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The map label for this gene is atzB [H]

Identifier: 78066736

GI number: 78066736

Start: 2323081

End: 2324493

Strand: Reverse

Name: atzB [H]

Synonym: Bcep18194_A5267

Alternate gene names: 78066736

Gene position: 2324493-2323081 (Counterclockwise)

Preceding gene: 78066739

Following gene: 78066733

Centisome position: 62.92

GC content: 68.37

Gene sequence:

>1413_bases
ATGAACCTCGAGCAGCACGCTGGCGCACGCGCGCCGAACACTTCCTCATCCCGCCCGAAAACCCTGCTGGTCAAGCACGC
CGACGTGCTCGTGACCATGGACGACACGCGCCGCGAGCTGCGCGACGCGGGGCTCTACATCGAAGACAACCGGATCGTCG
CGGTCGGCCCGACCGCTGAGCTGCCCGATACGGCGGACGAAGTGCTCGACCTGCGCGGCCACCTCGTGATTCCGGGCCTC
GTGAACACGCATCACCACATGTACCAGAGCCTGACGCGCGCGGTGCCTGCGGCGCAGAACGCCGAGCTGTTCGGCTGGCT
CACGAACCTCTACAAGATCTGGGCGCACCTGACGCCCGAGATGATCGAAGTGTCGACGCTCACCGCGATGGCCGAGCTGC
TGCAGTCGGGCTGCACGACGTCGAGCGATCATCTGTACATCTACCCGAACGGCAGCCGCCTCGACGACAGCATCGGCGCC
GCGCAGCGGATCGGCATGCGTTTTCATGCGAGCCGCGGTGCGATGAGCGTCGGCCAGCGCGATGGCGGGTTGCCGCCCGA
TTCGGTCGTCGAGCGCGAGCCCGACATCCTGCGCGACACACAGCGCCTGATCGAGACCTATCACGATGAAGGCCGCTACG
CGATGCTGCGCGTGGTCGTCGCGCCGTGCTCGCCGTTCTCGGTGAGCCGCGACCTGATGCGCGACGCGGCCGTGCTCGCA
CGCGAATACGGCGTGTCGCTGCACACGCACCTCGCGGAGAACGTCAACGACATCGCGTACAGCCGCGAGAAATTCGGGAT
GACGCCCGCCGAATATGCGGAAGATCTCGGCTGGGTCGGCCACGACGTGTGGCATGCGCACTGCGTGCAGCTCGACGATG
CGGGCATCAGCCTGTTCGCGCGCACCGGTACGGGCGTCGCGCACTGTCCGTGCTCGAACATGCGGCTCGCGTCGGGTATC
GCGCCGGTGAAGAAGATGCGTCTCGCGGGCGTGCCGGTCGGCCTCGGCGTCGACGGCTCCGCATCGAACGACGGCGCGCA
GATGGTGGCGGAAGTGCGGCAGGCGCTGCTGCTGCAGCGGGTCGGTTTCGGGCCCGATGCGATGACCGCGCGTGAAGCGC
TCGAAATCGCGACGCTCGGCGGCGCGAAGGTGCTGAACCGTGACGATATCGGCGCGCTGAAGCCGGGCATGGCCGCGGAC
TTCGCCGCATTCGACCTGCGCCAGCCGCTGTTCGCGGGCGCGCTGCACGATCCGGTCGCGGCGCTCGTGTTCTGCGCGCC
GTCGCAGACGGCGTACACGGTGGTGAACGGGAAGGTGGTGGTGCGGGAAGGGCGTCTGGCGACGCTCGACCTGCCGCCCG
TTATCGCGCGTCACAACGCGCTCGCGCAGGCACTGGTCGAGGCATCGCGCTGA

Upstream 100 bases:

>100_bases
CGAACGGACGCAGGCACCGGAGCGTGCCGCGATTCAACGTTCGAACGTGTGTGACCGTCCCCAGGATCCGCCCCTGGGGG
CAGACCGACGCGGAGAACGC

Downstream 100 bases:

>100_bases
AGGAAGGCTGACGCCATCCGGCGGCCGTGTTGCCGCCAGCTGTCGCCACGCCGCGCCGGGACGGCGCGGGCGGCGCATGC
CGTTACGGCTCGATCAGCGT

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNLEQHAGARAPNTSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPTAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYKIWAHLTPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGISLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIARHNALAQALVEASR

Sequences:

>Translated_470_residues
MNLEQHAGARAPNTSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPTAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYKIWAHLTPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGISLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIARHNALAQALVEASR
>Mature_470_residues
MNLEQHAGARAPNTSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPTAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYKIWAHLTPEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRDAAVLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGISLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIARHNALAQALVEASR

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=347, Percent_Identity=24.4956772334294, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1789249, Length=440, Percent_Identity=29.5454545454545, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI87082177, Length=428, Percent_Identity=25, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540282, Length=404, Percent_Identity=23.7623762376238, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=345, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643849, Length=222, Percent_Identity=27.027027027027, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50721; Mature: 50721

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEQHAGARAPNTSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPTAE
CCCCHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYKIWAHLTPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRDAAVLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGISLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCEEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHE
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIARHNALAQALVEASR
EHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLEQHAGARAPNTSSSRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPTAE
CCCCHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYKIWAHLTPE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDTQRLIETYHDEGRYAMLRVVVAPCSPFSVSRDLMRDAAVLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGISLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCEEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHE
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIARHNALAQALVEASR
EHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]