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The map label for this gene is rsmB [H]

Identifier: 78067310

GI number: 78067310

Start: 2955345

End: 2956610

Strand: Reverse

Name: rsmB [H]

Synonym: Bcep18194_A5841

Alternate gene names: 78067310

Gene position: 2956610-2955345 (Counterclockwise)

Preceding gene: 78067311

Following gene: 78067309

Centisome position: 80.04

GC content: 68.88

Gene sequence:

>1266_bases
ATGAAACTGCACGGATTCCTGATCGGCCAGACCGAGACTTTGTTGGCCGAGGTGCTGAAGTTCGCCGGCCCTGCCGATGC
GACGACGAGCCGGTTCTTCCGCGCGCACCCGAAGCTCGGGCATGCCGAGCGCGGCGTGATCGCCGAGGCGGTGTTCGCGG
TGCTGCGCCGGAAAATGGAGTTTTCGCACCTCGCCGAGAGCGGCACGGGCACGCCTGCGCGGCGCCTCACGCTGCTCGGC
CTGATGCAGACGGCTGGCCGTAATGCGCTGAAGCCGTTCCTGTCCGACACCGAGTCCGCATGGCTCGAGCACGTGTCGAA
GATCGACCCGGCGAGCCTGCCGGTGCGCATCCGTACGAACCTGCCCGACTGGATCCACCAGGCATTGTCGGCCCGTTTCG
ACGCCGACGAGCTCGCGCAACTCGCGGCCGCGCTGAACTACCCGGCGCCGCTCGACCTGCGTGCCAATGTGCAGAAGGCC
AGCCGTGATCAGGTCATCGACGGGTTGCGCGCGGAAGGCATCGATGCGGGCGCGACGCCGTTTTCGCCGTTCGGCGTGCG
CGTGGTCGGCAAGCCGGCGCTGACGCGCCTGAGGCTGTTCGAGGAAGGCGCGATCGAGGTGCAGGACGAAGGCAGCCAGC
TGCTGTGCTCGCTGGTCGCGCCGCGCCGCGGCGAGATGGTCGTCGATTTCTGCGCGGGCGCGGGCGGCAAGACGCTCGCG
CTGGGCGCGATGATGCGCTCGACCGGGCGACTCTACGCGTTCGACGTGTCGGAGAAGCGCCTGGCGAAGCTGAAGCCGCG
CCTTGCGCGCAGCGGGCTGTCGAACGTGAACCCCGTGCTGATCGACAGCGAGCACGACGCGAAGATCAAGCGGCTCGCCG
GCAAGATCGACCGCGTGCTGGTCGATGCGCCGTGCAGCGGCCTCGGCACGCTGCGCCGCAACCCGGACCTGAAGTGGCGC
CAGACGCGCACGGCGATCGACGAGCTGACGCCGAAGCAGGCGTCGATTCTCGCGAGCGCCGCGCGCCTGGTGAAGAAGGG
CGGCCGGCTCGTCTACGCGACCTGCAGCGTGCTCGACGCCGAGAACGAACGCATCGTCGAACAGTTCCTGGCTGACCATC
CCGAGTTCGTGCTGGTGCCGGCGCAGAAGGTGCTGGACGACCAGCGCATCGAGCTCGAGACGGGCGACTACCTGTCGCTA
TGGCCGCACCGCCACGCGACCGACGGCTTCTTCGCCGCGGTGCTCGAACGGCGCGCTGCGCAGTAA

Upstream 100 bases:

>100_bases
AGGGGCGTCTGCGCCTCGAGAACGGCCGTGCAGTGGTGGCGCCGGAAGAGGCGCGCTGGATTTTCGCGGATCAACCGCAT
ACCGAAACGAGTGAGGGCGT

Downstream 100 bases:

>100_bases
CGGCGGGCCGGACGGACGATGGAGAATCTGCAGAGTCGTCTGCTGTCGCACCGGCTGGCGTCGGTCATCCGCGATTTCCA
CCAGCCGGTGATGATCTGGC

Product: methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTAGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSARFDADELAQLAAALNYPAPLDLRANVQKA
SRDQVIDGLRAEGIDAGATPFSPFGVRVVGKPALTRLRLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFVLVPAQKVLDDQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Sequences:

>Translated_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTAGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSARFDADELAQLAAALNYPAPLDLRANVQKA
SRDQVIDGLRAEGIDAGATPFSPFGVRVVGKPALTRLRLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFVLVPAQKVLDDQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ
>Mature_421_residues
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKMEFSHLAESGTGTPARRLTLLG
LMQTAGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTNLPDWIHQALSARFDADELAQLAAALNYPAPLDLRANVQKA
SRDQVIDGLRAEGIDAGATPFSPFGVRVVGKPALTRLRLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDAENERIVEQFLADHPEFVLVPAQKVLDDQRIELETGDYLSL
WPHRHATDGFFAAVLERRAAQ

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=322, Percent_Identity=29.1925465838509, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI76150623, Length=322, Percent_Identity=29.1925465838509, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI270288816, Length=295, Percent_Identity=29.4915254237288, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI270288818, Length=295, Percent_Identity=29.4915254237288, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI23199998, Length=295, Percent_Identity=29.4915254237288, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI8922322, Length=295, Percent_Identity=29.4915254237288, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI32698918, Length=186, Percent_Identity=30.1075268817204, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI39995082, Length=201, Percent_Identity=31.8407960199005, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI301336155, Length=201, Percent_Identity=31.8407960199005, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI40316918, Length=189, Percent_Identity=31.2169312169312, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=259, Percent_Identity=32.4324324324324, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI87081985, Length=225, Percent_Identity=28.8888888888889, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17536757, Length=295, Percent_Identity=28.8135593220339, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115534021, Length=228, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71998419, Length=228, Percent_Identity=31.5789473684211, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=290, Percent_Identity=28.6206896551724, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=26.4516129032258, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=268, Percent_Identity=29.1044776119403, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI22024126, Length=302, Percent_Identity=26.8211920529801, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356579, Length=327, Percent_Identity=26.2996941896024, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355201, Length=191, Percent_Identity=30.8900523560209, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356513, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668781, Length=192, Percent_Identity=30.2083333333333, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920494, Length=154, Percent_Identity=33.1168831168831, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 46040; Mature: 46040

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FSHLAESGTGTPARRLTLLGLMQTAGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTN
HHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
LPDWIHQALSARFDADELAQLAAALNYPAPLDLRANVQKASRDQVIDGLRAEGIDAGATP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FSPFGVRVVGKPALTRLRLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDA
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCC
ENERIVEQFLADHPEFVLVPAQKVLDDQRIELETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECCHHHCCCCCEEECCCCEEEECCCCCCCCHHHHHHHHHHCC
Q
C
>Mature Secondary Structure
MKLHGFLIGQTETLLAEVLKFAGPADATTSRFFRAHPKLGHAERGVIAEAVFAVLRRKME
CCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FSHLAESGTGTPARRLTLLGLMQTAGRNALKPFLSDTESAWLEHVSKIDPASLPVRIRTN
HHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEECC
LPDWIHQALSARFDADELAQLAAALNYPAPLDLRANVQKASRDQVIDGLRAEGIDAGATP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
FSPFGVRVVGKPALTRLRLFEEGAIEVQDEGSQLLCSLVAPRRGEMVVDFCAGAGGKTLA
CCCCCEEEECCHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCHHH
LGAMMRSTGRLYAFDVSEKRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQTRTAIDELTPKQASILASAARLVKKGGRLVYATCSVLDA
EECCCCCCHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEHHCC
ENERIVEQFLADHPEFVLVPAQKVLDDQRIELETGDYLSLWPHRHATDGFFAAVLERRAA
CHHHHHHHHHHCCCCEEEECCHHHCCCCCEEECCCCEEEECCCCCCCCHHHHHHHHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]