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The map label for this gene is trxB [H]

Identifier: 78066434

GI number: 78066434

Start: 1989736

End: 1991136

Strand: Direct

Name: trxB [H]

Synonym: Bcep18194_A4965

Alternate gene names: 78066434

Gene position: 1989736-1991136 (Clockwise)

Preceding gene: 78066421

Following gene: 78066437

Centisome position: 53.86

GC content: 56.75

Gene sequence:

>1401_bases
ATGTCATGTCGCTCGGAGTGGTCCGAGCGACATGACGATTCATCGACCGAGGAGACTGCCGCGTTGCTCGATATGCTCAG
ATTGCATCGAGCGAACGTTGCACGATCTGGCGAACAAACGGAGGTTCTTATGACTCAATCCTCGCACGTCAAGGTGATCG
GTCTGCCGCACAGCAAGGATGCTTACGCAATTCGTGACTTTCTGAAGCGTGGTGTGGTTGAGTATGAGTGGTGCGAGTTG
ACTTCCGACAACGACTGCATGCGAGAACTCGGCATCACACCGCTGAGAGACGTTCGGTTACCGGCCGTCATCTTCCCGGA
CGGATCGTGCCTATTTCAACCCACGCTGTCGGAGATTGCGACGAAGCTGGGTTGGGTCGTTCGACCACGCTTCGTCGAAT
ATGACGTCTCTATCTATGGCGCGGGTCCGGCCGGTTTGTCAGCGGCCGTATATGCAGCCTCTGAAGGTCTGAGAGCGGTC
GTGATCGAGCGCAATGCTGTTGGTGGGCAAGCGGGCACGAGTTCTCTTATCGAGAACTATATGGGTTTCCCGGAGGGCAT
CCCCGGAGCGGAGCTCACGGAGCGCGCGCGTCAGCAAGCCGTCAAGTTCGGCGTCGAGCTTTTAATGATGCGTGAGGGCG
TTCATGCATCGTTCGTCGATGGCAAGATCCGCGTCGATCTTGCCGACGGTTCGATCCTGACGGCAAGATCGAACATTTGT
GCGACAGGGATTGAATATCGCAGCCTCAATGTTCCCGATGAGCAGAAGTTTCTCAATGCAGGCCTGTTTTACGGTGCTGG
ATCAAGTGAAGCGCCGATGTGTGAAGGGAAGGAAGTGTTCATCGTCGGCGGCGGAAACTCGGCTGGGCAAGCAGCAATGA
ACTTCTCAAGGCATGCGACCGAAGTCACGTTGATCGTGAGAGGAGCGTCGCTCGCGGCAACACTCTCGCAGTACTTGATC
GAAAGACTGGAGAAAACCGACAACATCAAGGTTCGCTACGGTTCAAAAGTGACGGCGCTCCACGGTGAAGGGACGCTCGA
GGCAATCGAAATCCAATCGGAGCGAGGCGAGAGCGAGGTGGTTCGGACAAGCCACTTGTTCGTTTGTATCGGTGGTGCGC
CGAACACGGAATGGGCGAAGGATACAAGCATCATCCGCAACCCGGATGGCTATTTGGTCACGGGAAGCGATTTGTATGAA
CACCCATCGTTCGAGAAGGTATGGCCGCTGGAACGGCGACCTTATTTTCTGGAGACAAGTGTCCCAGGGTCGTTCGCAGC
GGGCGACGTGCGATCGGGGTCGGTCAAGCGGGTCGCGTCGGCGGTAGGCGAGGGGGCAATGGCCGTGACCTTTGTACACC
GATTTCTTGCGGAAAATTCCCCAGGCCCGGTGAGCACGTGA

Upstream 100 bases:

>100_bases
GATACGGTCGTTCGGGAGATTGTGCAAGAATGAACCGGCAGTGCCATTTTGCACGACCTCTCCGCAGCAGAGTCTGAATA
CTTATTAAACGATCCAAATC

Downstream 100 bases:

>100_bases
GTTCAAACGAATGTGCTGATTCTGCCCGGCAAGCGGTTTTCGGCACGCCCCGGTTCGCAGTGACGTGACATATTAAAAAT
CCTGAAAATTCCTTAATTTT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSCRSEWSERHDDSSTEETAALLDMLRLHRANVARSGEQTEVLMTQSSHVKVIGLPHSKDAYAIRDFLKRGVVEYEWCEL
TSDNDCMRELGITPLRDVRLPAVIFPDGSCLFQPTLSEIATKLGWVVRPRFVEYDVSIYGAGPAGLSAAVYAASEGLRAV
VIERNAVGGQAGTSSLIENYMGFPEGIPGAELTERARQQAVKFGVELLMMREGVHASFVDGKIRVDLADGSILTARSNIC
ATGIEYRSLNVPDEQKFLNAGLFYGAGSSEAPMCEGKEVFIVGGGNSAGQAAMNFSRHATEVTLIVRGASLAATLSQYLI
ERLEKTDNIKVRYGSKVTALHGEGTLEAIEIQSERGESEVVRTSHLFVCIGGAPNTEWAKDTSIIRNPDGYLVTGSDLYE
HPSFEKVWPLERRPYFLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLAENSPGPVST

Sequences:

>Translated_466_residues
MSCRSEWSERHDDSSTEETAALLDMLRLHRANVARSGEQTEVLMTQSSHVKVIGLPHSKDAYAIRDFLKRGVVEYEWCEL
TSDNDCMRELGITPLRDVRLPAVIFPDGSCLFQPTLSEIATKLGWVVRPRFVEYDVSIYGAGPAGLSAAVYAASEGLRAV
VIERNAVGGQAGTSSLIENYMGFPEGIPGAELTERARQQAVKFGVELLMMREGVHASFVDGKIRVDLADGSILTARSNIC
ATGIEYRSLNVPDEQKFLNAGLFYGAGSSEAPMCEGKEVFIVGGGNSAGQAAMNFSRHATEVTLIVRGASLAATLSQYLI
ERLEKTDNIKVRYGSKVTALHGEGTLEAIEIQSERGESEVVRTSHLFVCIGGAPNTEWAKDTSIIRNPDGYLVTGSDLYE
HPSFEKVWPLERRPYFLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLAENSPGPVST
>Mature_465_residues
SCRSEWSERHDDSSTEETAALLDMLRLHRANVARSGEQTEVLMTQSSHVKVIGLPHSKDAYAIRDFLKRGVVEYEWCELT
SDNDCMRELGITPLRDVRLPAVIFPDGSCLFQPTLSEIATKLGWVVRPRFVEYDVSIYGAGPAGLSAAVYAASEGLRAVV
IERNAVGGQAGTSSLIENYMGFPEGIPGAELTERARQQAVKFGVELLMMREGVHASFVDGKIRVDLADGSILTARSNICA
TGIEYRSLNVPDEQKFLNAGLFYGAGSSEAPMCEGKEVFIVGGGNSAGQAAMNFSRHATEVTLIVRGASLAATLSQYLIE
RLEKTDNIKVRYGSKVTALHGEGTLEAIEIQSERGESEVVRTSHLFVCIGGAPNTEWAKDTSIIRNPDGYLVTGSDLYEH
PSFEKVWPLERRPYFLETSVPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLAENSPGPVST

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=339, Percent_Identity=31.2684365781711, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87081763, Length=364, Percent_Identity=30.4945054945055, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320560, Length=338, Percent_Identity=30.1775147928994, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6321898, Length=353, Percent_Identity=29.4617563739377, Blast_Score=128, Evalue=2e-30,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 50522; Mature: 50390

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCRSEWSERHDDSSTEETAALLDMLRLHRANVARSGEQTEVLMTQSSHVKVIGLPHSKD
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCC
AYAIRDFLKRGVVEYEWCELTSDNDCMRELGITPLRDVRLPAVIFPDGSCLFQPTLSEIA
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCEEEECCCCEEECCHHHHHH
TKLGWVVRPRFVEYDVSIYGAGPAGLSAAVYAASEGLRAVVIERNAVGGQAGTSSLIENY
HHHCCEECCEEEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
MGFPEGIPGAELTERARQQAVKFGVELLMMREGVHASFVDGKIRVDLADGSILTARSNIC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCEEEECCCCE
ATGIEYRSLNVPDEQKFLNAGLFYGAGSSEAPMCEGKEVFIVGGGNSAGQAAMNFSRHAT
ECCCEEEECCCCCHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCE
EVTLIVRGASLAATLSQYLIERLEKTDNIKVRYGSKVTALHGEGTLEAIEIQSERGESEV
EEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCCCCE
VRTSHLFVCIGGAPNTEWAKDTSIIRNPDGYLVTGSDLYEHPSFEKVWPLERRPYFLETS
EEEEEEEEEECCCCCCCCCCCCCEEECCCCCEEECCHHHCCCCCCCCCCCCCCCEEEEEC
VPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLAENSPGPVST
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SCRSEWSERHDDSSTEETAALLDMLRLHRANVARSGEQTEVLMTQSSHVKVIGLPHSKD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCC
AYAIRDFLKRGVVEYEWCELTSDNDCMRELGITPLRDVRLPAVIFPDGSCLFQPTLSEIA
HHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCEEEECCCCEEECCHHHHHH
TKLGWVVRPRFVEYDVSIYGAGPAGLSAAVYAASEGLRAVVIERNAVGGQAGTSSLIENY
HHHCCEECCEEEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHH
MGFPEGIPGAELTERARQQAVKFGVELLMMREGVHASFVDGKIRVDLADGSILTARSNIC
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCEEEECCCCE
ATGIEYRSLNVPDEQKFLNAGLFYGAGSSEAPMCEGKEVFIVGGGNSAGQAAMNFSRHAT
ECCCEEEECCCCCHHHHHHCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCE
EVTLIVRGASLAATLSQYLIERLEKTDNIKVRYGSKVTALHGEGTLEAIEIQSERGESEV
EEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCCEEEEEEECCCCCCCE
VRTSHLFVCIGGAPNTEWAKDTSIIRNPDGYLVTGSDLYEHPSFEKVWPLERRPYFLETS
EEEEEEEEEECCCCCCCCCCCCCEEECCCCCEEECCHHHCCCCCCCCCCCCCCCEEEEEC
VPGSFAAGDVRSGSVKRVASAVGEGAMAVTFVHRFLAENSPGPVST
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]