Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 78066471

GI number: 78066471

Start: 2037900

End: 2040707

Strand: Reverse

Name: cirA [H]

Synonym: Bcep18194_A5002

Alternate gene names: 78066471

Gene position: 2040707-2037900 (Counterclockwise)

Preceding gene: 78066472

Following gene: 78066470

Centisome position: 55.24

GC content: 65.31

Gene sequence:

>2808_bases
ATGAAGCAGAGAGTTTTGGCGTTGGCCATCAAGAGGATAGTCTGGGCGGAACTGGCGCTGACGGCCGCACTGGCGCCGCC
GGCGTTCGCCCAGAGCCAGCCGGCGCCGGGCGCCGTCGCGATCGCGGATGCGGTCGCGAGCGGCGCGCCCGTGACCGTTG
CACAGGCGGGCGGCACGCCGGGTGCCGCGGCTGCCACGGGCACCGCGGCGCCCGCGGCACCTGACGCAGCGGCCGGCGCG
GCAGCCGAGGTGACGCCCGCCGCACCGGGTGCGAACGGCCAGGGCAAGGTCGCGCAGATCAAGCGATTCGAAGTGACGGG
TTCGCTGATCCGGCAGGCCGACAAGACCGGCTTCCAGCAGGTGCAGACGATCACGCCGAAGGAAATCCAGGCCAGCGGCG
CGGTGACCGTCACCGACTTCCTGCGCGACGCGGCGGCGAACTCGGCGAACAGCTGGGGTGAAGGGCAATCGGGCAACTTT
GCGGCAGGCGCGGCCGGCATCGCGCTGCGCGGCCTGTCCGAGAAGTACACGCTCGTGATGGTCGACGGCCAGCGCGTCGC
ACCGTACGCATTCTTTTCGAACAGCGTCGATTCGTTCTTCGACCTCAACACGATCCCGCTCAACGATATCGAGCGAATCG
AAATCGTGAAGACGGGCGCCGTGTCGCAGTATGGTTCGGACGCGATCGGCGGTGTCGTCAACATCATCACGAAACACAAT
TTCCGCGGGCTGCAGCTCGACGGCAGCCTCGGCAGCGCGATCAACGCCGGTAACGGCGACGGCACGGTGAAGTTCGGCGT
GCTCGGCGGTTTCGGCGACCTGAACGCGGACCGCTTCAACGTGACGGCCGCGCTGAGCTACTACAAGTCGAACGGCTTCA
CGCTCGCCGACCGCGATTCGACGCGCAACCAGGACTTCACGGGCAAGCCGGGCGGCTTCTCGCTGCTCGCGCCGTCGTAC
TGGAACATGCCCGGCGGCGTCGCGCAGGCGCTGAGCGGCGGCTGCCCGTTCGGCGGCTCGGTGCATCCCGCGGTGTCGAA
TTCGCTGTCGGCCGGGTCGCCGGGCACGGTCTGCGGGTACAACACGGCTGAAAGCACGTCGATTCTGCCGATGACCGAGC
GCCTGAACGCGAAGCTCCATGCGGACTTCAAGATCGACGACAAGACGACCGCGTTCGCGGATTTTCTCGAGAGCTACAAC
ACGACCACGACCAACGACGGCTTGTGGAACAACGTGATCGGCAATTCGCAGAACCCGGCGCTCGTCTGGAATCCGCAGAC
GAAGCTGCTGTCACCGTTCAATTTCACGGTACCGGTCAGCAACCCGTACAACACGACAGGCGCGGCCACGCCGCTTACTT
ACGCATTTCCGAACACGGTCGCGCAGAAGACCTGGGCCAACTACTGGCGTGCGGCCGCCGGCATCAAGGGGTCGTTTACG
CTGCCGTACGGTGACTGGGACTGGGCGACGTCGGTCAGCCATTCGCAGAGCACGGTGTCGAACGTGTTCACGAACCAGCT
GAACGTCAACGCGCTGAACAACATCTACCAGAACGGCACGCTGAACTTCGCGAACCCGGCGGCAACGCCGAACGCGTTCA
ACGGGCTTTATCAGGAGGCGAACAACCTCGGCATCTCGAAGCTCGACACGATCGACGCGACGGTATCGACGCCGAACCTG
TTCCACCTGCCGGCGGGCGACGTCGGCATCGGCTTCGGTGCACAGTTCACGCACCAGAGCGAAACGCTGACACCGGGCTC
CGAATACCTGAGCGGGGCCGTCATCACGCCGGACCTCGAGACGGTGGATGGCCAGCGCAACGTCGCGGCCGTCTATTACC
AGATCAACGTGCCGATCCTCGAGAACCTGACGTTCAGCCAGGCGGGCCGCTACGACCACTACACGGACGTGGGCGGCGCC
TTCTCGCCGCGCTTCGCGTTGCGTTACCAGCCGATCAAGGCACTGACGCTGTATACGTCGTACAACCGCGGCTTCCGCGC
GCCGACCTTCGTCGAGGACAGCAAGTCGCAGACGCTCGGCATCCAGATCGACCCGGCCACCGGCCAGAACTACACGTCGA
TCACCGTCGGCAACCCGAACCTCGCGCCGGAACGCACGCGCAACTTCAACATCGGCTTCCAGGTGTCGCCGAGCCGGTAC
ACGGATATCGGCTTCGACTGGTACAAGATCCGCATCGACAACGTGATCGGCCAGGGCACGCCGTCGCAGATCGCGACCGA
CCCGACGACGGGCCAGCTGCTGTACAAGGTGATCCCGTACCAGAACCTCGGCTACCTCGACACCAACGGCTTCGAAGGCA
CGTTCCGCCAGGGCCTGCCGCTCAAGGGCTGGGGCACGGTCACGCTGTCGGGCGACTGGGCGTACATCAACAGCTACAAG
ATCGGCTTCCCGGGCGGCACGCCGGTCAACGGCGCGGGCAACAACTTCACGATCACGCAGCCGTTCGGCGGCAGCTTCCC
GCGCTGGCGCGGCAACACGACGCTGGACTGGAACTACCGGAAGTTCGATGCGGCGCTCACGTGGCAGTTCACGGGCCCGT
ACGCGCAGAACCTCACGCCGGCGCCCGCGCCGTCGAAGGTCGGTTCGTACAGCCAGTTCAACCTGATGATGTCGTACACG
GGCTTCAAGAACTGGACGATCTACGGCGGCATCAACAACCTCTTCAACCGCACGCCGCCGTACGACCCGATCTTCGCGAA
CGGCACGCTGGACCAGAGCGGGTACGACACGTCGGTGTATTCGTACATCGGCCGGTTCGCGCAGATCGGCGCGACGTACA
AGTTCTGA

Upstream 100 bases:

>100_bases
AATCGCGGGTTCCGGTACACGGGCACCCAGGACGCGCAAGGAATTCACAAGGTTCCGGCGCGCAGCAGGTGGGGTCTTAC
TACGAGCGAGAGGGAACAAG

Downstream 100 bases:

>100_bases
CGGCGATCGCGATGCACTGACAGGCTTTAGACCGGCCGCTCCACGTCCACTACCCCCTTTTCGGGGCGGCCTTTTTTCGC
CTGGCGCCACGACGGCCCGC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 935; Mature: 935

Protein sequence:

>935_residues
MKQRVLALAIKRIVWAELALTAALAPPAFAQSQPAPGAVAIADAVASGAPVTVAQAGGTPGAAAATGTAAPAAPDAAAGA
AAEVTPAAPGANGQGKVAQIKRFEVTGSLIRQADKTGFQQVQTITPKEIQASGAVTVTDFLRDAAANSANSWGEGQSGNF
AAGAAGIALRGLSEKYTLVMVDGQRVAPYAFFSNSVDSFFDLNTIPLNDIERIEIVKTGAVSQYGSDAIGGVVNIITKHN
FRGLQLDGSLGSAINAGNGDGTVKFGVLGGFGDLNADRFNVTAALSYYKSNGFTLADRDSTRNQDFTGKPGGFSLLAPSY
WNMPGGVAQALSGGCPFGGSVHPAVSNSLSAGSPGTVCGYNTAESTSILPMTERLNAKLHADFKIDDKTTAFADFLESYN
TTTTNDGLWNNVIGNSQNPALVWNPQTKLLSPFNFTVPVSNPYNTTGAATPLTYAFPNTVAQKTWANYWRAAAGIKGSFT
LPYGDWDWATSVSHSQSTVSNVFTNQLNVNALNNIYQNGTLNFANPAATPNAFNGLYQEANNLGISKLDTIDATVSTPNL
FHLPAGDVGIGFGAQFTHQSETLTPGSEYLSGAVITPDLETVDGQRNVAAVYYQINVPILENLTFSQAGRYDHYTDVGGA
FSPRFALRYQPIKALTLYTSYNRGFRAPTFVEDSKSQTLGIQIDPATGQNYTSITVGNPNLAPERTRNFNIGFQVSPSRY
TDIGFDWYKIRIDNVIGQGTPSQIATDPTTGQLLYKVIPYQNLGYLDTNGFEGTFRQGLPLKGWGTVTLSGDWAYINSYK
IGFPGGTPVNGAGNNFTITQPFGGSFPRWRGNTTLDWNYRKFDAALTWQFTGPYAQNLTPAPAPSKVGSYSQFNLMMSYT
GFKNWTIYGGINNLFNRTPPYDPIFANGTLDQSGYDTSVYSYIGRFAQIGATYKF

Sequences:

>Translated_935_residues
MKQRVLALAIKRIVWAELALTAALAPPAFAQSQPAPGAVAIADAVASGAPVTVAQAGGTPGAAAATGTAAPAAPDAAAGA
AAEVTPAAPGANGQGKVAQIKRFEVTGSLIRQADKTGFQQVQTITPKEIQASGAVTVTDFLRDAAANSANSWGEGQSGNF
AAGAAGIALRGLSEKYTLVMVDGQRVAPYAFFSNSVDSFFDLNTIPLNDIERIEIVKTGAVSQYGSDAIGGVVNIITKHN
FRGLQLDGSLGSAINAGNGDGTVKFGVLGGFGDLNADRFNVTAALSYYKSNGFTLADRDSTRNQDFTGKPGGFSLLAPSY
WNMPGGVAQALSGGCPFGGSVHPAVSNSLSAGSPGTVCGYNTAESTSILPMTERLNAKLHADFKIDDKTTAFADFLESYN
TTTTNDGLWNNVIGNSQNPALVWNPQTKLLSPFNFTVPVSNPYNTTGAATPLTYAFPNTVAQKTWANYWRAAAGIKGSFT
LPYGDWDWATSVSHSQSTVSNVFTNQLNVNALNNIYQNGTLNFANPAATPNAFNGLYQEANNLGISKLDTIDATVSTPNL
FHLPAGDVGIGFGAQFTHQSETLTPGSEYLSGAVITPDLETVDGQRNVAAVYYQINVPILENLTFSQAGRYDHYTDVGGA
FSPRFALRYQPIKALTLYTSYNRGFRAPTFVEDSKSQTLGIQIDPATGQNYTSITVGNPNLAPERTRNFNIGFQVSPSRY
TDIGFDWYKIRIDNVIGQGTPSQIATDPTTGQLLYKVIPYQNLGYLDTNGFEGTFRQGLPLKGWGTVTLSGDWAYINSYK
IGFPGGTPVNGAGNNFTITQPFGGSFPRWRGNTTLDWNYRKFDAALTWQFTGPYAQNLTPAPAPSKVGSYSQFNLMMSYT
GFKNWTIYGGINNLFNRTPPYDPIFANGTLDQSGYDTSVYSYIGRFAQIGATYKF
>Mature_935_residues
MKQRVLALAIKRIVWAELALTAALAPPAFAQSQPAPGAVAIADAVASGAPVTVAQAGGTPGAAAATGTAAPAAPDAAAGA
AAEVTPAAPGANGQGKVAQIKRFEVTGSLIRQADKTGFQQVQTITPKEIQASGAVTVTDFLRDAAANSANSWGEGQSGNF
AAGAAGIALRGLSEKYTLVMVDGQRVAPYAFFSNSVDSFFDLNTIPLNDIERIEIVKTGAVSQYGSDAIGGVVNIITKHN
FRGLQLDGSLGSAINAGNGDGTVKFGVLGGFGDLNADRFNVTAALSYYKSNGFTLADRDSTRNQDFTGKPGGFSLLAPSY
WNMPGGVAQALSGGCPFGGSVHPAVSNSLSAGSPGTVCGYNTAESTSILPMTERLNAKLHADFKIDDKTTAFADFLESYN
TTTTNDGLWNNVIGNSQNPALVWNPQTKLLSPFNFTVPVSNPYNTTGAATPLTYAFPNTVAQKTWANYWRAAAGIKGSFT
LPYGDWDWATSVSHSQSTVSNVFTNQLNVNALNNIYQNGTLNFANPAATPNAFNGLYQEANNLGISKLDTIDATVSTPNL
FHLPAGDVGIGFGAQFTHQSETLTPGSEYLSGAVITPDLETVDGQRNVAAVYYQINVPILENLTFSQAGRYDHYTDVGGA
FSPRFALRYQPIKALTLYTSYNRGFRAPTFVEDSKSQTLGIQIDPATGQNYTSITVGNPNLAPERTRNFNIGFQVSPSRY
TDIGFDWYKIRIDNVIGQGTPSQIATDPTTGQLLYKVIPYQNLGYLDTNGFEGTFRQGLPLKGWGTVTLSGDWAYINSYK
IGFPGGTPVNGAGNNFTITQPFGGSFPRWRGNTTLDWNYRKFDAALTWQFTGPYAQNLTPAPAPSKVGSYSQFNLMMSYT
GFKNWTIYGGINNLFNRTPPYDPIFANGTLDQSGYDTSVYSYIGRFAQIGATYKF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=135, Percent_Identity=38.5185185185185, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 99460; Mature: 99460

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRVLALAIKRIVWAELALTAALAPPAFAQSQPAPGAVAIADAVASGAPVTVAQAGGTP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCCEEEEECCCCC
GAAAATGTAAPAAPDAAAGAAAEVTPAAPGANGQGKVAQIKRFEVTGSLIRQADKTGFQQ
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
VQTITPKEIQASGAVTVTDFLRDAAANSANSWGEGQSGNFAAGAAGIALRGLSEKYTLVM
HHCCCCHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEECCCCCEEEEE
VDGQRVAPYAFFSNSVDSFFDLNTIPLNDIERIEIVKTGAVSQYGSDAIGGVVNIITKHN
ECCCEECCEEEECCCCHHHEECCCCCCCCCCEEEEEECCCCHHCCCCHHHHHHEEEECCC
FRGLQLDGSLGSAINAGNGDGTVKFGVLGGFGDLNADRFNVTAALSYYKSNGFTLADRDS
CCEEEECCCCCCCEECCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEECCCC
TRNQDFTGKPGGFSLLAPSYWNMPGGVAQALSGGCPFGGSVHPAVSNSLSAGSPGTVCGY
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEECC
NTAESTSILPMTERLNAKLHADFKIDDKTTAFADFLESYNTTTTNDGLWNNVIGNSQNPA
CCCCCCEEEEEHHHCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCE
LVWNPQTKLLSPFNFTVPVSNPYNTTGAATPLTYAFPNTVAQKTWANYWRAAAGIKGSFT
EEECCCHHEECCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEE
LPYGDWDWATSVSHSQSTVSNVFTNQLNVNALNNIYQNGTLNFANPAATPNAFNGLYQEA
CCCCCCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHH
NNLGISKLDTIDATVSTPNLFHLPAGDVGIGFGAQFTHQSETLTPGSEYLSGAVITPDLE
HCCCCCEECCCCEEECCCCEEECCCCCCCCCCCCEECCCCCCCCCCHHHHCCCEECCCHH
TVDGQRNVAAVYYQINVPILENLTFSQAGRYDHYTDVGGAFSPRFALRYQPIKALTLYTS
HCCCCCCEEEEEEEECCCHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEE
YNRGFRAPTFVEDSKSQTLGIQIDPATGQNYTSITVGNPNLAPERTRNFNIGFQVSPSRY
CCCCCCCCCEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
TDIGFDWYKIRIDNVIGQGTPSQIATDPTTGQLLYKVIPYQNLGYLDTNGFEGTFRQGLP
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHCCCC
LKGWGTVTLSGDWAYINSYKIGFPGGTPVNGAGNNFTITQPFGGSFPRWRGNTTLDWNYR
CCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCEE
KFDAALTWQFTGPYAQNLTPAPAPSKVGSYSQFNLMMSYTGFKNWTIYGGINNLFNRTPP
EEEEEEEEEECCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCHHHHHCCCCC
YDPIFANGTLDQSGYDTSVYSYIGRFAQIGATYKF
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKQRVLALAIKRIVWAELALTAALAPPAFAQSQPAPGAVAIADAVASGAPVTVAQAGGTP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHCCCCCEEEEECCCCC
GAAAATGTAAPAAPDAAAGAAAEVTPAAPGANGQGKVAQIKRFEVTGSLIRQADKTGFQQ
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHH
VQTITPKEIQASGAVTVTDFLRDAAANSANSWGEGQSGNFAAGAAGIALRGLSEKYTLVM
HHCCCCHHHHCCCCEEHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEECCCCCEEEEE
VDGQRVAPYAFFSNSVDSFFDLNTIPLNDIERIEIVKTGAVSQYGSDAIGGVVNIITKHN
ECCCEECCEEEECCCCHHHEECCCCCCCCCCEEEEEECCCCHHCCCCHHHHHHEEEECCC
FRGLQLDGSLGSAINAGNGDGTVKFGVLGGFGDLNADRFNVTAALSYYKSNGFTLADRDS
CCEEEECCCCCCCEECCCCCCEEEEEEEECCCCCCCCEEEEEEEEEEEECCCCEEECCCC
TRNQDFTGKPGGFSLLAPSYWNMPGGVAQALSGGCPFGGSVHPAVSNSLSAGSPGTVCGY
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEECC
NTAESTSILPMTERLNAKLHADFKIDDKTTAFADFLESYNTTTTNDGLWNNVIGNSQNPA
CCCCCCEEEEEHHHCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCE
LVWNPQTKLLSPFNFTVPVSNPYNTTGAATPLTYAFPNTVAQKTWANYWRAAAGIKGSFT
EEECCCHHEECCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEE
LPYGDWDWATSVSHSQSTVSNVFTNQLNVNALNNIYQNGTLNFANPAATPNAFNGLYQEA
CCCCCCCHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHH
NNLGISKLDTIDATVSTPNLFHLPAGDVGIGFGAQFTHQSETLTPGSEYLSGAVITPDLE
HCCCCCEECCCCEEECCCCEEECCCCCCCCCCCCEECCCCCCCCCCHHHHCCCEECCCHH
TVDGQRNVAAVYYQINVPILENLTFSQAGRYDHYTDVGGAFSPRFALRYQPIKALTLYTS
HCCCCCCEEEEEEEECCCHHHCCCHHHCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEE
YNRGFRAPTFVEDSKSQTLGIQIDPATGQNYTSITVGNPNLAPERTRNFNIGFQVSPSRY
CCCCCCCCCEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCC
TDIGFDWYKIRIDNVIGQGTPSQIATDPTTGQLLYKVIPYQNLGYLDTNGFEGTFRQGLP
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCCHHHCCCC
LKGWGTVTLSGDWAYINSYKIGFPGGTPVNGAGNNFTITQPFGGSFPRWRGNTTLDWNYR
CCCCEEEEECCCEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCEE
KFDAALTWQFTGPYAQNLTPAPAPSKVGSYSQFNLMMSYTGFKNWTIYGGINNLFNRTPP
EEEEEEEEEECCCHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCHHHHHCCCCC
YDPIFANGTLDQSGYDTSVYSYIGRFAQIGATYKF
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]