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The map label for this gene is iorA [H]

Identifier: 78066426

GI number: 78066426

Start: 1981682

End: 1982182

Strand: Reverse

Name: iorA [H]

Synonym: Bcep18194_A4957

Alternate gene names: 78066426

Gene position: 1982182-1981682 (Counterclockwise)

Preceding gene: 78066427

Following gene: 78066425

Centisome position: 53.66

GC content: 60.48

Gene sequence:

>501_bases
ATGATCGCCATCACCGTGAACAGTGTCCAGCACACACTCGACATCGATCCCACGACTCCACTCCTGTATGTGCTGCGCAA
CGACCTGCATCTGCACGGAGCAAAGTTCGGGTGTGGTCTCGGACAATGTGGCGCATGTACCGTGATTGTCGACGACAAGC
CGATGTTTTCCTGCCTGATTCCGATCGCCGCCATCGGGCAACGCCACGTCAGGACCATTGAAAGTCTCGGCACGTTGGAG
CGGCCTGGGCCGCTCCAACGTGCCTTCATCGATCATCAGGCCGCACAATGCGGCTATTGCATCGCCGGAATGATCATGCG
TGCGCAGGCGTTGCTCGAACGGAACCCCCACCCGACGGAAAGCGAGTTGCGCGCACACATGGAGCCGAACCTGTGCCGTT
GCGGAACCCACATGCGTATCCTGGCGGCCGTGCGTCAGGTCGCGGGCTTACAGCAACCGGAAAACGCTTCCGAACCCGTG
ACGGTCAGCAAGGCCCTCTGA

Upstream 100 bases:

>100_bases
CGGATCTGGTGGCTTACATCCGTGGTGCGTATTCGGATCGCCCCGCATGGACCGGGATCGAAGCCATGGCCGCGAAACTC
AGGAAGGAGGACGGAGCGCG

Downstream 100 bases:

>100_bases
TGAACGACCTCGAGAACCAACACGACGACATAGACGAAGGTCGCCGGAATTTCATCGTCTCAAGTGCGCTCTTCGTCGCA
TTCAGCCTTGCTCCGGCCTC

Product: ferredoxin/(2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MIAITVNSVQHTLDIDPTTPLLYVLRNDLHLHGAKFGCGLGQCGACTVIVDDKPMFSCLIPIAAIGQRHVRTIESLGTLE
RPGPLQRAFIDHQAAQCGYCIAGMIMRAQALLERNPHPTESELRAHMEPNLCRCGTHMRILAAVRQVAGLQQPENASEPV
TVSKAL

Sequences:

>Translated_166_residues
MIAITVNSVQHTLDIDPTTPLLYVLRNDLHLHGAKFGCGLGQCGACTVIVDDKPMFSCLIPIAAIGQRHVRTIESLGTLE
RPGPLQRAFIDHQAAQCGYCIAGMIMRAQALLERNPHPTESELRAHMEPNLCRCGTHMRILAAVRQVAGLQQPENASEPV
TVSKAL
>Mature_166_residues
MIAITVNSVQHTLDIDPTTPLLYVLRNDLHLHGAKFGCGLGQCGACTVIVDDKPMFSCLIPIAAIGQRHVRTIESLGTLE
RPGPLQRAFIDHQAAQCGYCIAGMIMRAQALLERNPHPTESELRAHMEPNLCRCGTHMRILAAVRQVAGLQQPENASEPV
TVSKAL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=144, Percent_Identity=37.5, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=38.6503067484663, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=36.551724137931, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17539860, Length=141, Percent_Identity=39.0070921985816, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=141, Percent_Identity=36.8794326241135, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=145, Percent_Identity=36.551724137931, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737937, Length=141, Percent_Identity=35.4609929078014, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647199, Length=142, Percent_Identity=31.6901408450704, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647197, Length=180, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647195, Length=180, Percent_Identity=28.8888888888889, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647201, Length=155, Percent_Identity=29.6774193548387, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18054; Mature: 18054

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAITVNSVQHTLDIDPTTPLLYVLRNDLHLHGAKFGCGLGQCGACTVIVDDKPMFSCLI
CEEEEEECCEEEEECCCCCHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCCCHHHHHH
PIAAIGQRHVRTIESLGTLERPGPLQRAFIDHQAAQCGYCIAGMIMRAQALLERNPHPTE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SELRAHMEPNLCRCGTHMRILAAVRQVAGLQQPENASEPVTVSKAL
HHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCC
>Mature Secondary Structure
MIAITVNSVQHTLDIDPTTPLLYVLRNDLHLHGAKFGCGLGQCGACTVIVDDKPMFSCLI
CEEEEEECCEEEEECCCCCHHHHHHHCCCEECCCCCCCCCCCCCEEEEEECCCCHHHHHH
PIAAIGQRHVRTIESLGTLERPGPLQRAFIDHQAAQCGYCIAGMIMRAQALLERNPHPTE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
SELRAHMEPNLCRCGTHMRILAAVRQVAGLQQPENASEPVTVSKAL
HHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]