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The map label for this gene is cobT

Identifier: 78067253

GI number: 78067253

Start: 2898960

End: 2900015

Strand: Reverse

Name: cobT

Synonym: Bcep18194_A5784

Alternate gene names: 78067253

Gene position: 2900015-2898960 (Counterclockwise)

Preceding gene: 78067254

Following gene: 78067252

Centisome position: 78.5

GC content: 70.27

Gene sequence:

>1056_bases
ATGACGACCTCGACCCACTTCCCGCCCGCGATCGCGCCGCTCGACGATGTGCTGCGCAAGCGCCTGCAGCACGTGATCGA
CCACAAGACCAAGCCGCCCGGCAGCCTTGGCCAGCTCGAGGCGATCGCGCTGCAGATCGGCCTGATCCAGCACACCGAGC
GGCCGGTCGTGCAGCGTCCGGTGATGATCGTGTTTGCCGGTGATCACGGGATTGCCGTCGAGGGCGTGAGTCCTTATCCG
CAAGCGGTGACCGCGCAGATGGTCGCGAACTTCCTCGCCGGCGGAGCGGCAATCAACGCGTTCTCGGGCGTCGCGCAGAG
CACGCTCGAGATCGTCGATGCGGGTGTTGCGTCGCCGCTGCCGCTGTCCGACCGGCTGGTGTCGCTGCCGGTCGCGCGCG
GGACGCGCAACTTCGCGGCGGAGCCGGCGATGACGCGCGACGAGGCGATGACGGCACTCGCGGCCGGCGCGGCGCGCGTG
CGCCTGCACGCGTCGCTCGGCACGAACGTGATCGGCTTCGGCGAGATGGGGATCGCGAACACGTCGTCGGCCGCGTGCCT
GATGAGCCGCCTGCTCAGCGTGCCGATCGACGCGTGCGTCGGGCGCGGCACCGGCCTCGACGACCAGGGCCTCGCGCACA
AGCGTGCGGTGCTCGGCCGTGCGCTCGTCAAGCACTCGCACGCCATTGCACCGCTCGATGTGCTCGCGACGTTCGGCGGC
TTCGAGATCGCGATGATGACGGGCGCGTATCTCGCGGCCGCGAGCGAGCGGATGACGATCCTCGTCGACGGCTTCATCGC
GACGGCCGCGCTGCTGGTTGCCGAGCGCATCGCGCCCGGCGTGCGCGACTACTGCGTGTTCTCACATACGTCGCACGAGG
CCGGACACCGGCGCATGCTCGAGCATTTCGGCGCGAAGACGCTGCTCGCGCTCGACCTGCGGCTCGGCGAAGGCACGGGC
GCCGCGCTTGCGCTGCCGCTCGTGCGTGCGGCGGCTGCGTTCCTCACGGAGATGGCGAGCTTCGAATCCGCCGGCGTCGA
CAATCGTGACGCCTGA

Upstream 100 bases:

>100_bases
GAGAATGGCCGCGATGCGCTGCTGCCGGCGTGGCCCGAGCGACAATGACCCTTTCTTTTCCGATGCGCGGCGCACACCGC
GCCAACGACACGGCTTTTCG

Downstream 100 bases:

>100_bases
TCGCGCGCGCGGCGTGCAGGCCGAACTGCGCTACTTCTTTGTCGCGCTCGGCTATTTCACACGCGTGCCCGTGCCGCGCT
CGATCGGCTACGCAGCCGGC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTTSTHFPPAIAPLDDVLRKRLQHVIDHKTKPPGSLGQLEAIALQIGLIQHTERPVVQRPVMIVFAGDHGIAVEGVSPYP
QAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVASPLPLSDRLVSLPVARGTRNFAAEPAMTRDEAMTALAAGAARV
RLHASLGTNVIGFGEMGIANTSSAACLMSRLLSVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKTLLALDLRLGEGTG
AALALPLVRAAAAFLTEMASFESAGVDNRDA

Sequences:

>Translated_351_residues
MTTSTHFPPAIAPLDDVLRKRLQHVIDHKTKPPGSLGQLEAIALQIGLIQHTERPVVQRPVMIVFAGDHGIAVEGVSPYP
QAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVASPLPLSDRLVSLPVARGTRNFAAEPAMTRDEAMTALAAGAARV
RLHASLGTNVIGFGEMGIANTSSAACLMSRLLSVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKTLLALDLRLGEGTG
AALALPLVRAAAAFLTEMASFESAGVDNRDA
>Mature_350_residues
TTSTHFPPAIAPLDDVLRKRLQHVIDHKTKPPGSLGQLEAIALQIGLIQHTERPVVQRPVMIVFAGDHGIAVEGVSPYPQ
AVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVASPLPLSDRLVSLPVARGTRNFAAEPAMTRDEAMTALAAGAARVR
LHASLGTNVIGFGEMGIANTSSAACLMSRLLSVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGGF
EIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRMLEHFGAKTLLALDLRLGEGTGA
ALALPLVRAAAAFLTEMASFESAGVDNRDA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=340, Percent_Identity=35.2941176470588, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36541; Mature: 36409

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTHFPPAIAPLDDVLRKRLQHVIDHKTKPPGSLGQLEAIALQIGLIQHTERPVVQRP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCC
VMIVFAGDHGIAVEGVSPYPQAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVASPL
EEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
PLSDRLVSLPVARGTRNFAAEPAMTRDEAMTALAAGAARVRLHASLGTNVIGFGEMGIAN
CCCCHHEECCHHCCCCCCCCCCCCCHHHHHHHHHHCHHHEEEEECCCCCEEEECCCCCCC
TSSAACLMSRLLSVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRML
EEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHH
EHFGAKTLLALDLRLGEGTGAALALPLVRAAAAFLTEMASFESAGVDNRDA
HHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTSTHFPPAIAPLDDVLRKRLQHVIDHKTKPPGSLGQLEAIALQIGLIQHTERPVVQRP
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCC
VMIVFAGDHGIAVEGVSPYPQAVTAQMVANFLAGGAAINAFSGVAQSTLEIVDAGVASPL
EEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
PLSDRLVSLPVARGTRNFAAEPAMTRDEAMTALAAGAARVRLHASLGTNVIGFGEMGIAN
CCCCHHEECCHHCCCCCCCCCCCCCHHHHHHHHHHCHHHEEEEECCCCCEEEECCCCCCC
TSSAACLMSRLLSVPIDACVGRGTGLDDQGLAHKRAVLGRALVKHSHAIAPLDVLATFGG
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
FEIAMMTGAYLAAASERMTILVDGFIATAALLVAERIAPGVRDYCVFSHTSHEAGHRRML
EEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHEEECCCCHHHHHHHHH
EHFGAKTLLALDLRLGEGTGAALALPLVRAAAAFLTEMASFESAGVDNRDA
HHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA