Click here to switch to the map view.

The map label for this gene is lspA

Identifier: 78067314

GI number: 78067314

Start: 2961329

End: 2961829

Strand: Direct

Name: lspA

Synonym: Bcep18194_A5845

Alternate gene names: 78067314

Gene position: 2961329-2961829 (Clockwise)

Preceding gene: 78067313

Following gene: 78067315

Centisome position: 80.16

GC content: 65.07

Gene sequence:

>501_bases
ATGGCGAAAACCCTGTCGAAACCGGCCAGCGGCGCGCTTGCGCCCTGGCTCGGCATTTCGCTGATCGTGATCCTGTTCGA
CCAGCTGTCGAAGATCGCGATCCTGAAAACGTTCGTGTATGGCGCGCAGCACGAGCTGACGTCGTTCTTCAACCTCGTGC
TGGTGTACAACCGCGGCGCCGCGTTCGGCTTCCTGTCGACCGCAGGCGGCTGGCAGCGCTGGGCGTTCACCGCGCTCGGC
ATCGCCGCGACGCTCGTGATCTGCTTCCTGCTGAAGCGTCACGGCCAGCAGCGGCTGTTCAGCCTGTCGCTCGCCATGAT
CCTCGGCGGCGCACTCGGCAACGTGATCGACCGGCTCGTCTACGGCCACGTGATCGACTTCCTCGATTTCCATCTCGGCG
CCTGGCACTTCCCGGCGTTCAACCTCGCCGATTCCGCGATCACGGTCGGCGCGGTGCTGCTGATCTACGACGAACTGCGT
CGCGTGCGCGGCTCGCGCTAA

Upstream 100 bases:

>100_bases
ACCGTGAAGATGTCGGCGCGCACGCTGATCATCCGACGCTGTGCGGCCGCTGCTTCTCCAACCTGTTCGAAAACGGCGAA
ATCCGGAGCGCTGCTTAACT

Downstream 100 bases:

>100_bases
GCGCGCATACTCGGCGTCGACGGCCGGCTTCGCGCCGGCCGTTCCGTTTGACCCTTGGAGGCCTGAGTTGGCACACGCAG
AACTCGCAGGAAAACACCTC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFVYGAQHELTSFFNLVLVYNRGAAFGFLSTAGGWQRWAFTALG
IAATLVICFLLKRHGQQRLFSLSLAMILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELR
RVRGSR

Sequences:

>Translated_166_residues
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFVYGAQHELTSFFNLVLVYNRGAAFGFLSTAGGWQRWAFTALG
IAATLVICFLLKRHGQQRLFSLSLAMILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELR
RVRGSR
>Mature_165_residues
AKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFVYGAQHELTSFFNLVLVYNRGAAFGFLSTAGGWQRWAFTALGI
AATLVICFLLKRHGQQRLFSLSLAMILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRR
VRGSR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=152, Percent_Identity=41.4473684210526, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18181; Mature: 18049

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFVYGAQHELTSFFNLVLVYNRGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AFGFLSTAGGWQRWAFTALGIAATLVICFLLKRHGQQRLFSLSLAMILGGALGNVIDRLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRRVRGSR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFVYGAQHELTSFFNLVLVYNRGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AFGFLSTAGGWQRWAFTALGIAATLVICFLLKRHGQQRLFSLSLAMILGGALGNVIDRLV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
YGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRRVRGSR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA