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The map label for this gene is dapL [H]

Identifier: 78066807

GI number: 78066807

Start: 2396812

End: 2398044

Strand: Direct

Name: dapL [H]

Synonym: Bcep18194_A5338

Alternate gene names: 78066807

Gene position: 2396812-2398044 (Clockwise)

Preceding gene: 78066801

Following gene: 78066808

Centisome position: 64.88

GC content: 68.61

Gene sequence:

>1233_bases
ATGGCCGCTTCGCCCGTGAACCCTCGACTCGACTCGCTCCAGCCCTATCCCTTCGAAAAGCTGCGCGCCCTGTTCAAGGA
CGTGACGCCCTCCGGCGCCCTCAAACCGATCAGCTTCGGCATCGGCGAGCCCAAACATGCCACCCCGGCGCTGATCCGCG
ACGCCGTGGTCGCAGCGCTCGACGGTCTCGCGTCGTACCCGGCCACCGCCGGCTCGGACGCGCTGCGCACGTCGATCGCG
CACTGGCTCGAGCGCCGCTACGGGCTGCCGGCCATCGATCCGGCCACGCAGGTGCTGCCCGTGTCGGGGTCGCGCGAGGC
GCTGTTCTCGCTTGCGCAGACGGTGATCGACGCACGCCCGTCCGAACAGGGCGAGAAGGCGATCGTACTCTGTCCGAATC
CTTTCTATCAAATTTACGAAGGCGCCGCGCTGCTGGCCGGTGCCGAACCCTATTTCGCGAACAGCGACCCGGCCCGCAAC
TTCGCGTGCGACTACGCGTCCGTGCCGGACGCGGTCTGGGCGCGCACGCAACTGCTGTACGTCTGCTCGCCGGGCAACCC
GACGGGCGCCGTGCTGACGCTCGACGACTGGCGCGAGTTGTTCGCGCTGTCCGACCGCCACGGTTTCGTGATCGCGTCCG
ACGAGTGCTATTCGGAAATCTATTTCGACGAAGCGGCGCCGCCGCTCGGCGGCCTCGAGGCCGCGCACCGCCTCGGCCGC
GGCTTCGAGCGGCTCGTGATGCTGTCGAGCCTGTCGAAGCGCTCGAACGTGCCGGGCATGCGCTCGGGCTTCGTCGCCGG
CGACGCGGCGCTGCTGAAGAAATTCCTGCTGTACCGCACGTACCACGGCGCGGCGCTGTCGCCGGTCTGGCAGCACGCGA
GCATCGCCGCGTGGAACGACGAGGCGCACGTGCGCGAGAACCGCGCGCTGTACCTGCAGAAGTTCAATACCGTCACGCCG
CTGCTGGCCGACGTGATCGACGTGAAGCTGCCCGACGCGGCGTTCTACCTGTGGGCCAACGTGTCGCGCACCGGGCTGTC
GGACACCGAGTTCGCCCGCCGCCTGTACGCCGACTATAATGTGACGGTTCTGCCCGGCTCGTACCTGGCGCGCGACGCGC
ACGGCACGAATCCGGGCCGCGATTTCATCCGGATCGCGCTCGTCGCGGGCACCCCCGAATGCGTCGAGGGCGCGCAACGC
ATCGTCGATTTCTGCCGCTCTCTCGCGCGGTAA

Upstream 100 bases:

>100_bases
TTCCGTCACGCTATAATCGTCCGTTGCGACCCGCGCGCCATCGGCGCCCGTTCGCAGCCGCGCGGCGCGCCCGCCGCTTC
TTTCGCTCCAACCGGCCGCG

Downstream 100 bases:

>100_bases
TCGTCCATCCGATCAATTCCATCCATCTCCTGCGAAAACGAACATGTCGCAACAACTTCAGCAAATCATCGATACCGCCT
GGGAAAACCGCGCCGAGCTG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGALKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIA
HWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSEQGEKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYASVPDAVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTP
LLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRSLAR

Sequences:

>Translated_410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGALKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIA
HWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSEQGEKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYASVPDAVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTP
LLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRSLAR
>Mature_409_residues
AASPVNPRLDSLQPYPFEKLRALFKDVTPSGALKPISFGIGEPKHATPALIRDAVVAALDGLASYPATAGSDALRTSIAH
WLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARPSEQGEKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNF
ACDYASVPDAVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGRG
FERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFNTVTPL
LADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYNVTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRI
VDFCRSLAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=275, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI169881279, Length=275, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI56713256, Length=335, Percent_Identity=22.9850746268657, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI56713254, Length=335, Percent_Identity=22.9850746268657, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788722, Length=365, Percent_Identity=27.3972602739726, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787909, Length=390, Percent_Identity=24.3589743589744, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=24.2105263157895, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859735, Length=402, Percent_Identity=24.1293532338308, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44619; Mature: 44488

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPVNPRLDSLQPYPFEKLRALFKDVTPSGALKPISFGIGEPKHATPALIRDAVVAAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGSDALRTSIAHWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCC
SEQGEKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYASVPDAVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFNTVTPLLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYN
CHHHHCCCEEEEHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
VTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRSLAR
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASPVNPRLDSLQPYPFEKLRALFKDVTPSGALKPISFGIGEPKHATPALIRDAVVAAL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGSDALRTSIAHWLERRYGLPAIDPATQVLPVSGSREALFSLAQTVIDARP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCC
SEQGEKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYASVPDAVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEAAPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFNTVTPLLADVIDVKLPDAAFYLWANVSRTGLSDTEFARRLYADYN
CHHHHCCCEEEEHHHCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCC
VTVLPGSYLARDAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRSLAR
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA