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The map label for this gene is actP [H]

Identifier: 78066429

GI number: 78066429

Start: 1985076

End: 1986710

Strand: Reverse

Name: actP [H]

Synonym: Bcep18194_A4960

Alternate gene names: 78066429

Gene position: 1986710-1985076 (Counterclockwise)

Preceding gene: 78066430

Following gene: 78066428

Centisome position: 53.78

GC content: 59.39

Gene sequence:

>1635_bases
ATGAAGCGTGTACTACTCGCGTCGCTCATCGCGATCGAAGCATTGCCAGCAGTCGCGGCCCAACCTGGATCGCTCACGCA
CGGCCATAATCCGGTCGCAATCGGCATGTTCTTGTTGTTTGTGGCATCGACACTCCTGATCACCCGCTGGGCGGCCCGCA
AAAACCACAGCGTCGCTGATCACTATGCCGCCGGAGGCAAGATTACTGCGTTCCAGAACGGATGGGCGATTGCCGGTGAC
TACATGTCGGCGGCATCTCTGCTCGGCATCTCGGCGCTCGTGTTCACAAGCGGTTACGATGGGCTGATCTATTCCATCGG
ATTTCTCGCGAGCTGGCCCATCATCCTGTTCCTGATCGCCGAGCCGTTGCGCAACCTCGGCAAATACACACTGGCAGACG
TGGTGTCCTACCGGCTCCAGCAACGGCCAATCCGGGCCTTTGCGGCTTCGAGCTCGATCGTCATCGTGCTGCTGTATCTC
GTGTCGCAGATGGTTGGCGCGGGCAAGCTGGTCGAATTGCTGTTCGGCCTGAATTACACCATTGCGGTACTGATCGTCGG
CCTGCTGATGGTCGTCTACGTATTCTTCGGCGGAATGCTGGCAACGACGTGGATTCAGATCGTCAAGGCCGTCCTGCTAC
TCGCCGGCGCAGCATTCATGGCACTCATGGTGCTGAGTCATTTCGGCTTCAGCCTGAACGCCCTTTTCACGCAGGCGGTT
CTCGTGCATTCGAAGCACGATGCCATCATGCGCCCAGGCGGGCTTGTCTCGGATCCGGTTTCCGCTGTATCGCTCGGCCT
CGCGCTGATCTTCGGCACGGCCGGGCTGCCCCATATCCTGATGCGATTCTTCACGGTCGGCAACGTCAAGGCTGCGCGCA
AGAGCATTCTTTACGCCACGGGTATCGTCGGCGTCGGCTACGCATTGATCATCATCATTGGCTTCGGGACAATCGCACTC
GTTGCGTCAAATCCGGAGTATCACAATTCGTCAGGTTCCGTGATCGGCGGCGTGAACATGGTAGCGATCCATCTCGCGCA
CGCGGTGGGGGGAAACGTGTTCCTCGGATTCATCTGCGCAGTCGCATTCTCGACCATTCTTGCAGTGGTAGCCGGCCTGA
CCCTGGCTGGATCGTCCGCGATCTCGCATGACCTGTACGCGAATGTCCTGCGCCGTGGCAATGCGTCTGATCGCGATGAA
ATGCGCGTGGCCCGTATAACCACGCTCGTCCTGGGCGTCCTGGCAGTGCTCCTCGGTATCGCCTTCGAGAAGCAAAACAT
CGCCTTCATTGTCAGTCTTACGTTTTCGATTGCGGCCAGCTCAAACTTCCCGGTCCTACTGCTCTCGATCTATTGGCGCG
GCCTGACCACGCGCGGCGCTGTCATCGGTGGCATGCTCGGTCTCATCACCGCCGTTGTGCTGACCGTATTGAGTCCGACA
GTATGGGTACAGGTTCTTGGCCACGCGCATGCTCTCTACCCGTACGAATACCCCGCACTCTTTTCGATGGCTGTCGCGTT
CGCCGGCATTGTCGTGATTTCCGTTGCGGACAACTCGGCCCGGGCCCGACAGGAGCGCGCACGATTTGACACGCAGCTCG
TCGAGTGCGAATTGGGGGGGACGCGGCACGGTTGA

Upstream 100 bases:

>100_bases
GCATGTTCGCCCTGACATTTGCACTGGTCGCTGTATACGTGTACCGGGCCAATTCCGTCTATGACGCGATCGTCGCGTCG
ATCCGTCAAGGGGACGATCA

Downstream 100 bases:

>100_bases
TTTCCGATCAAATCCCCACACCGCCCGAGCAAAACCAGATCGATAGTGGCATCATTCGATCTCCGATCTGACAACACCGT
GGGACGTTGCAATACGGCAT

Product: Na+/solute symporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MKRVLLASLIAIEALPAVAAQPGSLTHGHNPVAIGMFLLFVASTLLITRWAARKNHSVADHYAAGGKITAFQNGWAIAGD
YMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGKYTLADVVSYRLQQRPIRAFAASSSIVIVLLYL
VSQMVGAGKLVELLFGLNYTIAVLIVGLLMVVYVFFGGMLATTWIQIVKAVLLLAGAAFMALMVLSHFGFSLNALFTQAV
LVHSKHDAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGNVKAARKSILYATGIVGVGYALIIIIGFGTIAL
VASNPEYHNSSGSVIGGVNMVAIHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYANVLRRGNASDRDE
MRVARITTLVLGVLAVLLGIAFEKQNIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVIGGMLGLITAVVLTVLSPT
VWVQVLGHAHALYPYEYPALFSMAVAFAGIVVISVADNSARARQERARFDTQLVECELGGTRHG

Sequences:

>Translated_544_residues
MKRVLLASLIAIEALPAVAAQPGSLTHGHNPVAIGMFLLFVASTLLITRWAARKNHSVADHYAAGGKITAFQNGWAIAGD
YMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGKYTLADVVSYRLQQRPIRAFAASSSIVIVLLYL
VSQMVGAGKLVELLFGLNYTIAVLIVGLLMVVYVFFGGMLATTWIQIVKAVLLLAGAAFMALMVLSHFGFSLNALFTQAV
LVHSKHDAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGNVKAARKSILYATGIVGVGYALIIIIGFGTIAL
VASNPEYHNSSGSVIGGVNMVAIHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYANVLRRGNASDRDE
MRVARITTLVLGVLAVLLGIAFEKQNIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVIGGMLGLITAVVLTVLSPT
VWVQVLGHAHALYPYEYPALFSMAVAFAGIVVISVADNSARARQERARFDTQLVECELGGTRHG
>Mature_544_residues
MKRVLLASLIAIEALPAVAAQPGSLTHGHNPVAIGMFLLFVASTLLITRWAARKNHSVADHYAAGGKITAFQNGWAIAGD
YMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIAEPLRNLGKYTLADVVSYRLQQRPIRAFAASSSIVIVLLYL
VSQMVGAGKLVELLFGLNYTIAVLIVGLLMVVYVFFGGMLATTWIQIVKAVLLLAGAAFMALMVLSHFGFSLNALFTQAV
LVHSKHDAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGNVKAARKSILYATGIVGVGYALIIIIGFGTIAL
VASNPEYHNSSGSVIGGVNMVAIHLAHAVGGNVFLGFICAVAFSTILAVVAGLTLAGSSAISHDLYANVLRRGNASDRDE
MRVARITTLVLGVLAVLLGIAFEKQNIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVIGGMLGLITAVVLTVLSPT
VWVQVLGHAHALYPYEYPALFSMAVAFAGIVVISVADNSARARQERARFDTQLVECELGGTRHG

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=424, Percent_Identity=24.0566037735849, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1790503, Length=547, Percent_Identity=64.8994515539305, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=457, Percent_Identity=27.7899343544858, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 57442; Mature: 57442

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLLASLIAIEALPAVAAQPGSLTHGHNPVAIGMFLLFVASTLLITRWAARKNHSVAD
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HYAAGGKITAFQNGWAIAGDYMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIA
HHCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EPLRNLGKYTLADVVSYRLQQRPIRAFAASSSIVIVLLYLVSQMVGAGKLVELLFGLNYT
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHH
IAVLIVGLLMVVYVFFGGMLATTWIQIVKAVLLLAGAAFMALMVLSHFGFSLNALFTQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LVHSKHDAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGNVKAARKSILYAT
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GIVGVGYALIIIIGFGTIALVASNPEYHNSSGSVIGGVNMVAIHLAHAVGGNVFLGFICA
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHHH
VAFSTILAVVAGLTLAGSSAISHDLYANVLRRGNASDRDEMRVARITTLVLGVLAVLLGI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFEKQNIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVIGGMLGLITAVVLTVLSPT
HCCCCCEEEEEEEEEHHCCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VWVQVLGHAHALYPYEYPALFSMAVAFAGIVVISVADNSARARQERARFDTQLVECELGG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHEEEECCC
TRHG
CCCC
>Mature Secondary Structure
MKRVLLASLIAIEALPAVAAQPGSLTHGHNPVAIGMFLLFVASTLLITRWAARKNHSVAD
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
HYAAGGKITAFQNGWAIAGDYMSAASLLGISALVFTSGYDGLIYSIGFLASWPIILFLIA
HHCCCCEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EPLRNLGKYTLADVVSYRLQQRPIRAFAASSSIVIVLLYLVSQMVGAGKLVELLFGLNYT
HHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHH
IAVLIVGLLMVVYVFFGGMLATTWIQIVKAVLLLAGAAFMALMVLSHFGFSLNALFTQAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LVHSKHDAIMRPGGLVSDPVSAVSLGLALIFGTAGLPHILMRFFTVGNVKAARKSILYAT
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHH
GIVGVGYALIIIIGFGTIALVASNPEYHNSSGSVIGGVNMVAIHLAHAVGGNVFLGFICA
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEECCHHHHHHHHHHHHCCHHHHHHHHH
VAFSTILAVVAGLTLAGSSAISHDLYANVLRRGNASDRDEMRVARITTLVLGVLAVLLGI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AFEKQNIAFIVSLTFSIAASSNFPVLLLSIYWRGLTTRGAVIGGMLGLITAVVLTVLSPT
HCCCCCEEEEEEEEEHHCCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VWVQVLGHAHALYPYEYPALFSMAVAFAGIVVISVADNSARARQERARFDTQLVECELGG
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHEEEECCC
TRHG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA