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The map label for this gene is flbA [H]

Identifier: 78067278

GI number: 78067278

Start: 2924531

End: 2926171

Strand: Direct

Name: flbA [H]

Synonym: Bcep18194_A5809

Alternate gene names: 78067278

Gene position: 2924531-2926171 (Clockwise)

Preceding gene: 78067277

Following gene: 78067280

Centisome position: 79.17

GC content: 46.62

Gene sequence:

>1641_bases
ATGAAATTGCGTCCGACCACTTGGCAACCCAACGCATTGAAACCCATGCACCCACCTCACCCAGACACCCTCGAACTAGC
CACACTCTTATATCACGAGCAAAAATTCTCCGACGCCTATCACATCGCCAGGAATTTACTAAAATCAGAACCGCACAATG
CTTTTGTCTTGAATTTTGCCGGCGCGTGCTGTTATGCCACCGACAACGTCAAAGATGCCGAAAGATATTGGAAAACGGCC
ATCGATATTCAACCCACCTGGATCGACTCTCACAACAACTTAGGAACGCTGTACTGGAAGAAGATGCGTCAACCAGATAG
CGCCGAAAAATTTTTCAGAACAGCGCTGTCGATCGACAACCATCGAAAAGATGTTCAAGATAATTTGATCGAATGCTTTA
TAGACTTTGGAAAATTCCCGGATGCCATAGAATTATGTAGATCCGCAATGATCGATCGACCTACAGACTCCGGACTTGCT
CACAATCTTGGCATGGCGCTACATCAACTTGATCGATTGGAGGAGGCGGAATATTTTTACAAACTTGCAATAGAGAACAA
TCCGCGCCATCACTTTGCAAGCTCCAATCTCGGAGTCATCTTTAGAGAATTACGTCGCTACGATGAAGCTGAGCAAGCTT
ATCGCAATGCCATCGCAATATGCCCTGATGAACCGCTTCATCACATCAATCTTGGCGCACTACTAATTGAAACCGGTCGA
TGGAAGGAGGGCTGGGAGTGCGTAGAATGGCGGCATCGTCGAATCTCCGACGAATTTATACACAACCTCATTTCGACAAA
AATTAAAAGGTGGCATGGGGAGGCATTGCAACACAAATCATTGTTGATTATTCCAGAACAAGGATTTGGCGATCAAATTC
AAATGGTTAGATATATCGCAGCCGTGAAAAAACTCGGTGCAGCGCATATCACTCTGGCTTGCAGCCCCGAGTTACGCACG
CTCTTTAGATCAGTTTCCGGCGCCGACGACGTAACCACACCGACGAAGGCCATCAAGCGAAGGCATTATGATTTCTGGAT
TTCCATTTTCAGCCTTCCACATTTGATCAGTGCGACATCCGACGCCGTACCGAATACGATTCCCTATATCTTCGCTCCAA
AAAAATCAATCGGCAAATGGAAGAAAATAGTCCCAAGGGACACCATGCAGATTGGTTTGGTTTGGAGGGGTTCTCCACAT
CACGAATCCGACGCTTTTCGATCCTTGCCGAGCCTCTCAACACTGGCACCTTTATGGGAGATCAAAGGAATTAGCTATAT
CAGCCTCCAAAGAGGGACTGCCAGAGAAGAAATAACACGCCTCCGTGAAAAACAGCCTTTACGTGATCTCGGAGAAGAAA
TAGAGGATTTTGGCGATACCGCAGCAATTGTAACGCAACTTGATTTGGTAATTACGGTTGACACGTCGATGGCGCACCTC
TGCGGCGCACTTGGCGTGCCGTGCTGGATGTTGCTTTCAGCTATCCGAACAGACTGGAGATGGACCGGATTTTCAGAGAC
ATCAATCTGGTATCCACATAAGCTAAAGATATATAGACAAATTCAACGCGGCGATTGGCGAGCAGTCGTCAATAATGTCA
CACGGGATTTGGAAATATTAAAAAAGTCCCGCGACACATAA

Upstream 100 bases:

>100_bases
ATGAGGTCGCAAATCGCTGATAAGAAACACCTATTCATCTAAAAATTCGCTGCCGAATAAAAATCACGCACATCACAATT
GCTGTTGCGAATCGCGAGAG

Downstream 100 bases:

>100_bases
CCCGATTTTTGAACCAATCTTTTTAGACACAAAAGTATTTTCCGATCAATGCCAACCGCATTATTCACATGTACTGGATG
CGTTCGAGCAACCGACTAGC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKLRPTTWQPNALKPMHPPHPDTLELATLLYHEQKFSDAYHIARNLLKSEPHNAFVLNFAGACCYATDNVKDAERYWKTA
IDIQPTWIDSHNNLGTLYWKKMRQPDSAEKFFRTALSIDNHRKDVQDNLIECFIDFGKFPDAIELCRSAMIDRPTDSGLA
HNLGMALHQLDRLEEAEYFYKLAIENNPRHHFASSNLGVIFRELRRYDEAEQAYRNAIAICPDEPLHHINLGALLIETGR
WKEGWECVEWRHRRISDEFIHNLISTKIKRWHGEALQHKSLLIIPEQGFGDQIQMVRYIAAVKKLGAAHITLACSPELRT
LFRSVSGADDVTTPTKAIKRRHYDFWISIFSLPHLISATSDAVPNTIPYIFAPKKSIGKWKKIVPRDTMQIGLVWRGSPH
HESDAFRSLPSLSTLAPLWEIKGISYISLQRGTAREEITRLREKQPLRDLGEEIEDFGDTAAIVTQLDLVITVDTSMAHL
CGALGVPCWMLLSAIRTDWRWTGFSETSIWYPHKLKIYRQIQRGDWRAVVNNVTRDLEILKKSRDT

Sequences:

>Translated_546_residues
MKLRPTTWQPNALKPMHPPHPDTLELATLLYHEQKFSDAYHIARNLLKSEPHNAFVLNFAGACCYATDNVKDAERYWKTA
IDIQPTWIDSHNNLGTLYWKKMRQPDSAEKFFRTALSIDNHRKDVQDNLIECFIDFGKFPDAIELCRSAMIDRPTDSGLA
HNLGMALHQLDRLEEAEYFYKLAIENNPRHHFASSNLGVIFRELRRYDEAEQAYRNAIAICPDEPLHHINLGALLIETGR
WKEGWECVEWRHRRISDEFIHNLISTKIKRWHGEALQHKSLLIIPEQGFGDQIQMVRYIAAVKKLGAAHITLACSPELRT
LFRSVSGADDVTTPTKAIKRRHYDFWISIFSLPHLISATSDAVPNTIPYIFAPKKSIGKWKKIVPRDTMQIGLVWRGSPH
HESDAFRSLPSLSTLAPLWEIKGISYISLQRGTAREEITRLREKQPLRDLGEEIEDFGDTAAIVTQLDLVITVDTSMAHL
CGALGVPCWMLLSAIRTDWRWTGFSETSIWYPHKLKIYRQIQRGDWRAVVNNVTRDLEILKKSRDT
>Mature_546_residues
MKLRPTTWQPNALKPMHPPHPDTLELATLLYHEQKFSDAYHIARNLLKSEPHNAFVLNFAGACCYATDNVKDAERYWKTA
IDIQPTWIDSHNNLGTLYWKKMRQPDSAEKFFRTALSIDNHRKDVQDNLIECFIDFGKFPDAIELCRSAMIDRPTDSGLA
HNLGMALHQLDRLEEAEYFYKLAIENNPRHHFASSNLGVIFRELRRYDEAEQAYRNAIAICPDEPLHHINLGALLIETGR
WKEGWECVEWRHRRISDEFIHNLISTKIKRWHGEALQHKSLLIIPEQGFGDQIQMVRYIAAVKKLGAAHITLACSPELRT
LFRSVSGADDVTTPTKAIKRRHYDFWISIFSLPHLISATSDAVPNTIPYIFAPKKSIGKWKKIVPRDTMQIGLVWRGSPH
HESDAFRSLPSLSTLAPLWEIKGISYISLQRGTAREEITRLREKQPLRDLGEEIEDFGDTAAIVTQLDLVITVDTSMAHL
CGALGVPCWMLLSAIRTDWRWTGFSETSIWYPHKLKIYRQIQRGDWRAVVNNVTRDLEILKKSRDT

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI301336134, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI83415184, Length=220, Percent_Identity=26.8181818181818, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI32307148, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI32307150, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI118766330, Length=153, Percent_Identity=32.6797385620915, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI118766328, Length=153, Percent_Identity=32.6797385620915, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647755, Length=224, Percent_Identity=29.4642857142857, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585827, Length=224, Percent_Identity=29.4642857142857, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24585829, Length=224, Percent_Identity=29.4642857142857, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 62942; Mature: 62942

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPTTWQPNALKPMHPPHPDTLELATLLYHEQKFSDAYHIARNLLKSEPHNAFVLNFA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GACCYATDNVKDAERYWKTAIDIQPTWIDSHNNLGTLYWKKMRQPDSAEKFFRTALSIDN
CEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
HRKDVQDNLIECFIDFGKFPDAIELCRSAMIDRPTDSGLAHNLGMALHQLDRLEEAEYFY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
KLAIENNPRHHFASSNLGVIFRELRRYDEAEQAYRNAIAICPDEPLHHINLGALLIETGR
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEECCCEEEEECCC
WKEGWECVEWRHRRISDEFIHNLISTKIKRWHGEALQHKSLLIIPEQGFGDQIQMVRYIA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
AVKKLGAAHITLACSPELRTLFRSVSGADDVTTPTKAIKRRHYDFWISIFSLPHLISATS
HHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAVPNTIPYIFAPKKSIGKWKKIVPRDTMQIGLVWRGSPHHESDAFRSLPSLSTLAPLWE
CCCCCCCCEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHCCCCHHHHHHHHH
IKGISYISLQRGTAREEITRLREKQPLRDLGEEIEDFGDTAAIVTQLDLVITVDTSMAHL
HCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHEEEEEEECCHHHHH
CGALGVPCWMLLSAIRTDWRWTGFSETSIWYPHKLKIYRQIQRGDWRAVVNNVTRDLEIL
HHHHCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KKSRDT
HHCCCC
>Mature Secondary Structure
MKLRPTTWQPNALKPMHPPHPDTLELATLLYHEQKFSDAYHIARNLLKSEPHNAFVLNFA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GACCYATDNVKDAERYWKTAIDIQPTWIDSHNNLGTLYWKKMRQPDSAEKFFRTALSIDN
CEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHH
HRKDVQDNLIECFIDFGKFPDAIELCRSAMIDRPTDSGLAHNLGMALHQLDRLEEAEYFY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
KLAIENNPRHHFASSNLGVIFRELRRYDEAEQAYRNAIAICPDEPLHHINLGALLIETGR
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCEECCCEEEEECCC
WKEGWECVEWRHRRISDEFIHNLISTKIKRWHGEALQHKSLLIIPEQGFGDQIQMVRYIA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHH
AVKKLGAAHITLACSPELRTLFRSVSGADDVTTPTKAIKRRHYDFWISIFSLPHLISATS
HHHHCCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAVPNTIPYIFAPKKSIGKWKKIVPRDTMQIGLVWRGSPHHESDAFRSLPSLSTLAPLWE
CCCCCCCCEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHCCCCHHHHHHHHH
IKGISYISLQRGTAREEITRLREKQPLRDLGEEIEDFGDTAAIVTQLDLVITVDTSMAHL
HCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHEEEEEEECCHHHHH
CGALGVPCWMLLSAIRTDWRWTGFSETSIWYPHKLKIYRQIQRGDWRAVVNNVTRDLEIL
HHHHCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KKSRDT
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748431; 11259647; 1699845 [H]