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The map label for this gene is msrB [H]

Identifier: 78066679

GI number: 78066679

Start: 2259358

End: 2259789

Strand: Direct

Name: msrB [H]

Synonym: Bcep18194_A5210

Alternate gene names: 78066679

Gene position: 2259358-2259789 (Clockwise)

Preceding gene: 78066678

Following gene: 78066680

Centisome position: 61.16

GC content: 62.27

Gene sequence:

>432_bases
ATGTCCCACGATTCCGACGACAAGACCTTCCCGTACGAGAAGGACGACGCCGAGCTGCGCCGCCGGCTCACGCCGATGCA
GTACGAAGTCACGCAGCATGCGGCCACCGAGCGTGCGTTCACCGGCGAATACACCGACACCGAAGACGACGGCATCTACA
AATGCGTCGTCTGCAGCACGCCGCTGTTCGAATCCGGCTCCAAATTCCACTCGGGCTGCGGCTGGCCCAGCTACTTCAAG
CCGCTCAACGGCGAGGTGATCGACGAAAAGGTCGACTACTCGCACGGGATGGTGCGTGTCGAGGTGCGCTGCAACCACTG
CGGCGCGCATCTCGGCCACGTCTTCGAGGACGGCCCGCGCGACCAGACCGGTTTGCGGTACTGCATCAATTCGGCTGCGT
TAAACTTCGAGTCCCGACCCGAAAACGAATGA

Upstream 100 bases:

>100_bases
ACGCGGCGTTGCCGCCCGACTGGGCCGGGTCGCTCGAAGTGAGCTGCTCGTCCTGAGCCCCAACCCGCGCGTATCGACCG
ACCGATCAGGAGAACCCCAC

Downstream 100 bases:

>100_bases
GCGGCGCCGGGCGGATCCGCGGGGCGCCCCTCACGCCGCCCGATCCGCTCCGGCGGTGCCTGGCGGGTCCCTACAACGGT
GAAAGGCCGCGCAAGCGGCC

Product: protein-methionine-S-oxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MSHDSDDKTFPYEKDDAELRRRLTPMQYEVTQHAATERAFTGEYTDTEDDGIYKCVVCSTPLFESGSKFHSGCGWPSYFK
PLNGEVIDEKVDYSHGMVRVEVRCNHCGAHLGHVFEDGPRDQTGLRYCINSAALNFESRPENE

Sequences:

>Translated_143_residues
MSHDSDDKTFPYEKDDAELRRRLTPMQYEVTQHAATERAFTGEYTDTEDDGIYKCVVCSTPLFESGSKFHSGCGWPSYFK
PLNGEVIDEKVDYSHGMVRVEVRCNHCGAHLGHVFEDGPRDQTGLRYCINSAALNFESRPENE
>Mature_142_residues
SHDSDDKTFPYEKDDAELRRRLTPMQYEVTQHAATERAFTGEYTDTEDDGIYKCVVCSTPLFESGSKFHSGCGWPSYFKP
LNGEVIDEKVDYSHGMVRVEVRCNHCGAHLGHVFEDGPRDQTGLRYCINSAALNFESRPENE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=119, Percent_Identity=64.7058823529412, Blast_Score=161, Evalue=2e-40,
Organism=Homo sapiens, GI301336164, Length=119, Percent_Identity=64.7058823529412, Blast_Score=161, Evalue=2e-40,
Organism=Homo sapiens, GI301336162, Length=119, Percent_Identity=64.7058823529412, Blast_Score=161, Evalue=2e-40,
Organism=Homo sapiens, GI73089054, Length=119, Percent_Identity=64.7058823529412, Blast_Score=161, Evalue=2e-40,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=44.2748091603053, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=52.9411764705882, Blast_Score=139, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17553450, Length=130, Percent_Identity=43.8461538461538, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=130, Percent_Identity=43.8461538461538, Blast_Score=115, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=40.7692307692308, Blast_Score=103, Evalue=8e-24,
Organism=Drosophila melanogaster, GI221378664, Length=132, Percent_Identity=49.2424242424242, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI221378662, Length=139, Percent_Identity=47.4820143884892, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645799, Length=132, Percent_Identity=49.2424242424242, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=132, Percent_Identity=49.2424242424242, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=132, Percent_Identity=49.2424242424242, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645801, Length=143, Percent_Identity=45.4545454545455, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24645804, Length=143, Percent_Identity=45.4545454545455, Blast_Score=125, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16277; Mature: 16146

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDSDDKTFPYEKDDAELRRRLTPMQYEVTQHAATERAFTGEYTDTEDDGIYKCVVCST
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
PLFESGSKFHSGCGWPSYFKPLNGEVIDEKVDYSHGMVRVEVRCNHCGAHLGHVFEDGPR
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCC
DQTGLRYCINSAALNFESRPENE
CCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SHDSDDKTFPYEKDDAELRRRLTPMQYEVTQHAATERAFTGEYTDTEDDGIYKCVVCST
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
PLFESGSKFHSGCGWPSYFKPLNGEVIDEKVDYSHGMVRVEVRCNHCGAHLGHVFEDGPR
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCC
DQTGLRYCINSAALNFESRPENE
CCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA