGTDESPFVKVMAATHVPYA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHH
AGVINFVLLIAALSAMNSQLYVTTRMMFSLSRARLAPAVFGRLGTNGVPRAALWISTSGV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHH
AVAAVLVALAPDTAFTVMMAIAMFGALFTWLMIFVTHLRFRSRYRGPALAFRMWGHPFGS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHH
LLGAGLVAAILFTTAFTREFRMTMVVGVVFAVLLTLAYALHYRHQHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]